Massironi S, Sciola V, Peracchi M, Ciafardini C, Spampatti MP, Conte D (2008) Neuroendocrine tumors of the gastro-entero-pancreatic system. World J Gastroenterol 14(35):5377–5384

Article  PubMed  PubMed Central  Google Scholar 

Rindi G, Klimstra DS, Abedi-Ardekani B, Asa SL, Bosman FT, Brambilla E et al (2018) A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal. Mod Pathol 31(12):1770–1786

Article  PubMed  PubMed Central  Google Scholar 

Rindi G, Mete O, Uccella S, Basturk O, La Rosa S, Brosens LAA et al (2022) Overview of the 2022 WHO classification of neuroendocrine neoplasms. Endocr Pathol 33(1):115–154

Article  CAS  PubMed  Google Scholar 

Clift AK, Kidd M, Bodei L, Toumpanakis C, Baum RP, Oberg K et al (2020) Neuroendocrine neoplasms of the small bowel and pancreas. Neuroendocrinology 110(6):444–476

Article  CAS  PubMed  Google Scholar 

Massironi S (2024) The diagnostic challenges of functioning neuroendocrine tumors: balancing accuracy, availability, and personalized care. Expert Rev Endocrinol Metab 19(2):99–101

Article  CAS  PubMed  Google Scholar 

Das S, Dasari A, Epidemiology (2021) Incidence, and prevalence of neuroendocrine neoplasms: are there global differences? Curr Oncol Rep 23(4):43

Article  PubMed  PubMed Central  Google Scholar 

Lee MR, Harris C, Baeg KJ, Aronson A, Wisnivesky JP, Kim MK (2019) Incidence trends of Gastroenteropancreatic Neuroendocrine Tumors in the United States. Clin Gastroenterol Hepatol 17(11):2212–7e1

Article  PubMed  Google Scholar 

Dasari A, Shen C, Halperin D, Zhao B, Zhou S, Xu Y et al (2017) Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States. JAMA Oncol 3(10):1335–1342

Article  PubMed  PubMed Central  Google Scholar 

Thiis-Evensen E, Boyar Cetinkaya R (2023) Incidence and prevalence of neuroendocrine neoplasms in Norway 1993–2021. J Neuroendocrinol 35(4):e13264

Article  CAS  PubMed  Google Scholar 

Michael M, Thursfield V, Te Marvelde L, Kong G, Hicks RJ (2022) Incidence, prevalence, and survival trends for neuroendocrine neoplasms in Victoria, Australia, from 1982 to 2019: based on site, grade, and region. Asia Pac J Clin Oncol 18(5):e306–e17

Article  CAS  PubMed  Google Scholar 

Xu Z, Wang L, Dai S, Chen M, Li F, Sun J et al (2021) Epidemiologic trends of and factors Associated with overall survival for patients with gastroenteropancreatic neuroendocrine tumors in the United States. JAMA Netw Open 4(9):e2124750

Article  PubMed  PubMed Central  Google Scholar 

Rossi RE, Massironi S (2022) The Increasing Incidence of Neuroendocrine Neoplasms Worldwide: Current Knowledge and Open Issues. J Clin Med. 11. Switzerland

Feola T, Puliani G, Sesti F, Modica R, Centello R, Minotta R et al (2022) Risk factors for gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs): a three-centric case-control study. J Endocrinol Invest 45(4):849–857

Article  CAS  PubMed  Google Scholar 

Imbroisi Filho R, Ochioni AC, Esteves AM, Leandro JGB, Demaria TM, Sola-Penna M et al (2021) Western diet leads to aging-related tumorigenesis via activation of the inflammatory, UPR, and EMT pathways. Cell Death Dis 12(7):643

Article  CAS  PubMed  PubMed Central  Google Scholar 

Muscogiuri G, Barrea L, Cantone MC, Guarnotta V, Mazzilli R, Verde L et al (2022) Neuroendocrine tumors: a Comprehensive Review on Nutritional approaches. Cancers (Basel) 14:18

Article  Google Scholar 

Mentella MC, Scaldaferri F, Ricci C, Gasbarrini A, Miggiano GAD (2019) Cancer Mediterranean Diet: Rev Nutrients. ;11(9)

Maasberg S, Knappe-Drzikova B, Vonderbeck D, Jann H, Weylandt KH, Grieser C et al (2017) Malnutrition predicts clinical outcome in patients with neuroendocrine neoplasia. Neuroendocrinology 104(1):11–25

Article  CAS  PubMed  Google Scholar 

Clement D, van Leerdam ME, Tesselaar MET, Cananea E, Martin W, Weickert MO et al (2024) The global leadership into malnutrition criteria reveals a high percentage of malnutrition which influences overall survival in patients with gastroenteropancreatic neuroendocrine tumours. J Neuroendocrinol. :e13376

Clement D, Leerdam MEV, de Jong S, Weickert MO, Ramage JK, Tesselaar MET et al (2023) Prevalence of Sarcopenia and Impact on Survival in patients with metastatic gastroenteropancreatic neuroendocrine tumours. Cancers (Basel). ;15(3)

Clement D, Brown S, Leerdam MV, Tesselaar M, Ramage J, Srirajaskanthan R (2024) Sarcopenia and Neuroendocrine Neoplasms. Curr Oncol Rep 26(2):121–128

Article  PubMed  Google Scholar 

Capuozzo M, Celotto V, Landi L, Ferrara F, Sabbatino F, Perri F et al (2023) Beyond body size: Adiponectin as a key player in obesity-driven cancers. Nutr Cancer 75(10):1848–1862

Article  PubMed  Google Scholar 

Wells GA SB, O’Connell D The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-analyses. Ottawa: Ottawa Hospital Research Institute. p. http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp

Munn Z, Barker TH, Moola S, Tufanaru C, Stern C, McArthur A et al (2020) Methodological quality of case series studies: an introduction to the JBI critical appraisal tool. JBI Evid Synth 18(10):2127–2133

PubMed  Google Scholar 

Clement DS, Tesselaar ME, van Leerdam ME, Srirajaskanthan R, Ramage JK (2019) Nutritional and vitamin status in patients with neuroendocrine neoplasms. World J Gastroenterol 25(10):1171–1184

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barrea L, Altieri B, Muscogiuri G, Laudisio D, Annunziata G, Colao A et al (2018) Impact of nutritional status on gastroenteropancreatic neuroendocrine tumors (GEP-NET) aggressiveness. Nutrients. ;10(12)

Gallo M, Muscogiuri G, Pizza G, Ruggeri RM, Barrea L, Faggiano A et al (2019) The management of neuroendocrine tumours: a nutritional viewpoint. Crit Rev Food Sci Nutr 59(7):1046–1057

Article  PubMed  Google Scholar 

Qureshi SA, Burch N, Druce M, Hattersley JG, Khan S, Gopalakrishnan K et al (2016) Screening for malnutrition in patients with gastro-entero-pancreatic neuroendocrine tumours: a cross-sectional study. BMJ Open 6(5):e010765

Article  PubMed  PubMed Central  Google Scholar 

Borre M, Dam GA, Knudsen AW, Grønbaek H (2018) Nutritional status and nutritional risk in patients with neuroendocrine tumors. Scand J Gastroenterol 53(3):284–292

Article  PubMed  Google Scholar 

Pavel M, Gross DJ, Benavent M, Perros P, Srirajaskanthan R, Warner RRP et al (2018) Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial. Endocr Relat Cancer 25(3):309–322

Article  CAS  PubMed  PubMed Central  Google Scholar 

Romano E, Polici M, Marasco M, Lerose F, Dell’Unto E, Nardacci S et al (2024) Sarcopenia in patients with Advanced Gastrointestinal Well-differentiated neuroendocrine tumors. Nutrients. ;16(14)

Herrera-Martínez Y, Alzas Teomiro C, León Idougourram S, Molina Puertas MJ, Calañas Continente A, Serrano Blanch R et al (2021) Sarcopenia and Ghrelin System in the clinical outcome and prognosis of gastroenteropancreatic neuroendocrine neoplasms. Cancers (Basel). ;14(1)

Kessinger A, Lemon HM, Foley JF (1977) The glucagonoma syndrome and its management. J Surg Oncol 9(5):419–424

Article  CAS  PubMed  Google Scholar 

Rinzivillo M, De Felice I, Magi L, Annibale B, Panzuto F (2020) Occurrence of exocrine pancreatic insufficiency in patients with advanced neuroendocrine tumors treated with somatostatin analogs. Pancreatology 20(5):875–879

Article  CAS  PubMed  Google Scholar 

Lamarca A, McCallum L, Nuttall C, Barriuso J, Backen A, Frizziero M et al (2018) Somatostatin analogue-induced pancreatic exocrine insufficiency in patients with neuroendocrine tumors: results of a prospective observational study. Expert Rev Gastroenterol Hepatol 12(7):723–731

Article  CAS  PubMed  Google Scholar 

Marrache F, Vullierme MP, Roy C, El Assoued Y, Couvelard A, O’Toole D et al (2007) Arterial phase enhancement and body mass index are predictors of response to chemoembolisation for liver metastases of endocrine tumours. Br J Cancer 96(1):49–55

Article  CAS  PubMed  Google Scholar 

Ekeblad S, Skogseid B, Dunder K, Oberg K, Eriksson B (2008) Prognostic factors and survival in 324 patients with pancreatic endocrine tumor treated at a single institution. Clin Cancer Res 14(23):7798–7803

Article  CAS  PubMed  Google Scholar 

Lind A, Wängberg B, Ellegård L (2016) Vitamin D and vitamin B12 deficiencies are common in patients with midgut carcinoid (SI-NET). Eur J Clin Nutr 70(9):990–994

Article  CAS  PubMed  Google Scholar 

Chan DL, Clarke SJ, Engel A, Diakos CI, Pavlakis N, Roach PJ et al (2022) Computed tomography (CT)-defined Sarcopenia and myosteatosis are prevalent in patients with neuroendocrine neoplasms (NENs) treated with peptide receptor radionuclide therapy (PRRT). Eur J Clin