Alam M, Ahmad R, Rajabi H, Kufe D. MUC1-C induces the LIN28B→LET-7→HMGA2 axis to regulate relf-renewal in NSCLC. Mol Cancer Res. 2015;13:449–60.
Article CAS PubMed Google Scholar
Ali Hosseini Rad SM, Bavarsad MS, Arefian E, Jaseb K, Shahjahani M, Saki N. The role of microRNAs in Stemness of Cancer Stem cells. Oncol Rev. 2013;7:e8.
Article PubMed PubMed Central Google Scholar
An S, Shi J, Huang J, Li Z, Feng M, Cao G. HIF-1alpha-induced upregulation of m6A reader IGF2BP1 facilitates peripheral nerve injury recovery by enhancing SLC7A11 mRNA stabilization. Vitro Cell Dev-An. 2023;59:596–605.
Bai W, Xiao G, Xie G, Chen Z, Xu X, Zeng J et al. METTL3/IGF2BP1 influences the development of non-small-cell lung cancer by mediating m6A methylation modification of TRPV1. Thorac Cancer. 2024.
Basak A, Munschauer M, Lareau CA, Montbleau KE, Ulirsch JC, Hartigan CR, et al. Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation. Nat Genet. 2020;52:138–45.
Article CAS PubMed PubMed Central Google Scholar
Bell JL, Wachter K, Muhleck B, Pazaitis N, Kohn M, Lederer M, et al. Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression? Cell Mol Life Sci. 2013;70:2657–75.
Article CAS PubMed Google Scholar
Bernstein PL, Herrick DJ, Prokipcak RD, Ross J. Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant. Genes Dev. 1992;6:642–54.
Article CAS PubMed Google Scholar
Bley N, Schott A, Muller S, Misiak D, Lederer M, Fuchs T, et al. IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer. RNA Biol. 2021;18:391–403.
Article CAS PubMed Google Scholar
Boylan KL, Mische S, Li M, Marques G, Morin X, Chia W, et al. Motility screen identifies Drosophila IGF-II mRNA-binding protein–zipcode-binding protein acting in oogenesis and synaptogenesis. PLoS Genet. 2008;4:e36.
Article PubMed PubMed Central Google Scholar
Cai X, Chen Y, Man D, Yang B, Feng X, Zhang D, et al. RBM15 promotes hepatocellular carcinoma progression by regulating N6-methyladenosine modification of YES1 mRNA in an IGF2BP1-dependent manner. Cell Death Discov. 2021;7:315.
Article PubMed PubMed Central Google Scholar
Carmel MS, Kahane N, Oberman F, Miloslavski R, Sela-Donenfeld D, Kalcheim C, et al. A novel role for VICKZ proteins in maintaining epithelial integrity during embryogenesis. PLoS ONE. 2015;10:e0136408.
Article PubMed PubMed Central Google Scholar
Chambers CB, Gross J, Pratt K, Guo X, Byrnes C, Lee YT, et al. The mRNA-binding protein IGF2BP1 restores fetal hemoglobin in cultured erythroid cells from patients with beta-hemoglobin disorders. Mol Ther Methods Clin Dev. 2020;17:429–40.
Article CAS PubMed PubMed Central Google Scholar
Chen J, Zhang R, Lan J, Lin S, Li P, Gao J et al. IGF2BP1 significantly enhances translation efficiency of duck Hepatitis A Virus Type 1 without affecting viral replication. Biomolecules. 2019;9.
Chen M, Tian B, Hu G, Guo Y. METTL3-Modulated circUHRF2 promotes Colorectal Cancer Stemness and Metastasis through increasing DDX27 mRNA Stability by recruiting IGF2BP1. Cancers. 2023;15.
Cheng M, Si Y, Niu Y, Liu X, Li X, Zhao J, et al. High-throughput profiling of alpha interferon- and interleukin-28B-regulated microRNAs and identification of let-7s with anti-hepatitis C virus activity by targeting IGF2BP1. J Virol. 2013;87:9707–18.
Article CAS PubMed PubMed Central Google Scholar
Craig EA, Weber JD, Spiegelman VS. Involvement of the mRNA binding protein CRD-BP in the regulation of metastatic melanoma cell proliferation and invasion by hypoxia. J Cell Sci. 2012;125:5950–4.
Article CAS PubMed PubMed Central Google Scholar
Dagil R, Ball NJ, Ogrodowicz RW, Hobor F, Purkiss AG, Kelly G, et al. IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties. Nucleic Acids Res. 2019;47:4334–48.
Article CAS PubMed PubMed Central Google Scholar
Dai Y, Chen T, Ijaz H, Cho EH, Steinberg MH. SIRT1 activates the expression of fetal hemoglobin genes. Am J Hematol. 2017;92:1177–86.
Article CAS PubMed PubMed Central Google Scholar
de Vasconcellos JF, Tumburu L, Byrnes C, Lee YT, Xu PC, Li M, et al. IGF2BP1 overexpression causes fetal-like hemoglobin expression patterns in cultured human adult erythroblasts. Proc Natl Acad Sci U S A. 2017;114:E5664–72.
Article PubMed PubMed Central Google Scholar
Degrauwe N, Suva ML, Janiszewska M, Riggi N, Stamenkovic I. IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer. Genes Dev. 2016;30:2459–74.
Article CAS PubMed PubMed Central Google Scholar
Dhamdhere MR, Gowda CP, Singh V, Liu Z, Carruthers N, Grant CN, et al. IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis. Oncogene. 2023;42:1558–71.
Article CAS PubMed PubMed Central Google Scholar
Ding L, Wu H, Wang Y, Li Y, Liang Z, Xia X, et al. m6A reader Igf2bp1 regulates the inflammatory responses of Microglia by stabilizing Gbp11 and cp mRNAs. Front Immunol. 2022;13:872252.
Article CAS PubMed PubMed Central Google Scholar
Dong G, Yu J, Shan G, Su L, Yu N, Yang S. N6-Methyladenosine methyltransferase METTL3 promotes angiogenesis and atherosclerosis by upregulating the JAK2/STAT3 pathway via m6A reader IGF2BP1. Front cell Dev Biology. 2021;9:731810.
Donnelly CJ, Willis DE, Xu M, Tep C, Jiang C, Yoo S, et al. Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity. EMBO J. 2011;30:4665–77.
Article CAS PubMed PubMed Central Google Scholar
Doyle GA, Bourdeau-Heller JM, Coulthard S, Meisner LF, Ross J. Amplification in human breast cancer of a gene encoding a c-myc mRNA-binding protein. Cancer Res. 2000;60:2756–9.
Du X, Zhou P, Zhang H, Peng H, Mao X, Liu S, et al. Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma. Cell Death Dis. 2023;14:301.
Article CAS PubMed PubMed Central Google Scholar
Elcheva IA, Wood T, Chiarolanzio K, Chim B, Wong M, Singh V, et al. RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1. Leukemia. 2020;34:1354–63.
Article CAS PubMed Google Scholar
Elcheva IA, Gowda CP, Bogush D, Gornostaeva S, Fakhardo A, Sheth N, et al. IGF2BP family of RNA-binding proteins regulate innate and adaptive immune responses in cancer cells and tumor microenvironment. Front Immunol. 2023;14:1224516.
Article PubMed PubMed Central Google Scholar
Eom T, Antar LN, Singer RH, Bassell GJ. Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses. J Neurosci. 2003;23:10433–44.
Article CAS PubMed PubMed Central Google Scholar
Fabrizio JJ, Hickey CA, Stabrawa C, Meytes V, Hutter JA, Talbert C, et al. Imp (IGF-II mRNA-binding protein) is expressed during spermatogenesis in Drosophila melanogaster. Fly (Austin). 2008;2:47–52.
Fakhraldeen SA, Clark RJ, Roopra A, Chin EN, Huang W, Castorino J, et al. Two isoforms of the RNA binding protein, Coding Region determinant-binding protein (CRD-BP/IGF2BP1), are expressed in breast epithelium and support clonogenic growth of breast tumor cells. J Biol Chem. 2015;290:13386–400.
留言 (0)