S. Jones, An overview of the basic helix-loop-helix proteins. Genome Biol. 5(6), 226 (2004)
Article PubMed PubMed Central Google Scholar
R.J. Kewley, M.L. Whitelaw, A. Chapman-Smith, The mammalian basic helix-loop-helix/PAS family of transcriptional regulators. Int. J. Biochem. Cell. Biol. 36(2), 189–204 (2004)
Article CAS PubMed Google Scholar
R.L. Davis, D.L. Turner, Vertebrate hairy and enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning. Oncogene. 20(58), 8342–8357 (2001)
Article CAS PubMed Google Scholar
C.R. Vinson, K.C. Garcia, Molecular model for DNA recognition by the family of basic-helix-loop-helix-zipper proteins. New. Biol. 4(4), 396–403 (1992)
K. Fujimoto, H. Hamaguchi, T. Hashiba, T. Nakamura, T. Kawamoto, F. Sato et al., Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements. Int. J. Mol. Med. 19(6), 925–932 (2007)
K. Fujimoto, M. Shen, M. Noshiro, K. Matsubara, S. Shingu, K. Honda et al., Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins. Biochem. Biophys. Res. Commun. 280(1), 164–171 (2001)
Article CAS PubMed Google Scholar
H. Hamaguchi, K. Fujimoto, T. Kawamoto, M. Noshiro, K. Maemura, N. Takeda et al., Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system. Biochem. J. 382(Pt 1), 43–50 (2004)
Article CAS PubMed PubMed Central Google Scholar
M.J. Rossner, J. Dorr, P. Gass, M.H. Schwab, K.A. Nave, SHARPs: mammalian enhancer-of-split- and hairy-related proteins coupled to neuronal stimulation. Mol. Cell. Neurosci. 10(3–4), 460–475 (1997)
Article CAS PubMed Google Scholar
S. Azmi, H. Sun, A. Ozog, R. Taneja, mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression. J. Biol. Chem. 278(22), 20098–20109 (2003)
Article CAS PubMed Google Scholar
K. Yamada, K. Miyamoto, Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their gene expressions are regulated by multiple extracellular stimuli. Front. Biosci. 10, 3151–3171 (2005)
Article CAS PubMed Google Scholar
Y. Cho, M. Noshiro, M. Choi, K. Morita, T. Kawamoto, K. Fujimoto et al., The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors. Mol. Pharmacol. 76(6), 1360–1369 (2009)
Article CAS PubMed Google Scholar
F. Sato, T. Kawamoto, K. Fujimoto, M. Noshiro, K.K. Honda, S. Honma et al., Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1. Eur. J. Biochem. 271(22), 4409–4419 (2004)
Article CAS PubMed Google Scholar
J.H. Chuang, A.A. Yarmishyn, D.K. Hwang, C.C. Hsu, M.L. Wang, Y.P. Yang et al., Expression profiling of cell-intrinsic regulators in the process of differentiation of human iPSCs into retinal lineages. Stem Cell. Res. Ther. 9(1), 140 (2018)
Article CAS PubMed PubMed Central Google Scholar
Z.H. Zhou, B. Wang, X.B. Cheng, X.E. Zhang, J. Tang, W.J. Tang et al., Roles of SHARP1 in thyroid cancer. Mol. Med. Rep. 13(6), 5365–5371 (2016)
Article CAS PubMed Google Scholar
T. Kawamoto, M. Noshiro, F. Sato, K. Maemura, N. Takeda, R. Nagai et al., A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation. Biochem. Biophys. Res. Commun. 313(1), 117–124 (2004)
Article CAS PubMed Google Scholar
U.K. Bhawal, F. Sato, Y. Arakawa, K. Fujimoto, T. Kawamoto, K. Tanimoto et al., Basic helix-loop-helix transcription factor DEC1 negatively regulates cyclin D1. J. Pathol. 224(3), 420–429 (2011)
Article CAS PubMed Google Scholar
M.P. Butler, S. Honma, T. Fukumoto, T. Kawamoto, K. Fujimoto, M. Noshiro et al., Dec1 and Dec2 expression is disrupted in the suprachiasmatic nuclei of clock mutant mice. J. Biol. Rhythms. 19(2), 126–134 (2004)
Article CAS PubMed Google Scholar
P. Bragado, Y. Estrada, F. Parikh, S. Krause, C. Capobianco, H.G. Farina et al., TGF-beta2 dictates disseminated tumour cell fate in target organs through TGF-beta-RIII and p38alpha/beta signalling. Nat. Cell. Biol. 15(11), 1351–1361 (2013)
Article CAS PubMed PubMed Central Google Scholar
J. Olkkonen, V.P. Kouri, J. Hynninen, Y.T. Konttinen, J. Mandelin, Differentially expressed in chondrocytes 2 (DEC2) increases the expression of IL-1beta and is abundantly Present in Synovial membrane in rheumatoid arthritis. PLoS One. 10(12), e0145279 (2015)
Article PubMed PubMed Central Google Scholar
K. Miyazaki, T. Kawamoto, K. Tanimoto, M. Nishiyama, H. Honda, Y. Kato, Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J. Biol. Chem. 277(49), 47014–47021 (2002)
Article CAS PubMed Google Scholar
N. Ozaki, M. Noshiro, T. Kawamoto, A. Nakashima, K. Honda, U. Fukuzaki-Dohi et al., Regulation of basic helix-loop-helix transcription factors Dec1 and Dec2 by RORalpha and their roles in adipogenesis. Genes Cells. 17(2), 109–121 (2012)
Article CAS PubMed Google Scholar
M. Adorno, M. Cordenonsi, M. Montagner, S. Dupont, C. Wong, B. Hann et al., A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell. 137(1), 87–98 (2009)
Article CAS PubMed Google Scholar
S. Inaguma, M. Riku, M. Hashimoto, H. Murakami, S. Saga, H. Ikeda et al., GLI1 interferes with the DNA mismatch repair system in pancreatic cancer through BHLHE41-mediated suppression of MLH1. Cancer Res. 73(24), 7313–7323 (2013)
Article CAS PubMed Google Scholar
X.O. Yang, P. Angkasekwinai, J. Zhu, J. Peng, Z. Liu, R. Nurieva et al., Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment. Nat. Immunol. 10(12), 1260–1266 (2009)
Article CAS PubMed PubMed Central Google Scholar
V. Lecomte, E. Meugnier, V. Euthine, C. Durand, D. Freyssenet, G. Nemoz et al., A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation. Mol. Cell. Biol. 30(5), 1182–1198 (2010)
Article CAS PubMed Google Scholar
H. Oike, K. Nagai, T. Fukushima, N. Ishida, M. Kobori, Feeding cues and injected nutrients induce acute expression of multiple clock genes in the mouse liver. PLoS One. 6(8), e23709 (2011)
Article CAS PubMed PubMed Central Google Scholar
K. Takagi, K. Asano, A. Haneishi, M. Ono, Y. Komatsu, T. Yamamoto et al., Insulin stimulates the expression of the SHARP-1 gene via multiple signaling pathways. Horm. Metab. Res. 46(6), 397–403 (2014)
Article CAS PubMed Google Scholar
L. Zawel, J. Yu, C.J. Torrance, S. Markowitz, K.W. Kinzler, B. Vogelstein et al., DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities. Proc. Natl. Acad. Sci. U S A 99(5), 2848–2853 (2002)
Article CAS PubMed PubMed Central Google Scholar
A.V. Ivanova, S.V. Ivanov, X. Zhang, V.N. Ivanov, O.A. Timofeeva, M.I. Lerman, STRA13 interacts with STAT3 and modulates transcription of STAT3-dependent targets. J. Mol. Biol. 340(4), 641–653 (2004)
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