Pedretti RFE, Hansen D, Ambrosetti M, Back M, Berger T, Ferreira MC, et al. How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases: a clinical consensus statement from the European Association of Preventive Cardiology. Eur J Prev Cardiol. 2023;30(2):149–66. https://doi.org/10.1093/eurjpc/zwac204.
Farhat G, Drummond S, Al-Dujaili EAS. Polyphenols and their role in obesity management: a systematic review of randomized clinical trials. Phytother Res. 2017;31(7):1005–18. https://doi.org/10.1002/ptr.5830.
Article CAS PubMed Google Scholar
Catalkaya G, Venema K, Lucini L, Rocchetti G, Delmas D, Daglia M, et al. Interaction of dietary polyphenols and gut microbiota: microbial metabolism of polyphenols, influence on the gut microbiota, and implications on host health. Food Front. 2020;1(2):109–33. https://doi.org/10.1002/fft2.25.
Chen L, Cao H, Xiao J. 2 - polyphenols: absorption, bioavailability, and metabolomics. In: Galanakis CM, editor. Polyphenols: properties, recovery, and applications. Sawston: Woodhead Publishing; 2018. p. 45–67.
Andres-Lacueva C, Macarulla MT, Rotches-Ribalta M, Boto-Ordóñez M, Urpi-Sarda M, Rodríguez VM, et al. Distribution of resveratrol metabolites in liver, adipose tissue, and skeletal muscle in rats fed different doses of this polyphenol. J Agric Food Chem. 2012;60(19):4833–40. https://doi.org/10.1021/jf3001108.
Article CAS PubMed Google Scholar
Janle EM, Lila MA, Grannan M, Wood L, Higgins A, Yousef GG, et al. Pharmacokinetics and tissue distribution of 14C-labeled grape polyphenols in the periphery and the central nervous system following oral administration. J Med Food. 2010;13(4):926–33. https://doi.org/10.1089/jmf.2009.0157.
Article CAS PubMed PubMed Central Google Scholar
Les F, Carpéné C, Arbonés-Mainar JM, Decaunes P, Valero MS, López V. Pomegranate juice and its main polyphenols exhibit direct effects on amine oxidases from human adipose tissue and inhibit lipid metabolism in adipocytes. J Funct Foods. 2017;33:323–31.
Assini JM, Mulvihill EE, Burke AC, Sutherland BG, Telford DE, Chhoker SS, et al. Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21. Endocrinology. 2015;156(6):2087–102. https://doi.org/10.1210/en.2014-2003.
Article CAS PubMed Google Scholar
Chtourou Y, Fetoui H, Jemai R, ben Slima A, Makni M, Gdoura R. Naringenin reduces cholesterol-induced hepatic inflammation in rats by modulating matrix metalloproteinases-2, 9 via inhibition of nuclear factor κB pathway. Eur J Pharmacol. 2015;746:96–105.
Article CAS PubMed Google Scholar
Mayneris-Perxachs J, Alcaide-Hidalgo JM, de la Hera E, del Bas JM, Arola L, Caimari A. Supplementation with biscuits enriched with hesperidin and naringenin is associated with an improvement of the Metabolic Syndrome induced by a cafeteria diet in rats. J Funct Foods. 2019;61:103504.
Demonty I, Lin Y, Zebregs YEMP, Vermeer MA, van der Knaap HCM, Jäkel M, et al. The citrus flavonoids hesperidin and naringin do not affect serum cholesterol in moderately hypercholesterolemic men and women. J Nutr. 2010;140(9):1615–20. https://doi.org/10.3945/jn.110.124735.
Article CAS PubMed Google Scholar
Bolca S, van de Wiele T, Possemiers S. Gut metabotypes govern health effects of dietary polyphenols. Curr Opin Biotechnol. 2013;24(2):220–5.
Article CAS PubMed Google Scholar
Mena P, Ludwig IA, Tomatis VB, Acharjee A, Calani L, Rosi A, et al. Inter-individual variability in the production of flavan-3-ol colonic metabolites: preliminary elucidation of urinary metabotypes. Eur J Nutr. 2019;58(4):1529–43. https://doi.org/10.1007/s00394-018-1683-4.
Article CAS PubMed Google Scholar
Manach C, Morand C, Gil-Izquierdo A, Bouteloup-Demange C, Rémésy C. Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice. Eur J Clin Nutr. 2003;57(2):235–42.
Article CAS PubMed Google Scholar
Corrêa TAF, Rogero MM, Hassimotto NMA, Lajolo FM. The two-way polyphenols-microbiota interactions and their effects on obesity and related metabolic diseases. Front Nutr. 2019;6:188.
Article PubMed PubMed Central Google Scholar
Ma G, Chen Y. Polyphenol supplementation benefits human health via gut microbiota: a systematic review via meta-analysis. J Funct Foods. 2020;66:103829.
Cani PD, Neyrinck AM, Fava F, Knauf C, Burcelin RG, Tuohy KM, et al. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia. 2007;50(11):2374–83. https://doi.org/10.1007/s00125-007-0791-0.
Article CAS PubMed Google Scholar
Liao ZL, Zeng BH, Wang W, Li GH, Wu F, Wang L, et al. Impact of the consumption of tea polyphenols on early atherosclerotic lesion formation and intestinal Bifidobacteria in high-fat-fed ApoE−/− mice. Front Nutr. 2016;3:42.
Article PubMed PubMed Central Google Scholar
Cases J, Romain C, Dallas C, Gerbi A, Rouanet JM. A 12-week randomized double-blind parallel pilot trial of Sinetrol XPur on body weight, abdominal fat, waist circumference, and muscle metabolism in overweight men. Int J Food Sci Nutr. 2015;66(4):471–7. https://doi.org/10.3109/09637486.2015.1042847.
Article CAS PubMed Google Scholar
Dallas C, Gerbi A, Elbez Y, Caillard P, Zamaria N, Cloarec M. Clinical study to assess the efficacy and safety of a citrus polyphenolic extract of red orange, grapefruit, and orange (Sinetrol-XPur) on weight management and metabolic parameters in healthy overweight individuals. Phytother Res. 2014;28(2):212–8. https://doi.org/10.1002/ptr.4981.
Article CAS PubMed Google Scholar
Muralidharan J, Romain C, Bresciani L, Mena P, Angelino D, Del RD, et al. Nutrikinetics and urinary excretion of phenolic compounds after a 16-week supplementation with a flavanone-rich ingredient. Food Funct. 2023;14(23):10506–19.
Article CAS PubMed Google Scholar
Brindani N, Mena P, Calani L, Benzie I, Choi SW, Brighenti F, et al. Synthetic and analytical strategies for the quantification of phenyl-γ-valerolactone conjugated metabolites in human urine. Mol Nutr Food Res. 2017;61(9):1700077. https://doi.org/10.1002/mnfr.201700077.
Lluch J, Servant F, Païssé S, Valle C, Valière S, Kuchly C, et al. The characterization of novel tissue microbiota using an optimized 16s metagenomic sequencing pipeline. PLoS One. 2015;10(11):e0142334. https://doi.org/10.1371/journal.pone.0142334.
Article CAS PubMed PubMed Central Google Scholar
Escudié F, Auer L, Bernard M, Mariadassou M, Cauquil L, Vidal K, et al. FROGS: find, rapidly, OTUs with galaxy solution. Bioinformatics. 2018;34(8):1287–94. https://doi.org/10.1093/bioinformatics/btx791.
Article CAS PubMed Google Scholar
Gruzdeva O, Borodkina D, Uchasova E, Dyleva Y, Barbarash O. Leptin resistance: underlying mechanisms and diagnosis. Diabetes Metab Syndr Obes. 2019;12:191.
Article CAS PubMed PubMed Central Google Scholar
Owecki M, Nikisch E, Miczke A, Pupek-Musialik D, Sowiski J. Leptin, soluble leptin receptors, free leptin index, and their relationship with insulin resistance and BMI: high normal BMI is the threshold for serum leptin increase in humans. Horm Metab Res. 2010;42(8):585–9. https://doi.org/10.1055/s-0030-1253422.
Article CAS PubMed Google Scholar
Wang X, Li D, Liu F, Cui Y, Li X. Dietary citrus and/or its extracts intake contributed to weight control: evidence from a systematic review and meta-analysis of 13 randomized clinical trials. Phytother Res. 2020;34(8):2006–22. https://doi.org/10.1002/ptr.6673.
Article CAS PubMed Google Scholar
Mollace V, Sacco I, Janda E, Malara C, Ventrice D, Colica C, et al. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. Fitoterapia. 2011;82(3):309–16.
Article CAS PubMed Google Scholar
Ren B, Qin W, Wu F, Wang S, Pan C, Wang L, et al. Apigenin and naringenin regulate glucose and lipid metabolism, and ameliorate vascular dysfunction in type 2 diabetic rats. Eur J Pharmacol. 2016;773:13–23.
留言 (0)