The inhibitory effect of salidroside on RANKL-induced osteoclast formation via NFκB suppression

Alperth F, Turek I, Weiss S, Vogt D, Bucar F (2019) Qualitative and quantitative analysis of different Rhodiola rosea rhizome extracts by UHPLC-DAD-ESI-MSn. Sci Pharm 87:8

Article  CAS  Google Scholar 

Bai L, Fu M (2022) Traditional Mongolian medicine: past, present and future. Chin Herb Med 14:343–344

PubMed  PubMed Central  Google Scholar 

Baldandorj D PA, Kharlampovich SS (1990) Использование магнитного поля и золотого корня алтангагнуур при лечении переломов костей. Госиздат; Улаанбаатар

Batoon L, Millard SM, Raggatt LJ, Pettit AR (2017) Osteomacs and bone regeneration. Curr Osteoporos Rep 15:385–395

Article  PubMed  Google Scholar 

Bold S (2011) History of Traditional Mongolian Medicine. Admon Printing , pp 7–12

Bozec A, Soulat D (2017) Latest perspectives on macrophages in bone homeostasis. Pflugers Arch 469:517–525

Article  CAS  PubMed  Google Scholar 

Chen D, Lu D, Liu H, Xue E, Zhang Y, Shang P, Pan X (2019) Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-α-driven inflammation and ER stress. EBioMedicine 50:395–407

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Q, Yang L, Zhang G, Wang F (2013) Bioactivity-guided isolation of antiosteoporotic compounds from Ligustrum lucidum. Phytother Res 27:973–979

Article  CAS  PubMed  Google Scholar 

Chen XF, Li XL, Yang M, Song Y, Zhang Y (2018) Osteoprotective effects of salidroside in ovariectomized mice and diabetic mice. Eur J Pharmacol 819:281–288

Article  CAS  PubMed  Google Scholar 

Drake MT, Cremers S, Russell RG, Bilezikian JP (2019) Drugs for the treatment of metabolic bone diseases. Br J Clin Pharmacol 85:1049–1051

Article  PubMed  PubMed Central  Google Scholar 

Florencio-Silva R, Sasso GR, Sasso-Cerri E, Simões MJ, Cerri PS (2015) Biology of bone tissue: structure, function, and factors that influence bone cells. Biomed Res Int 2015:421746

Article  PubMed  PubMed Central  Google Scholar 

Fu S, Yan M, Fan Q, Xu J (2022) Salidroside promotes osteoblast proliferation and differentiation via the activation of AMPK to inhibit bone resorption of knee osteoarthritis mice. Tissue Cell 79:101917

Article  CAS  PubMed  Google Scholar 

Guan S, Feng H, Song B, Guo W, Xiong Y, Huang G, Zhong W, Huo M, Chen N, Lu J, Deng X (2011) Salidroside attenuates LPS-induced pro-inflammatory cytokine responses and improves survival in murine endotoxemia. Int Immunopharmacol 11:2194–2199

Article  CAS  PubMed  Google Scholar 

Guan S, Xiong Y, Song B, Song Y, Wang D, Chu X, Chen N, Huo M, Deng X, Lu J (2012) Protective effects of salidroside from Rhodiola rosea on LPS-induced acute lung injury in mice. Immunopharmacol Immunotoxicol 34:667–672

Article  CAS  PubMed  Google Scholar 

He J, Li X, Wang Z, Bennett S, Chen K, Xiao Z, Zhan J, Chen S, Hou Y, Chen J, Wang S, Xu J, Lin D (2019) Therapeutic anabolic and anticatabolic benefits of natural Chinese medicines for the treatment of osteoporosis. Front Pharmacol 10:1344

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ikeda F, Nishimura R, Matsubara T, Tanaka S, Inoue J, Reddy SV, Hata K, Yamashita K, Hiraga T, Watanabe T, Kukita T, Yoshioka K, Rao A, Yoneda T (2004) Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J Clin Invest 114:475–484

Article  CAS  PubMed  PubMed Central  Google Scholar 

Koide N, Kondo Y, Odkhuu E, Ulziisaikhan J, Ukaji T, Yokochi T, Umezawa K (2014) Inhibition of receptor activator of nuclear factor-κB ligand- or lipopolysaccharide-induced osteoclast formation by conophylline through downregulation of CREB. Immunol Lett 161:31–37

Article  CAS  PubMed  Google Scholar 

Kong L, Smith W, Hao D (2019) Overview of RAW 264.7 for osteoclastogensis study: phenotype and stimuli. J Cell Mol Med 23:3077–3087

Article  PubMed  PubMed Central  Google Scholar 

Liu X, Wen S, Yan F, Liu K, Liu L, Wang L, Zhao S, Ji X (2018) Salidroside provides neuroprotection by modulating microglial polarization after cerebral ischemia. J Neuroinflammation 15:39

Article  PubMed  PubMed Central  Google Scholar 

Liu Y, Wang J, Wang L, Zhang C, Bai Q, Lyu X, Yang R (2022) Biosynthesis and biotechnological production of salidroside from Rhodiola genus plants. Phytochem Rev 21:1605–1626

Article  CAS  Google Scholar 

Loukas AT, Papadourakis M, Panagiotopoulos V, Zarmpala A, Chontzopoulou E, Christodoulou S, Katsila T, Zoumpoulakis P, Matsoukas MT (2024) Natural compounds for bone remodeling: a computational and experimental approach targeting bone metabolism-related proteins. Int J Mol Sci 25:5047

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matsuo K, Galson DL, Zhao C, Peng L, Laplace C, Wang KZ, Bachler MA, Amano H, Aburatani H, Ishikawa H, Wagner EF (2004) Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos. J Biol Chem 279:26475–26480

Article  CAS  PubMed  Google Scholar 

Mendjargal A, Odkhuu E, Koide N, Nagata H, Kurokawa T, Nonami T, Yokochi T (2013) Pifithrin-α, a pharmacological inhibitor of p53, downregulates lipopolysaccharide-induced nitric oxide production via impairment of the MyD88-independent pathway. Int Immunopharmacol 15:671–678

Article  CAS  PubMed  Google Scholar 

Natesan V, Kim SJ (2022) Metabolic bone diseases and new drug developments. Biomol Ther (Seoul) 30:309–319

Article  CAS  PubMed  Google Scholar 

Odkhuu E, Koide N, Haque A, Tsolmongyn B, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T (2012) Inhibition of receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation by pyrroloquinoline quinine (PQQ). Immunol Lett 142:34–40

Article  CAS  PubMed  Google Scholar 

Odkhuu E, Koide N, Tsolmongyn B, Jambalganiin U, Naiki Y, Komatsu T, Yoshida T, Yokochi T (2015) Involvement of redox balance in in vitro osteoclast formation of RAW 264.7 macrophage cells in response to LPS. Innate Immun 21:194–202

Article  PubMed  Google Scholar 

Odkhuu E, Narmandakh S, Zinamyadar M, Bold J, Amgalanbaatar A, Sundui E (2020) Vitamin regulation of osteoclast differentiation. CAJMS 6:114–128

Article  Google Scholar 

Oh JH, Karadeniz F, Lee JI, Seo Y, Kong CS (2021) Ligustrum japonicum Thunb. fruits exert antiosteoporotic properties in bone marrow-derived mesenchymal stromal cells via regulation of adipocyte and osteoblast differentiation. Stem Cells Int 2021:8851884

Article  PubMed  PubMed Central  Google Scholar 

Siu WS, Shiu HT, Shum WT, Ko Chun H, Lau CBS, Hung Leung K, Leung Ping C (2019) Chinese topical herbal medicine gives additive effect on pharmaceutical agent on fracture healing. J Tradit Chin Med 39:853–860

PubMed  Google Scholar 

Tao H, Wu X, Cao J, Peng Y, Wang A, Pei J, Xiao J, Wang S, Wang Y (2019) Rhodiola species: a comprehensive review of traditional use, phytochemistry, pharmacology, toxicity, and clinical study. Med Res Rev 39:1779–1850

Article  CAS  PubMed  Google Scholar 

Wang HW, Wu T, Qi JY, Wang YQ, Luo XP, Ning Q (2013) Salidroside attenuates LPS-stimulated activation of THP-1 cell-derived macrophages through down-regulation of MAPK/NF-kB signaling pathways. J Huazhong Univ Sci Technolog Med Sci 33:463–469

Article  CAS  PubMed  Google Scholar 

Wang XL, Sun RX, Li DX, Chen ZG, Li XF, Sun SY, Lin F, Zhao GA (2023) Salidroside regulates mitochondrial homeostasis after polarization of RAW264.7 macrophages. J Cardiovasc Pharmacol 81:85–92

Article  CAS  PubMed  Google Scholar 

Wang YF, Chang YY, Zhang XM, Gao MT, Zhang QL, Li X, Zhang L, Yao WF (2022) Salidroside protects against osteoporosis in ovariectomized rats by inhibiting oxidative stress and promoting osteogenesis via Nrf2 activation. Phytomedicine 99:154020

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