Bhojwani D, Yang JJ, Pui CH. Biology of Childhood Acute lymphoblastic leukemia. Pediatr Clin North Am. 2015;62(1):47–60. https://doi.org/10.1016/j.pcl.2014.09.004.

Article  PubMed  PubMed Central  Google Scholar 

Madhusoodhan PP, Carroll WL, Bhatla T. Progress and prospects in pediatric leukemia. Curr Probl Pediatr Adolesc Health Care. 2016;46(7):229–41. https://doi.org/10.1016/j.cppeds.2016.04.003.

Article  PubMed  Google Scholar 

Du M, Chen W, Liu K, Wang L, Hu Y, Mao Y, et al. The Global Burden of Leukemia and Its Attributable Factors in 204 Countries and Territories: Findings from the Global Burden of Disease 2019 Study and Projections to 2030. J Oncol. 2022;2022:1–14. https://doi.org/10.1155/2022/1612702.

Article  Google Scholar 

Blackburn LM, Bender S, Brown S. Acute leukemia: diagnosis and treatment. Semin Oncol Nurs. 2019;35(6):150950. https://doi.org/10.1016/j.soncn.2019.150950.

Article  PubMed  Google Scholar 

Saghir SAM. A new insight updates in diagnosis and management of acute lymphoblastic leukemia, cytogenetics, immunophenotyping, and proteomic profile. Electronic Journal of General Medicine 2023;20(5):em519. https://doi.org/10.29333/ejgm/13386

Terwilliger T, Abdul-Hay M. Acute lymphoblastic leukemia: a comprehensive review and 2017 update. Blood Cancer J. 2017;7(6):e577. https://doi.org/10.1038/bcj.2017.53.doi:10.1038/bcj.2017.53.

Malczewska M, Kośmider K, Bednarz K, Ostapińska K, Lejman M, Zawitkowska J. Recent advances in treatment options for childhood acute lymphoblastic leukemia. Cancers. 2022;14(8):2021. https://doi.org/10.3390/cancers14082021.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mengxuan S, Fen Z, Runming J. Novel treatments for pediatric relapsed or refractory acute B-Cell lineage lymphoblastic leukemia: Precision Medicine ERA. Frontiers in Pediatrics 2022;10, https://doi.org/10.3389/fped.2022.923419.

Whitehead TP, Metayer C, Wiemels JL, Singer AW, Miller MD. Childhood leukemia and primary prevention. Curr Probl Pediatr Adolesc Health Care. 2016;46(10):317–52. https://doi.org/10.1016/j.cppeds.2016.08.004.

Article  PubMed  PubMed Central  Google Scholar 

Porter CC, Druley TE, Erez A, Kuiper RP, Onel K, Schiffman JD, et al. Recommendations for Surveillance for Children with Leukemia-Predisposing Conditions. Clin Cancer Res. 2017;23(11):e14–22. https://doi.org/10.1158/1078-0432.ccr-17-0428.

Article  PubMed  Google Scholar 

Al-Mahayri ZN, AlAhmad MM, Ali BR. Long-Term effects of Pediatric Acute lymphoblastic leukemia chemotherapy: Can recent findings inform old strategies? Frontiers in Oncology 2021;11. https://doi.org/10.3389/fonc.2021.710163.

Brayley J, Stanton LK, Jenner L, Paul SP. Recognition and management of leukaemia in children. British J Nurs 2019;28(15):985–992. https://doi.org/10.12968/bjon.2019.28.15.985.

Clarke RT, Van Den Bruel A, Bankhead C, Mitchell CD, Phillips B, Thompson MJ. Clinical presentation of childhood leukaemia: a systematic review and meta-analysis. Arch Dis Child. 2016;101(10):894–901. https://doi.org/10.1136/archdischild-2016-311251.

Article  PubMed  Google Scholar 

Davis AS, Viera AJ, Mead MD. Leukemia: an overview for primary care. Am Fam Physician. 2014;89(9):731–8.

PubMed  Google Scholar 

Jaime-Pérez JC, García-Arellano G, Herrera-Garza JL, Marfil-Rivera LJ, Gómez-Almaguer D. Revisiting the complete blood count and clinical findings at diagnosis of childhood acute lymphoblastic leukemia: 10-year experience at a single center. Hematology Transfusion and Cell Therapy. 2019;41(1):57–61. https://doi.org/10.1016/j.htct.2018.05.010.

Article  PubMed  Google Scholar 

Sekar MD, Raj M, Manivannan P. Role of Morphology in the diagnosis of Acute leukemias: Systematic review. Indian Journal of Medical and Paediatric Oncology. 2023;44(5):464–73. https://doi.org/10.1055/s-0043-1764369.

Article  Google Scholar 

Bhaskar N. Bone marrow Aspiration and Biopsy in critical Pediatric Patients: A Pathologist’s perspective. Cureus. 2021;13(8):e17423. https://doi.org/10.7759/cureus.17423.

Article  PubMed  PubMed Central  Google Scholar 

Wang X, Lebrec H. Immunophenotyping: application to safety assessment. Toxicol Pathol. 2017;45(7):1004–11. https://doi.org/10.1177/0192623317736742.

Article  PubMed  Google Scholar 

Chiaretti S, Zini G, Bassan R. Diagnosis and Subclassification of Acute lymphoblastic Leukemia. Mediterranean J Hematol Infect Dis. 2014;6(1):e2014073. https://doi.org/10.4084/mjhid.2014.073.

Article  Google Scholar 

Ozkan E, Lacerda MP. Genetics, cytogenetic testing and conventional karyotype. 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan

Ashok V, Ranganathan R, Chander S, Damodar S, Bhat S, S NK, et al. Comparison of diagnostic yield of a FISH panel against conventional cytogenetic studies for hematological malignancies: a South Indian referral laboratory analysis of 201 cases. Asian Pac J Cancer Prev. 2017 Dec 29;18(12):3457–3464. https://doi.org/10.22034/APJCP.2017.18.12.3457.

Limsuwanachot N, Siriboonpiputtana T, Karntisawiwat K, Chareonsirisuthigul T, Chuncharunee S, Rerkamnuaychoke B. Multiplex RT-PCR assay for detection of common fusion transcripts in acute lymphoblastic leukemia and chronic myeloid leukemia cases. Asian Pac J Cancer Prev. 2016;17(2):677–84. https://doi.org/10.7314/apjcp.2016.17.2.677.

Article  PubMed  Google Scholar 

Kim B, Kim E, Lee ST, Cheong JW, Lyu CJ, Min YH, et al. Detection of recurrent, rare, and novel gene fusions in patients with acute leukemia using next-generation sequencing approaches. Hematol Oncol. 2020;38(1):82–8. https://doi.org/10.1002/hon.2709.

Article  CAS  PubMed  Google Scholar 

Qin D. Next-generation sequencing and its clinical application. Cancer Biology and Medicine 2019;16(1):4–10. https://doi.org/10.20892/j.issn.2095-3941.2018.0055.

Elsayed B, Elhadary M, Elshoeibi RM, Elshoeibi AM, Badr A, et al. Deep learning enhances acute lymphoblastic leukemia diagnosis and classification using bone marrow images. Front Oncol. 2023;13:1330977. https://doi.org/10.3389/fonc.2023.1330977.

Article  PubMed  PubMed Central  Google Scholar 

Wu Y, Deng Y, Wei B, Xiang D, Hu J, et al. Global, regional, and national childhood cancer burden, 1990–2019: An analysis based on the Global Burden of Disease Study 2019. J Adv Res. 2022;2022(40):233–47. https://doi.org/10.1016/j.jare.2022.06.001.

Article  Google Scholar 

Namayandeh SM, Khazaei Z,. Najafi ML, Goodarzi E, Moslem A. GLOBAL Leukemia in Children 0–14 Statistics 2018, Incidence and Mortality and Human Development Index (HDI): GLOBOCAN Sources and methods. Asian Pacific J Cancer Prevent 2020;21(5):1487–1494. https://doi.org/10.31557/apjcp.2020.21.5.1487.

Devilli L, Garonzi C, Balter R, Bonetti E, Chinello M, Zaccaron A, et al. Long-Term and Quality of Survival in Patients Treated for Acute Lymphoblastic Leukemia during the Pediatric Age. Hematol Rep. 2021;13(2):8847. https://doi.org/10.4081/hr.2021.8847.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Inaba H, Mullighan CG. Pediatric acute lymphoblastic leukemia. Haematologica. 2020;105(11):2524–39. https://doi.org/10.3324/haematol.2020.247031.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mejía-Aranguré JM. Etiology of acute leukemias in children. Springer. 2016. https://doi.org/10.1007/978-3-319-05798-9.

Article  Google Scholar 

Qian J, Li Z, Pei K, Li Z, Li C, Yan M, et al. Effects of NRAS mutations on leukemogenesis and targeting of children with acute lymphoblastic leukemia. Frontiers Cell Develop Biol. 2022;10:712484. https://doi.org/10.3389/fcell.2022.712484.

Article  Google Scholar 

Huang F, Liao E, Li C, Yen C, Yu S. Pathogenesis of pediatric B-cell acute lymphoblastic leukemia: Molecular pathways and disease treatments (Review). Oncol Lett. 2020;20(1):448–54. https://doi.org/10.3892/ol.2020.11583.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kaczmarska A, Derebas J, Pinkosz M, Niedźwiecki M, Lejman M. The Landscape of Secondary Genetic Rearrangements in Pediatric Patients with B-Cell Acute Lymphoblastic Leukemia with t(12;21). Cells. 2023;12(3):357. https://doi.org/10.3390/cells12030357.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Iacobucci I, Mullighan CG. Genetic basis of acute lymphoblastic leukemia. J Clin Oncol. 2017;35(9):975–83. https://doi.org/10.1200/jco.2016.70.7836.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marke R, Van Leeuwen FN, Scheijen B. The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia. Haematologica. 2018;103(4):565–74. https://doi.org/10.3324/haematol.2017.185603.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fattizzo B, Rosa J, Giannotta JA, Baldini L, Fracchiolla NS. The Physiopathology of T- cell acute lymphoblastic leukemia: Focus on molecular aspects. Front Oncol. 2020;10:273. https://doi.org/10.3389/fonc.2020.00273.

Article  PubMed  PubMed Central  Google Scholar 

Ong JZL, Tan TK, Wang L, Tan SH, Sanda T. Regulatory mechanisms and context-dependent roles of TAL1 in T-cell acute lymphoblastic leukemia. Haematologica. 2023;109(5):1359–72. https://doi.org/10.3324/haematol.2023.283450.