Bhatt VR, Wichman C, Al-Kadhimi ZS, Koll TT, Fisher AL, Mahato RI, et al. Integrating geriatric assessment and genetic profiling to personalize therapy selection in older adults with acute myeloid leukemia. J Geriatr Oncol. 2022;13(6):871–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Min G-J, Cho B-S, Park S-S, Park S, Jeon Y-W, Shin S-H, et al. Geriatric assessment predicts nonfatal toxicities and survival for intensively treated older adults with AML. Blood. 2022;139(11):1646–58.

Article  CAS  PubMed  Google Scholar 

Ritchie EK, Klepin HD, Storrick E, Major B, Le-Rademacher J, Wadleigh M, et al. Geriatric assessment for older adults receiving less-intensive therapy for acute myeloid leukemia: report of CALGB 361101. Blood Adv. 2022;6(12):3812–20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Pardee TS, et al. Geriatric assessment predicts survival for older adults receiving induction chemotherapy for acute myelogenous leukemia. Blood. 2013;121(21):4287–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hupfer V, Grishina O, Schmoor C, Schlenk RF, Salih HR, Crysandt M, et al. Validation of a frailty score predicting survival of elderly, non-Fit AML patients receiving hypomethylating therapy: results of the decider trial. Blood. 2018;132(Suppl 1):720.

Article  Google Scholar 

Saad M, Loh KP, Tooze JA, Pardee TS, Ellis LR, Powell BL, et al. Geriatric assessment and survival among older adults receiving postremission therapy for acute myeloid leukemia. Blood. 2020;136(23):2715–9.

Article  PubMed  PubMed Central  Google Scholar 

Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Ellis LR, et al. The feasibility of inpatient geriatric assessment for older adults receiving induction chemotherapy for acute myelogenous leukemia. J Am Geriatr Soc. 2011;59(10):1837–46.

Article  PubMed  PubMed Central  Google Scholar 

Bhatt VR. Advances and unanswered questions in management of acute myeloid leukemia in older adults: a glimpse into the future. J Geriatr Oncol. 2021;12(6):980–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhatt VR. Understanding patients’ values and priorities in selecting cancer treatments: developing a therapy preference scale. J Geriatr Oncol. 2019;10(5):677–9.

Article  PubMed  Google Scholar 

Richardson DR, Crossnohere NL, Seo J, Estey E, O’Donoghue B, Smith BD, et al. Age at diagnosis and patient preferences for treatment outcomes in AML: a discrete choice experiment to explore meaningful benefits. Cancer Epidemiol Biomarkers Prev. 2020;29(5):942–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhatt VR, Dhakal P, Wichman CS, Pozehl B. Development and validation of the therapy preference scale to understand patients systemic cancer treatment preferences. Future Oncol. 2021;17(1):37–44.

Article  CAS  PubMed  Google Scholar 

Dhakal P, Wichman CS, Pozehl B, Weaver M, Fisher AL, Vose J, et al. Preferences of adults with cancer for systemic cancer treatment: do preferences differ based on age? Future Oncol. 2022;18(3):311–21.

Article  CAS  PubMed  Google Scholar 

Dhakal P, Wichman C, Pozehl B, Mahato K, Bhatt VR. Preferences of patients with acute myeloid leukemia and other myeloid malignancies on cancer treatment: effect of patient- and treatment-characteristics? Blood. 2023;142(Supplement 1):3731.

Article  Google Scholar 

Bhatt VR, Shostrom V, Gundabolu K, Armitage JO. Utilization of initial chemotherapy for newly diagnosed acute myeloid leukemia in the United States. Blood Adv. 2018;2(11):1277–82.

Article  PubMed  PubMed Central  Google Scholar 

Bhatt VR, Wichman C, Koll TT, Fisher A, Wildes TM, Haddadin M, et al. Use of geriatric assessment and genetic profiling to personalize selection of intensive versus low intensity chemotherapy in older adults with acute myeloid leukemia (AML): final results of a phase II trial. Blood. 2023;142(1):4265.

Article  Google Scholar 

Bhatt VR. Personalizing therapy for older adults with acute myeloid leukemia: role of geriatric assessment and genetic profiling. Cancer Treat Rev. 2019;75:52–61.

Article  PubMed  Google Scholar 

Artz A, Logan BR, Saber W, Geller N, Bellach A, Kou J, et al. The composite health risk assessment model (CHARM) to predict 1-year non-relapse mortality (NRM) among older recipients of allogeneic transplantation: a prospective BMT-CTN study 1704. Blood. 2023;142(Supplement 1):109.

Article  Google Scholar 

Bhatt VR, Gundabolu K, Koll T, Maness LJ. Initial therapy for acute myeloid leukemia in older patients: principles of care. Leuk Lymphoma. 2018;59(1):29–41.

Article  PubMed  Google Scholar 

Bhatt VR, Uy GL, Klepin HD. Determining treatment tolerance and fitness for intensive chemotherapy in older adults with AML: a call to action. Blood. 2024;143(6):483–7.

Article  CAS  PubMed  Google Scholar 

Bhatt VR, Wichman C, Koll TT, Fisher AL, Wildes TM, Berger A, et al. Longitudinal changes in cognitive and physical function and health-related quality of life in older adults with acute myeloid leukemia. J Geriatr Oncol. 2024;15(1):101676.

Article  CAS  PubMed  Google Scholar 

Dhakal P, Shostrom V, Al-Kadhimi ZS, Maness LJ, Gundabolu K, Bhatt VR. Usefulness of charlson comorbidity index to predict early mortality and overall survival in older patients with acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2020;20(12):804–12.

Article  PubMed  PubMed Central  Google Scholar 

Bhatt VR, Shostrom V, Holstein SA, Al-Kadhimi ZS, Maness LJ, Berger A, et al. Survival of older adults with newly diagnosed acute myeloid leukemia: effect of using multiagent versus single-agent chemotherapy. Clin Lymphoma Myeloma Leuk. 2020;20(5):e239–58.

Article  PubMed  PubMed Central  Google Scholar 

Klepin HD, Ritchie EK, Sanford BL, Marcucci G, Zhao W, Geyer SM, et al. Feasibility of geriatric assessment for older adults with acute myeloid leukemia (AML) receiving intensive chemotherapy on a cooperative group trial: CALGB 361006 (Alliance). J Clin Oncol. 2014;32(15_Suppl):7102.

Article  Google Scholar 

Bhatt VR. Cancer in older adults: understanding cause and effects of chemotherapy-related toxicities. Future Oncol. 2019;15(22):2557–60.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhatt VR, Ulrich AM, Uy GL, Stone RM, Stock W, Ojelabi MO, et al. Outcomes of older adults with AML treated in community versus academic centers: an analysis of alliance trials. JCO Oncol Pract. 2023;19(6):e877–91.

Article  PubMed  PubMed Central  Google Scholar 

Bhatt VR, Shostrom V, Giri S, Gundabolu K, Monirul Islam KM, Appelbaum FR, et al. Early mortality and overall survival of acute myeloid leukemia based on facility type. Am J Hematol. 2017;92(8):764–71.

Article  PubMed  Google Scholar 

Hurria A, Mohile S, Gajra A, Klepin H, Muss H, Chapman A, et al. Validation of a prediction tool for chemotherapy toxicity in older adults with cancer. J Clin Oncol. 2016;34(20):2366–71.

Article  PubMed  PubMed Central  Google Scholar 

Mohile SG, Dale W, Somerfield MR, Schonberg MA, Boyd CM, Burhenn PS, et al. Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: ASCO guideline for geriatric oncology. J Clin Oncol. 2018;36(22):2326–47.

Article  PubMed  PubMed Central  Google Scholar 

Dale W, Klepin HD, Williams GR, Alibhai SMH, Bergerot C, Brintzenhofeszoc K, et al. Practical assessment and management of vulnerabilities in older patients receiving systemic cancer therapy: ASCO guideline update. J Clin Oncol. 2023;41(26):4293–312.

Article  PubMed  Google Scholar 

Diaz FC, Hamparsumian A, Loh KP, Verduzco-Aguirre H, Abdallah M, Williams GR, et al. Geriatric oncology: a 5-year strategic plan. Am Soc Clin Oncol Educ Book. 2024;44(3):e100044.

Article  PubMed  Google Scholar 

Ginsburg GS, Picard RW, Friend SH. Key issues as wearable digital health technologies enter clinical care. N Engl J Med. 2024;390(12):1118–27.