Goldenzweig A, Fleishman SJ. Principles of protein stability and their application in computational design. Annu Rev Biochem. 2018;87:105–29.

Article  CAS  PubMed  Google Scholar 

Taverna DM, Goldstein RA. Why are proteins marginally stable? Proteins Struct Funct Bioinform. 2002;46(1):105–9.

Article  CAS  Google Scholar 

Dobson CM, Šali A, Karplus M. Protein folding: a perspective from theory and experiment. Angew Chem Int Ed. 1998;37(7):868–93.

Article  Google Scholar 

Louros N, Schymkowitz J, Rousseau F. Mechanisms and pathology of protein misfolding and aggregation. Nat Rev Mol Cell Biol. 2023;24(12):912–33.

Article  CAS  PubMed  Google Scholar 

Cheng MY, Hartl FU, Martin J, Pollock RA, Kalousek F, Neuper W, et al. Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature. 1989;337(6208):620–5.

Article  CAS  PubMed  Google Scholar 

Ostermann J, Horwich AL, Neupert W, Hartl FU. Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis. Nature. 1989;341(6238):125–30.

Article  CAS  PubMed  Google Scholar 

Kim YE, Hipp MS, Bracher A, Hayer-Hartl M, Ulrich HF. Molecular chaperone functions in protein folding and proteostasis. Annu Rev Biochem. 2013;82:323–55.

Article  CAS  PubMed  Google Scholar 

Horwich AL. Chaperonin-mediated protein folding. J Biol Chem. 2013;288(33):23622–32.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tian G, Vainberg IE, Tap WD, Lewis SA, Cowan NJ. Specificity in chaperonin-mediated protein folding. Nature. 1995;375(6528):250–3.

Article  CAS  PubMed  Google Scholar 

Hartl FU, Bracher A, Hayer-Hartl M. Molecular chaperones in protein folding and proteostasis. Nature. 2011;475(7356):324–32.

Article  CAS  PubMed  Google Scholar 

Feder ME, Hofmann GE. Heat-shock proteins, molecular chaperones, aand the stress response: evolutionary and ecological physiology. Annu Rev Physiol. 1999;61:243–82.

Article  CAS  PubMed  Google Scholar 

Saibil H. Chaperone machines for protein folding, unfolding and disaggregation. Nat Rev Mol Cell Biol. 2013;14(10):630–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hendrick JP, Hartl F-U. Molecular chaperone functions of heat-shock proteins. Annu Rev Biochem. 1993;62:349–84.

Article  CAS  PubMed  Google Scholar 

Ritossa F. A new puffing pattern induced by temperature shock and DNP in drosophila. Experientia. 1962;18(12):571–3.

Article  CAS  Google Scholar 

Tissiéres A, Mitchell HK, Tracy UM. Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs. J Mol Biol. 1974;84(3):389–98.

Article  PubMed  Google Scholar 

Richter K, Haslbeck M, Buchner J. The heat shock response: life on the verge of death. Mol Cell. 2010;40(2):253–66.

Article  CAS  PubMed  Google Scholar 

Matthews HK, Bertoli C, de Bruin RAM. Cell cycle control in cancer. Nat Rev Mol Cell Biol. 2022;23(1):74–88.

Article  CAS  PubMed  Google Scholar 

Massey A, Stewart J, Smith C, Parvini C, McCormick M, Do K, et al. Mechanical properties of human tumour tissues and their implications for cancer development. Nat Rev Phys. 2024;6(4):269–82.

Article  PubMed  PubMed Central  Google Scholar 

Xin Y, Li K, Huang M, Liang C, Siemann D, Wu L, et al. Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine. Oncogene. 2023;42(47):3457–90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100(1):57–70.

Article  CAS  PubMed  Google Scholar 

Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–74.

Article  CAS  PubMed  Google Scholar 

Hanahan D. Hallmarks of cancer: new dimensions. Cancer Discov. 2022;12(1):31–46.

Article  CAS  PubMed  Google Scholar 

Calderwood SK, Gong J. Heat shock proteins promote cancer: it’s a protection racket. Trends Biochem Sci. 2016;41(4):311–23.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu J, Liu T, Rios Z, Mei Q, Lin X, Cao S. Heat shock proteins and cancer. Trends Pharmacol Sci. 2017;38(3):226–56.

Article  CAS  PubMed  Google Scholar 

Calderwood SK, Khaleque MA, Sawyer DB, Ciocca DR. Heat shock proteins in cancer: chaperones of tumorigenesis. Trends Biochem Sci. 2006;31(3):164–72.

Article  CAS  PubMed  Google Scholar 

Lianos GD, Alexiou GA, Mangano A, Mangano A, Rausei S, Boni L, et al. The role of heat shock proteins in cancer. Cancer Lett. 2015;360(2):114–8.

Article  CAS  PubMed  Google Scholar 

Shevtsov M, Balogi Z, Khachatryan W, Gao H, Vígh L, Multhoff G. Membrane-associated heat shock proteins in oncology: from basic research to new theranostic targets. Cells. 2020;9(5):1263.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang S, Xiao H, Cao L. Recent advances in heat shock proteins in cancer diagnosis, prognosis, metabolism and treatment. Biomed Pharmacother. 2021;142: 112074.

Article  CAS  PubMed  Google Scholar 

Kurop MK, Huyen CM, Kelly JH, Blagg BSJ. The heat shock response and small molecule regulators. Eur J Med Chem. 2021;226: 113846.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yun CW, Kim HJ, Lim JH, Lee SH. Heat shock proteins: agents of cancer development and therapeutic targets in anti-cancer therapy. Cells. 2020;9(1):60.

Article  CAS  Google Scholar 

Chatterjee S, Burns TF. Targeting heat shock proteins in cancer: a promising therapeutic approach. Int J Mol Sci. 2017;18(9):1978.

Article  PubMed  PubMed Central  Google Scholar 

Kampinga HH, Hageman J, Vos MJ, Kubota H, Tanguay RM, Bruford EA, et al. Guidelines for the nomenclature of the human heat shock proteins. Cell Stress Chaperones. 2009;14(1):105–11.

Article