This study was supported by the National Natural Science Foundation of China (grant no. 82272132), the Guangdong Basic and Applied Basic Research Foundation (grant no. 2023A1515110602 and 2024A1515012051), the Regional Joint Fund of Guangdong (Guangdong-Hong Kong-Macao Research Team Project) (grant no. 2021B1515130003), the Key Research and Development Plan Project of Guangzhou (grant no. 2023B03J1246), and the China Postdoctoral Science Foundation (grant no. 2022M721514 and 2024T170386).