Cytosporones Y and Z, new antifungal polyketides produced by the fungal strain Trichoderma sp. FKI-6626

Cadena J, Thompson GR 3rd, Patterson TF. Aspergillosis: epidemiology, diagnosis, and treatment. Infect Dis Clin North Am. 2021;35:415–34.

Article  PubMed  Google Scholar 

Fernandez-Pittol M, Alejo-Cancho I, Rubio-García E, Cardozo C, Puerta-Alcalde P, Moreno-García E, et al. Aspergillosis by cryptic Aspergillus species: a case series and review of the literature. Rev Iberoam Micol. 2022;39:44–9.

Article  PubMed  Google Scholar 

Alastruey-Izquierdo A, Alcazar-Fuoli L, Cuenca-Estrella M. Antifungal susceptibility profile of cryptic species of Aspergillus. Mycopathologia. 2014;178:427–33.

Article  CAS  PubMed  Google Scholar 

Watanabe Y, Yoshida Y, Tokiwa T, Higo M, Ban S, Ikeda A, et al. Hakuhybotric acid, a new antifungal polyketide produced by a mycoparasitic fungus Hypomyces pseudocorticiicola FKI-9008. J Gen Appl Microbiol. 2022;68:200–6.

Article  CAS  PubMed  Google Scholar 

Watanabe Y, Takahashi S, Ito S, Tokiwa T, Noguchi Y, Azami H, et al. Hakuhybotrol, a polyketide produced by Hypomyces pseudocorticiicola, characterized with the assistance of 3D ED/MicroED. Org Biomol Chem. 2023;21:2320–30.

Article  CAS  PubMed  Google Scholar 

Watanabe Y, Suga T, Narusawa S, Iwatsuki M, Nonaka K, Nakashima T, et al. Decatamariic acid, a new mitochondrial respiration inhibitor discovered by pesticidal screening using drug-sensitive Saccharomyces cerevisiae. J Antibiot. 2017;70:395–9.

Article  CAS  Google Scholar 

Azami H, Watanabe Y, Sakai K, Nakahara H, Kojima H, Tokiwa T, et al. Antifungal profile against Candida auris clinical isolates of tyroscherin and its new analog produced by the deep-sea-derived fungal strain Scedosporium apiospermum FKJ-0499. J Antibiot. 2024;77:156–62.

Ishii T, Nonaka K, Suga T, Masuma R, Ōmura S, Shiomi K. Cytosporone S with antimicrobial activity, isolated from the fungus Trichoderma sp. FKI-6626. Bioorg Med Chem Lett. 2013;23:679–81.

Article  CAS  PubMed  Google Scholar 

Alexander BD, Procop GW, Dufresne P, Espinel-Ingroff A, Fuller J, Ghannoum MA, et al. Reference method for broth dilution antifungal susceptibility testing of filamentous fungi, M38. 3rd ed., Wayne, PA: Clinical and Laboratory Standards Institute; 2017.

Yin Y, Yang W, Chen T, Tan Q, Zou G, Zang Z, et al. Cytosporones W and X: two mutually converting epimers from a mangrove endophytic fungus Diaporthe sp. ZJHJYZ-1. ACS Omega. 2023;8:26628–34.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Beau J, Mahid N, Burda WN, Harrington L, Shaw LN, Mutka T, et al. Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persoonia. Mar Drugs. 2012;10:762–74.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fujimoto K, Yasui M, Tsujimoto T, Ishizaki T, Sudou Y, Uchida Y, et al. Preparation of isochromene derivatives and related compounds for inhibiting RSK1 and AKT. WO2016159021.

Egarnes B, Blanchet MR, Gosselin J. Treatment with the NR4A1 agonist cytosporone B controls influenza virus infection and improves pulmonary function in infected mice. PLoS ONE. 2017;12:e0186639.

Article  PubMed  PubMed Central  Google Scholar 

Brady SF, Wagenaar MM, Singh MP, Janso JE, Clardy J. The cytosporones, new octaketide antibiotics isolated from an endophytic fungus. Org Lett. 2000;2:4043–6.

Article  CAS  PubMed  Google Scholar 

Yin C, Liu H, Shan Y, Gupta VK, Jiang Y, Zhang W, et al. Cytosporone B as a biological preservative: purification, fungicidal activity and mechanism of action against Geotrichum citri-aurantii. Biomolecules. 2019;9:125.

Article  PubMed  PubMed Central  Google Scholar 

Zhan Y, Du X, Chen H, Liu J, Zhao B, Huang D, Li G, et al. Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat Chem Biol. 2008;4:548–56.

Article  CAS  PubMed  Google Scholar 

Hammerschmidt L, Debbab A, Ngoc TD, Wray V, Hemphil CP, Lin W, et al. Polyketides from the mangrove-derived endophytic fungus Acremonium strictum. Tetrahedron Lett. 2014;55:3463–8.

Article  CAS  Google Scholar 

Li L, Zhong W, Liu H, Espinosa-Artiles P, Xu Y, Wang C, et al. Biosynthesis of cytosporones in leotiomycetous filamentous fungi. J Am Chem Sci. 2024;146:6189–98.

Article  CAS  Google Scholar 

留言 (0)

沒有登入
gif