A Retrospective Tribute to Dr. Harish Pant (1938–2023) and His Seminal Work on Cyclin Dependent Kinase 5

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Rudrabhatla P, Grant P, Jaffe H, Strong MJ, Pant HC (2010) Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer’s disease by iTRAQ. FASEB J 24:4396–4407. https://doi.org/10.1096/fj.10-157859Epub 2010 Jul 12

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Sharma P, Barchi JJ Jr, Huang X, Amin ND, Jaffe H, Pant HC (1998) Site-specific phosphorylation of Lys-Ser-Pro repeat peptides from neurofilament H by cyclin-dependent kinase 5: structural basis for substrate recognition. Biochemistry 37:4759–4766. https://doi.org/10.1021/bi972746o

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Veeranna, Amin ND, Ahn NG, Jaffe H, Winters CA, Grant P, Pant HC (1998) Mitogen-activated protein kinases (Erk1,2) phosphorylate lys-ser-pro (KSP) repeats in neurofilament proteins NF-H and NF-M. J Neurosci 18:4008–4021. https://doi.org/10.1523/JNEUROSCI.18-11-04008.1998

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Pareek TK, Keller J, Kesavapany S, Pant HC, Iadarola MJ, Brady RO, Kulkarni AB (2006) Cyclin-dependent kinase 5 activity regulates pain signaling. Proc Natl Acad Sci U S A 103:791–796. https://doi.org/10.1073/pnas.0510405103Epub 2006 Jan 9

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Tiwari MN, Hall BE, Ton AT, Ghetti R, Terse A, Amin N, Chung MK, Kulkarni AB (2023) Activation of cyclin-dependent kinase 5 broadens action potentials in human sensory neurons. Mol Pain 19:17448069231218353. https://doi.org/10.1177/17448069231218353

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Saito T, Yano M, Kawai Y, Asada A, Wada M, Doi H, Hisanaga SI (2013) Structural basis for the different stability and activity between the Cdk5 complexes with p35 and p39 activators. J Biol Chem 288:32433–32439. https://doi.org/10.1074/jbc.M113.512293Epub 2013 Sep 30

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Amin ND, Albers W, Pant HC (2002) Cyclin-dependent kinase 5 (cdk5) activation requires interaction with three domains of p35. J Neurosci Res 67:354–362. https://doi.org/10.1002/jnr.10116

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