Lederberg, J. & Tatum, E. L. Gene recombination in Escherichia coli. Nature 158, 558 (1946).
Article CAS PubMed Google Scholar
Zinder, N. D. & Lederberg, J. Genetic exchange in Salmonella. J. Bacteriol. 64, 679–699 (1952).
Article CAS PubMed PubMed Central Google Scholar
Hill, M. J. in Human Microbial Ecology (eds Hill, M. J. & Marsh, P. D.) 57–85 (CRC Press, 2020).
Zoetendal, E. G. et al. The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates. ISME J. 6, 1415–1426 (2012).
Article CAS PubMed PubMed Central Google Scholar
Shalon, D. et al. Profiling the human intestinal environment under physiological conditions. Nature 617, 581–591 (2023).
Article CAS PubMed PubMed Central Google Scholar
Javan, G. T. et al. Correlation between postmortem microbial signatures and substance abuse disorders. PLoS ONE 17, e0274401 (2022).
Article CAS PubMed PubMed Central Google Scholar
Pechal, J. L., Schmidt, C. J., Jordan, H. R. & Benbow, M. E. A large-scale survey of the postmortem human microbiome, and its potential to provide insight into the living health condition. Sci. Rep. 8, 5724 (2018).
Article PubMed PubMed Central Google Scholar
DeBruyn, J. M. & Hauther, K. A. Postmortem succession of gut microbial communities in deceased human subjects. PeerJ 5, e3437 (2017).
Article PubMed PubMed Central Google Scholar
Debongnie, J. C. & Phillips, S. F. Capacity of the human colon to absorb fluid. Gastroenterology 74, 698–703 (1978).
Article CAS PubMed Google Scholar
Uchimura, Y. et al. Antibodies set boundaries limiting microbial metabolite penetration and the resultant mammalian host response. Immunity 49, 545–559.e5 (2018).
Article CAS PubMed PubMed Central Google Scholar
Kverka, M. & Tlaskalova-Hogenova, H. Intestinal microbiota: facts and fiction. Dig. Dis. 35, 139–147 (2017).
Albenberg, L. et al. Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota. Gastroenterology 147, 1055–1063.e8 (2014).
Shafik, A., El-Sibai, O. & Shafik, A. A. Physiological assessment of the function of the ileocecal junction with evidence of ileocecal junction reflexes. Med. Sci. Monit. 8, CR629–CR635 (2002).
Dinning, J. P. & Hixson, L. J. Value of flexible sigmoldoscopy – reply. Arch. Intern. Med. 155, 427–427 (1995).
Malbert, C. H. The ileocolonic sphincter. Neurogastroenterol. Motil. 17, 41–49 (2005).
Hugenholtz, F. & de Vos, W. M. Mouse models for human intestinal microbiota research: a critical evaluation. Cell. Mol. Life Sci. 75, 149–160 (2018).
Article CAS PubMed Google Scholar
Casteleyn, C., Rekecki, A., Van der Aa, A., Simoens, P. & Van den Broeck, W. Surface area assessment of the murine intestinal tract as a prerequisite for oral dose translation from mouse to man. Lab. Anim. 44, 176–183 (2010).
Article CAS PubMed Google Scholar
Evans, D. F. et al. Measurement of gastrointestinal pH profiles in normal ambulant human subjects. Gut 29, 1035–1041 (1988).
Article CAS PubMed PubMed Central Google Scholar
Lkhagva, E. et al. The regional diversity of gut microbiome along the GI tract of male C57BL/6 mice. BMC Microbiol. 21, 44 (2021).
Article CAS PubMed PubMed Central Google Scholar
Maurer, J. M. et al. Gastrointestinal pH and transit time profiling in healthy volunteers using the IntelliCap system confirms ileo-colonic release of colopulse tablets. PLoS ONE 10, e0129076 (2015).
Article PubMed PubMed Central Google Scholar
Frey, J. C. et al. Comparative studies of microbial populations in the rumen, duodenum, ileum and faeces of lactating dairy cows. J. Appl. Microbiol. 108, 1982–1993 (2010).
Zheng, L., Kelly, C. J. & Colgan, S. P. Physiologic hypoxia and oxygen homeostasis in the healthy intestine. a review in the theme: cellular responses to hypoxia. Am. J. Physiol. Cell Physiol. 309, C350–C360 (2015).
Article CAS PubMed PubMed Central Google Scholar
Nijnik, A. & Hancock, R. Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections. Emerg. Health Threat. J. 2, e1 (2009).
Kiela, P. R. & Ghishan, F. K. Physiology of intestinal absorption and secretion. Best. Pract. Res. Clin. Gastroenterol. 30, 145–159 (2016).
Article CAS PubMed PubMed Central Google Scholar
Volk, N. & Lacy, B. Anatomy and physiology of the small bowel. Gastrointest. Endosc. Clin. N. Am. 27, 1–13 (2017).
Szarka, L. A. & Camilleri, M. Methods for the assessment of small-bowel and colonic transit. Semin. Nucl. Med. 42, 113–123 (2012).
Article PubMed PubMed Central Google Scholar
Li, N. et al. Microbiome-encoded bile acid metabolism modulates colonic transit times. iScience 24, 102508 (2021).
Article CAS PubMed PubMed Central Google Scholar
Cummings, D. E. & Overduin, J. Gastrointestinal regulation of food intake. J. Clin. Invest. 117, 13–23 (2007).
Article CAS PubMed PubMed Central Google Scholar
Martinez-Guryn, K., Leone, V. & Chang, E. B. Regional diversity of the gastrointestinal microbiome. Cell Host Microbe 26, 314–324 (2019).
Article CAS PubMed PubMed Central Google Scholar
Begley, M., Gahan, C. G. & Hill, C. The interaction between bacteria and bile. FEMS Microbiol. Rev. 29, 625–651 (2005).
Article CAS PubMed Google Scholar
Thanassi, D. G., Cheng, L. W. & Nikaido, H. Active efflux of bile salts by Escherichia coli. J. Bacteriol. 179, 2512–2518 (1997).
Article CAS PubMed PubMed Central Google Scholar
Buffie, C. G. & Pamer, E. G. Microbiota-mediated colonization resistance against intestinal pathogens. Nat. Rev. Immunol. 13, 790–801 (2013).
Article CAS PubMed PubMed Central Google Scholar
Miller, W. R., Munita, J. M. & Arias, C. A. Mechanisms of antibiotic resistance in enterococci. Expert. Rev. Anti Infect. Ther. 12, 1221–1236 (2014).
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