Metformin protects against small intestine damage induced by diabetes and dunning’s prostate cancer: A biochemical and histological study

Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121–126. https://doi.org/10.1016/S0076-6879(84)05016-3

Article  CAS  PubMed  Google Scholar 

Ahmed N, Tarannum S (2009) Acetylcholinesterase activity in the brain of alloxan diabetic albino rats: Presence of an inhibitor of this enzyme activity in the cerebral extract. Int J Diabetes Dev Ctries 29:174. https://doi.org/10.4103/0973-3930.57350

Article  PubMed  PubMed Central  Google Scholar 

Ahmed Mobasher M, Galal El-Tantawi H, Samy El-Said K (2020) Metformin ameliorates oxidative stress induced by diabetes mellitus and hepatocellular carcinoma in rats. Rep Biochem Mol Biol 9:115–128. https://doi.org/10.29252/rbmb.9.1.115

Article  PubMed  PubMed Central  Google Scholar 

Al-Faqeeh LAS, Naser R, SR K, Khan SW, Al-Qadsy I, Haidyrah AS, Al-Owais AA, Christy M, Saeed WS (2023) In vitro exploration of Hypsizygus Ulmarius (Bull.) Mushroom fruiting bodies: potential antidiabetic and anti-inflammatory agent. Open Chem J 21(1). https://doi.org/10.1515/chem-2023-0154

Aydın PK, Turkyılmaz IB, Gul IB, Bulan OK, Yanardag R (2023) Drug repurposing: Metformin’s effect against liver tissue damage in diabetes and prostate cancer model. J Diabetes Metab Dis 22:225–236. https://doi.org/10.1007/s40200-022-01109-w

Article  CAS  Google Scholar 

Balamash KS, Alkreathy HM, Al Gahdali EH, Khoja SO, Ahmad A (2018) Comparative biochemical and histopathological studies on the efficacy of metformin and virgin olive oil against Streptozotocin-induced diabetes in Sprague-Dawley rats. J Diabetes Res 2018:4692197. https://doi.org/10.1155/2018/4692197

Bayrak B, Koroglu P, Karabulut Bulan O, Yanardag R (2021) Metformin protects against diabetes-induced heart injury and dunning prostate cancer model. Hum Exp Toxicol 40:297–309. https://doi.org/10.1177/0960327120947452

Article  CAS  PubMed  Google Scholar 

Beutler E (1971) Red cell metabolism. A Manuel of Biochemical Methods. In Academic Press. (12th ed.)

Beutler E (1975) Reduced Glutathione (GSH). In In: Bergmeyen, H.V., Ed., Red Blood Cell Metabolism: A Manual of Biochemical Methods, 2nd Edition, Grune and Stratton, New York (pp. 112–114)

Bravard A, Gérard C, Defois C, Benoit B, Makki K, Meugnier E, Rainteau D, Rieusset J, Godet M, Vidal H (2021) Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice. Sci Rep 11:16684. https://doi.org/10.1038/s41598-021-95117-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bugan I, Karagoz Z, Altun S, Djamgoz MBA (2016) Gabapentin, an analgesic used against cancer-associated neuropathic pain: effects on prostate cancer progression in an in vivo rat model. Basic Clin Pharmacol Toxicol 118:200–207. https://doi.org/10.1111/bcpt.12484

Article  CAS  PubMed  Google Scholar 

Çakına S, Öztürk Ş (2020) Oxidative stress markers in liver in streptozocin-induced diabetic rats: effects of metformin and sitagliptin. Cukurova Med J 45:1733–1741. https://doi.org/10.17826/cumj.791369

Article  Google Scholar 

Caspary WF, Rhein AM, Creutzfeldt W (1972) Increase of intestinal brush border hydrolases in mucosa of streptozotocin-diabetic rats. Diabetologia 8:412–414. https://doi.org/10.1007/BF01212169

Article  CAS  PubMed  Google Scholar 

Corte ED, Stirpe F (1968) Regulation of xanthine oxidase in rat liver: modifications of the enzyme activity of rat liver supernatant on storage at 20 degrees. Biochem J 108:349–351. https://doi.org/10.1042/bj1080349

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dahlqvist A (1968) Assay of intestinal disaccharidases. Anal Biochem 22:99–107. https://doi.org/10.1016/0003-2697(68)90263-7

Article  CAS  PubMed  Google Scholar 

Del Rio D, Stewart AJ, Pellegrini N (2005) A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress. Nutr Metab Cardiovasc Dis 15:316–328. https://doi.org/10.1016/j.numecd.2005.05.003

Article  PubMed  Google Scholar 

Deng J, Zeng L, Lai X, Li J, Liu L, Lin Q, Chen Y (2018) Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation. J Cell Mol Med 22:546–557. https://doi.org/10.1111/jcmm.13342

Article  CAS  PubMed  Google Scholar 

Duan R-D, Poensgen J, Wicker C, Weström B, Erlanson-Albertsson C (1989) Increase in pancreatic lipase and trypsin activity and their mRNA levels in streptozotocin-induced diabetic rats. Dig Dis Sci 34:1243–1248. https://doi.org/10.1007/BF01537273

Article  CAS  PubMed  Google Scholar 

Ellman GL, Courtney KD, Andres V, Featherstone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88–95. https://doi.org/10.1016/0006-2952(61)90145-9

Article  CAS  PubMed  Google Scholar 

Erel O (2004) A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem 37:277–285. https://doi.org/10.1016/j.clinbiochem.2003.11.015

Article  CAS  PubMed  Google Scholar 

Erel O (2005) A new automated colorimetric method for measuring total oxidant status. Clin Biochem 38:1103–1111. https://doi.org/10.1016/j.clinbiochem.2005.08.008

Article  CAS  PubMed  Google Scholar 

Farag A, Mandour AS, Hendawy H, Elhaieg A, Elfadadny A, Tanaka R (2023) A review on experimental surgical models and anesthetic protocols of heart failure in rats. Front Vet Sci 10:1103229. https://doi.org/10.3389/fvets.2023.1103229

Article  PubMed  PubMed Central  Google Scholar 

Felippe Gonçalves-de-Albuquerque C, Ribeiro Silva A, Ignácio da Silva C, Caire Castro-Faria-Neto H, Burth P (2017) Na/K pump and beyond: Na/K-ATPase as a modulator of apoptosis and autophagy. Molecules 22(4):578. https://doi.org/10.3390/molecules22040578

Article  CAS  PubMed  PubMed Central  Google Scholar 

Figueiredo ID, Lima TFO, Inácio MD, Costa MC, Assis RP, Brunetti IL, Baviera AM (2020) Lycopene improves the metformin effects on glycemic control and decreases biomarkers of glycoxidative stress in diabetic rats. Diabetes Metab Syndr Obes Targets Ther 13:3117–3135. https://doi.org/10.2147/DMSO.S265944

Article  CAS  Google Scholar 

Foretz M, Guigas B, Viollet B (2023) Metformin: update on mechanisms of action and repurposing potential. Nat Rev Endocrinol 19:460–476. https://doi.org/10.1038/s41574-023-00833-4

Article  CAS  PubMed  Google Scholar 

Freitas-Júnior ACV, Costa HMS, Icimoto MY, Hirata IY, Marcondes M, Carvalho LB, Oliveira V, Bezerra RS (2012) Giant amazonian fish pirarucu (Arapaima gigas): its viscera as a source of thermostable trypsin. Food Chem 133:1596–1602. https://doi.org/10.1016/j.foodchem.2012.02.056

Article  CAS  Google Scholar 

Fukai T, Ushio-Fukai M (2011) Superoxide dismutases: role in redox signaling, vascular function, and diseases. Antioxid Redox Signal 15:1583–1606. https://doi.org/10.1089/ars.2011.3999

Article  CAS  PubMed  PubMed Central  Google Scholar 

Funk CD (2001) Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 294:1871–1875. https://doi.org/10.1126/science.294.5548.1871

Article  CAS  PubMed  Google Scholar 

Furlong CE, Richter RJ, Seidel SL, Motulsky AG (1988) Role of genetic polymorphism of human plasma paraoxonase/arylesterase in hydrolysis of the insecticide metabolites chlorpyrifos oxon and paraoxon. Am J Hum Genet 43:230–238

CAS  PubMed  PubMed Central  Google Scholar 

Gianazza E, Brioschi M, Fernandez AM, Banfi C (2019) Lipoxidation in cardiovascular diseases. Redox Biol 23:101119. https://doi.org/10.1016/j.redox.2019.101119

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gotfried J, Priest S, Schey R (2017) Diabetes and the small intestine. Curr Treat Options Gastroenterol 15:490–507. https://doi.org/10.1007/s11938-017-0155-x

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif