Travis, W. D., Brambilla, E. & Riely, G. J. New pathologic classification of lung cancer: relevance for clinical practice and clinical trials. J. Clin. Oncol. 31, 992–1001 (2013).
Article CAS PubMed Google Scholar
World Health Organization. WHO Global Report on Trends in Prevalence of Tobacco Use 2000–2025, fourth edition (WHO, 2021).
Akhtar-Danseh, G. G., Akhtar-Danesh, N. & Finley, C. Uptake and survival effects of minimally invasive surgery for lung cancer: a population-based study. Eur. J. Surg. Oncol. 47, 1791–1796 (2021).
Bucknell, N. W. et al. Avoiding toxicity with lung radiation therapy: an IASLC perspective. J. Thorac. Oncol. 17, 961–973 (2022).
Article CAS PubMed Google Scholar
Uprety, D. & Surapaneni, M. Lung cancer management in low and middle-income countries—current challenges and potential solutions. Int. J. Cancer Care Deliv. https://doi.org/10.53876/001c.73042 (2023).
Bray, F. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 74, 229–263 (2024).
WHO. Cancer Today, Lung fact sheet. WHO https://gco.iarc.who.int/media/globocan/factsheets/cancers/15-trachea-bronchus-and-lung-fact-sheet.pdf (2022).
Siegel, R. L., Miller, K. D., Wagle, N. S. & Jemal, A. Cancer statistics, 2023. CA Cancer J. Clin. 73, 17–48 (2023).
Wang, Y. et al. Survival trends among patients with metastatic non-small cell lung cancer before and after the approval of immunotherapy in the United States: a Surveillance, Epidemiology, and End Results database-based study. Cancer https://doi.org/10.1002/cncr.35476 (2024).
Article PubMed PubMed Central Google Scholar
Howlader, N. et al. The effect of advances in lung-cancer treatment on population mortality. N. Engl. J. Med. 383, 640–649 (2020). The first epidemiological data to show an effect of modern treatment strategies on outcome in lung cancer.
Article CAS PubMed PubMed Central Google Scholar
Santucci, C. et al. European cancer mortality predictions for the year 2024 with focus on colorectal cancer. Ann. Oncol. 35, 308–316 (2024).
Article CAS PubMed Google Scholar
MacRosty, C. R. & Rivera, M. P. Lung cancer in women: a modern epidemic. Clin. Chest Med. 41, 53–65 (2020).
Cancer Stat Facts: Lung and Bronchus Cancer https://seer.cancer.gov/statfacts/html/lungb.html (SEER, accessed 2 September 2024).
Nicholson, A. G. et al. The 2021 WHO classification of lung tumors: impact of advances since 2015. J. Thorac. Oncol. 17, 362–387 (2022).
Travis, W. D. et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma. J. Thorac. Oncol. 6, 244–285 (2011).
Article PubMed PubMed Central Google Scholar
Devarakonda, S. et al. Genomic profiling of lung adenocarcinoma in never-smokers. J. Clin. Oncol. 39, 3747–3758 (2021).
Article CAS PubMed PubMed Central Google Scholar
Barta, J. A., Powell, C. A. & Wisnivesky, J. P. Global epidemiology of lung cancer. Ann. Glob. Health 85, 8 (2019).
Article PubMed PubMed Central Google Scholar
Malhotra, J., Malvezzi, M., Negri, E., La Vecchia, C. & Boffetta, P. Risk factors for lung cancer worldwide. Eur. Respir. J. 48, 889–902 (2016).
Fares, A. F. et al. Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies. Lancet Public Health 8, e691–e700 (2023).
Article PubMed PubMed Central Google Scholar
Bracken-Clarke, D. et al. Vaping and lung cancer—a review of current data and recommendations. Lung Cancer 153, 11–20 (2021).
Betser, L. et al. Cannabis use and lung cancer: time to stop overlooking the problem? Eur. Respir. J. 57, 2004132 (2021).
Article CAS PubMed Google Scholar
Lariscy, J. T., Hummer, R. A. & Rogers, R. G. Lung cancer mortality among never-smokers in the United States: estimating smoking-attributable mortality with nationally representative data. Ann. Epidemiol. 45, 5–11 (2020).
Article PubMed PubMed Central Google Scholar
Díaz-Gay, M. et al. The mutagenic forces shaping the genomic landscape of lung cancer in never smokers. Preprint at medRxiv https://doi.org/10.1101/2024.05.15.24307318 (2024).
Hill, W. et al. Lung adenocarcinoma promotion by air pollutants. Nature 616, 159–167 (2023).
Article CAS PubMed PubMed Central Google Scholar
Arrieta, O. et al. Facing an un-met need in lung cancer screening: the never smokers. Crit. Rev. Oncol. Hematol. 202, 104436 (2024).
WHO. Air pollution. WHO https://www.who.int/news-room/fact-sheets/detail/household-air-pollution-and-health (2023).
Madas, B. G., Boei, J., Fenske, N., Hofmann, W. & Mezquita, L. Effects of spatial variation in dose delivery: what can we learn from radon-related lung cancer studies? Radiat. Environ. Biophys. 61, 561–577 (2022).
Article CAS PubMed PubMed Central Google Scholar
Oxnard, G. R., Nguyen, K. S. & Costa, D. B. Germline mutations in driver oncogenes and inherited lung cancer risk independent of smoking history. J. Natl Cancer Inst. 106, djt361 (2014).
Mezquita, L. et al. High prevalence of somatic oncogenic driver alterations in patients with NSCLC and Li-Fraumeni syndrome. J. Thorac. Oncol. 15, 1232–1239 (2020).
Article CAS PubMed Google Scholar
Carrot-Zhang, J. et al. Genetic ancestry contributes to somatic mutations in lung cancers from admixed Latin American populations. Cancer Discov. 11, 591–598 (2021).
Article CAS PubMed Google Scholar
LoPiccolo, J., Gusev, A., Christiani, D. C. & Jänne, P. A. Lung cancer in patients who have never smoked—an emerging disease. Nat. Rev. Clin. Oncol. 21, 121–146 (2024).
Article PubMed PubMed Central Google Scholar
Kotton, D. N. & Fine, A. Lung stem cells. Cell Tissue Res. 331, 145–156 (2008).
Giangreco, A., Groot, K. R. & Janes, S. M. Lung cancer and lung stem cells: strange bedfellows? Am. J. Respir. Crit. Care Med. 175, 547–553 (2007).
Willis, R. A. Pathology of Tumours. 4th edn (Butterworths, 1967).
Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646–674 (2011). A review providing an explanation of driving factors and conditions for cancer evolution.
Article CAS PubMed Google Scholar
Hanahan, D. Hallmarks of cancer: new dimensions. Cancer Discov. 12, 31–46 (2022). An update of the previous overview (ref. 35) in 2011.
Article CAS PubMed Google Scholar
WHO Classification of Tumours Editorial Board. Thoracic Tumours, WHO Classification of Tumours 5th edn, Vol. 5 (WHO, 2021).
Samet, J. M. Carcinogenesis and lung cancer: 70 years of progress and more to come. Carcinogenesis 41, 1309–1317 (2020).
Article CAS PubMed Google Scholar
Kerr, K. M. in Molecular Pathology of Lung Cancer (eds. Cagle, P. T. et al.) 35–52 (Springer, 2012). A key overview of the molecular classification of lung cancer.
Venkatesan, S. & Swanton, C. Tumor evolutionary principles
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