Alberts B, Wilson JH, Hunt T. Molecular biology of the cell. 5th ed. New York: Garland Science; 2008. xxxiii, 1601, 90 p. p.
Skalska L, Beltran-Nebot M, Ule J, Jenner RG. Regulatory feedback from nascent RNA to chromatin and transcription. Nat Rev Mol Cell Biol. 2017;18(5):331–7.
Article CAS PubMed Google Scholar
Van Nostrand EL, Freese P, Pratt GA, Wang X, Wei X, Xiao R, et al. A large-scale binding and functional map of human RNA-binding proteins. Nature. 2020;583(7818):711–9.
Article PubMed PubMed Central Google Scholar
Cooper TA, Wan L, Dreyfuss G. RNA and disease. Cell. 2009;136(4):777–93.
Article CAS PubMed PubMed Central Google Scholar
Gebauer F, Schwarzl T, Valcarcel J, Hentze MW. RNA-binding proteins in human genetic disease. Nat Rev Genet. 2021;22(3):185–98.
Article CAS PubMed Google Scholar
Consortium EP. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489(7414):57–74.
Frith MC, Pheasant M, Mattick JS. The amazing complexity of the human transcriptome. Eur J Hum Genet. 2005;13(8):894–7.
Article CAS PubMed Google Scholar
International Human Genome Sequencing C. Finishing the euchromatic sequence of the human genome. Nature. 2004;431(7011):931–45.
Nurk S, Koren S, Rhie A, Rautiainen M, Bzikadze AV, Mikheenko A, et al. The complete sequence of a human genome. Science. 2022;376(6588):44–53.
Article CAS PubMed PubMed Central Google Scholar
Christmas MJ, Kaplow IM, Genereux DP, Dong MX, Hughes GM, Li X, et al. Evolutionary constraint and innovation across hundreds of placental mammals. Science. 2023;380(6643):eabn3943.
Article CAS PubMed PubMed Central Google Scholar
Galeota-Sprung B, Sniegowski P, Ewens W. Mutational load and the functional fraction of the Human Genome. Genome Biol Evol. 2020;12(4):273–81.
Article PubMed PubMed Central Google Scholar
Meader S, Ponting CP, Lunter G. Massive turnover of functional sequence in human and other mammalian genomes. Genome Res. 2010;20(10):1335–43.
Article CAS PubMed PubMed Central Google Scholar
Pheasant M, Mattick JS. Raising the estimate of functional human sequences. Genome Res. 2007;17(9):1245–53.
Article CAS PubMed Google Scholar
Leypold NA, Speicher MR. Evolutionary conservation in noncoding genomic regions. Trends Genet. 2021;37(10):903–18.
Article CAS PubMed Google Scholar
Pang KC, Frith MC, Mattick JS. Rapid evolution of noncoding RNAs: lack of conservation does not mean lack of function. Trends Genet. 2006;22(1):1–5.
Article CAS PubMed Google Scholar
Kutter C, Brown GD, Goncalves A, Wilson MD, Watt S, Brazma A, et al. Pol III binding in six mammals shows conservation among amino acid isotypes despite divergence among tRNA genes. Nat Genet. 2011;43(10):948–55.
Article CAS PubMed PubMed Central Google Scholar
Kutter C, Watt S, Stefflova K, Wilson MD, Goncalves A, Ponting CP, et al. Rapid turnover of long noncoding RNAs and the evolution of gene expression. PLoS Genet. 2012;8(7):e1002841.
Article CAS PubMed PubMed Central Google Scholar
Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, et al. Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2002;99(24):15524–9.
Article CAS PubMed PubMed Central Google Scholar
Huppertz I, Perez-Perri JI, Mantas P, Sekaran T, Schwarzl T, Russo F, et al. Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation. Mol Cell. 2022;82(14):2666–80. e11.
Article CAS PubMed Google Scholar
Kim J, Piao HL, Kim BJ, Yao F, Han Z, Wang Y, et al. Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Nat Genet. 2018;50(12):1705–15.
Article CAS PubMed PubMed Central Google Scholar
Rom A, Melamed L, Gil N, Goldrich MJ, Kadir R, Golan M, et al. Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability. Nat Commun. 2019;10(1):5092.
Article PubMed PubMed Central Google Scholar
Sommerauer C, Kutter C. Noncoding RNAs and RNA-binding proteins: emerging governors of liver physiology and metabolic diseases. Am J Physiol Cell Physiol. 2022;323(4):C1003–17.
Article CAS PubMed Google Scholar
Sondergaard JN, Sommerauer C, Atanasoai I, Hinte LC, Geng K, Guiducci G, et al. CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism. Gut. 2022;71(10):2081–92.
Article CAS PubMed Google Scholar
Aviran S, Incarnato D. Computational approaches for RNA structure ensemble deconvolution from structure probing data. J Mol Biol. 2022;434(18):167635.
Article CAS PubMed Google Scholar
Morandi E, van Hemert MJ, Incarnato D. SHAPE-guided RNA structure homology search and motif discovery. Nat Commun. 2022;13(1):1722.
Article CAS PubMed PubMed Central Google Scholar
Spitale RC, Incarnato D. Probing the dynamic RNA structurome and its functions. Nat Rev Genet. 2023;24(3):178–96.
Article CAS PubMed Google Scholar
Gao W, Yang A, Rivas E. Thirteen dubious ways to detect conserved structural RNAs. IUBMB Life. 2023;75(6):471–92.
Article CAS PubMed Google Scholar
Hentze MW, Castello A, Schwarzl T, Preiss T. A brave new world of RNA-binding proteins. Nat Rev Mol Cell Biol. 2018;19(5):327–41.
Article CAS PubMed Google Scholar
Lunde BM, Moore C, Varani G. RNA-binding proteins: modular design for efficient function. Nat Rev Mol Cell Biol. 2007;8(6):479–90.
Article CAS PubMed PubMed Central Google Scholar
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, et al. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell. 2012;149(6):1393–406.
Article CAS PubMed Google Scholar
Gerstberger S, Hafner M, Tuschl T. A census of human RNA-binding proteins. Nat Rev Genet. 2014;15(12):829–45.
留言 (0)