Wasnich RD (1996) Vertebral fracture epidemiology. Bone. ;18(3 Suppl):179S-183S. https://doi.org/10.1016/8756-3282(95)00499-8. PMID: 8777085

Mazziotti G, Frara S, Giustina A (2018) Pituitary Diseases and Bone. Endocr Rev. ;39(4):440–488. https://doi.org/10.1210/er.2018-00005. PMID: 29684108

Mazziotti G, Bilezikian J, Canalis E, Cocchi D, Giustina A (2012) New understanding and treatments for osteoporosis. Endocrine. ;41(1):58–69. https://doi.org/10.1007/s12020-011-9570-2. PMID: 22180055

Chiloiro S, Capoluongo ED, Tartaglione T, Giampietro A, Bianchi A, Giustina A, Pontecorvi A, De Marinis L (2019) The changing clinical spectrum of Hypophysitis. Trends Endocrinol Metab 30(9):590–602. https://doi.org/10.1016/j.tem.2019.06.004Epub 2019 Jul 22. PMID: 31345630

Article  CAS  PubMed  Google Scholar 

Costanza F, Giampietro A, Mattogno PP, Chiloiro S (2023) Colon cancer presenting as Pituitary Mass and Hypopituitarism: Recognition and Multidisciplinary Approach of a rare case. JCEM Case Rep 1(2):luad031. https://doi.org/10.1210/jcemcr/luad031PMID: 37908471; PMCID: PMC10580474

Article  PubMed  PubMed Central  Google Scholar 

Calandrelli R, Pilato F, Massimi L, D’Apolito G, Grimaldi A, Chiloiro S, Bianchi A, Gessi M, Gaudino S (2024) Pediatric craniopharyngiomas: magnetic resonance imaging assessment for hypothalamus-pituitary axis dysfunction and outcome prediction. Pediatr Radiol 54(1):157–169 Epub 2023 Nov 29. PMID: 38019284

Article  PubMed  Google Scholar 

Yavropoulou MP, Tsoli M, Kaltsas G (2021) Neuroendocrine manifestations of Langerhans cell histiocytosis. Handb Clin Neurol. ;181:127–135. https://doi.org/10.1016/B978-0-12-820683-6.00009-9. PMID: 34238452

Celik O, Ozyurt S, Saglican Y (2020) Suprasellar germinoma with hypopituitarism in an 18-year old man: a case report and review of literature. Clin Neurol Neurosurg 196:106026. https://doi.org/10.1016/j.clineuro.2020.106026Epub 2020 Jun 15. PMID: 32580069

Article  PubMed  Google Scholar 

Chiloiro S, Giampietro A, Bianchi A, De Marinis L (2016) Clinical management of teratoma, a rare hypothalamic-pituitary neoplasia. Endocrine 53(3):636–642. https://doi.org/10.1007/s12020-015-0814-4Epub 2015 Dec 23. PMID: 26701679

Article  CAS  PubMed  Google Scholar 

Pivonello R, Isidori AM, De Martino MC et al (2016) Complications of Cushing’s syndrome: state of the art. Lancet Diabetes Endocrinol 4:611–629 1016/S2213- 8587(16)00086 – 3

Article  CAS  PubMed  Google Scholar 

van der Eerden AW, den Heijer M, Oyen WJ, Hermus AR (2007) Cushing’s syndrome and bone mineral density: lowest Z scores in young patients. Neth J Med 65(4):137–141 PMID: 17452762

PubMed  Google Scholar 

Apaydın T, Yavuz DG (2021) Assessment of non-traumatic vertebral fractures in Cushing’s syndrome patients. J Endocrinol Invest 44(8):1767–1773. https://doi.org/10.1007/s40618-020-01496-yEpub 2021 Jan 9. PMID: 33420960

Article  CAS  PubMed  Google Scholar 

Biller BM, Baum HB, Rosenthal DI, Saxe VC, Charpie PM, Klibanski A (1992) Progressive trabecular osteopenia in women with hyperprolactinemic amenorrhea. J Clin Endocrinol Metab. ;75(3):692-7. https://doi.org/10.1210/jcem.75.3.1517356. PMID: 1517356

Cann CE, Martin MC, Genant HK, Jaffe RB (1984) Decreased spinal mineral content in amenorrheic women. JAMA. ;251(5):626-9. PMID: 6690836

Mazziotti G, Porcelli T, Mormando M, De Menis E, Bianchi A, Mejia C, Mancini T, De Marinis L, Giustina A (2011) Vertebral fractures in males with prolactinoma. Endocrine 39(3):288–293. https://doi.org/10.1007/s12020-011-9462-5Epub 2011 Apr 10. PMID: 21479837

Article  CAS  PubMed  Google Scholar 

Dutta D, Dharmshaktu P, Aggarwal A, Gaurav K, Bansal R, Devru N, Garga UC, Kulshreshtha B (2016 Jul-Sep) Severity and pattern of bone mineral loss in endocrine causes of osteoporosis as compared to age-related bone mineral loss. J Postgrad Med 62(3):162–169. https://doi.org/10.4103/0022-3859.183170PMID: 27241810; PMCID: PMC4970342

Scillitani A, Mazziotti G, Di Somma C, Moretti S, Stigliano A, Pivonello R, Giustina A, Colao A, ABC Group (2014) Treatment of skeletal impairment in patients with endogenous hypercortisolism: when and how? Osteoporos Int 25(2):441–446. https://doi.org/10.1007/s00198-013-2588-yEpub 2013 Dec 6. PMID: 24311114

Article  CAS  PubMed  Google Scholar 

Frara S, di Filippo L, Doga M, Loli P, Casanueva FF, Giustina A (2022) Novel approaches to bone comorbidity in Cushing’s disease: an update. Pituitary 25(5):754–759. https://doi.org/10.1007/s11102-022-01252-wEpub 2022 Jul 18. PMID: 35849272

Article  PubMed  Google Scholar 

Kaplan FS, Leone VJ, Fallon MD, Haddad JG, Brighton CT, Steinberg ME (1987) Multiple pathologic fractures of the appendicular skeleton in a patient with Cushing’s disease. Clin Orthop Relat Res. ;(216):171–175. PMID: 3815944.

Mazziotti G, Bianchi A, Porcelli T, Mormando M, Maffezzoni F, Cristiano A, Giampietro A, De Marinis L, Giustina A (2013) Vertebral fractures in patients with acromegaly: a 3-year prospective study. J Clin Endocrinol Metab 98(8):3402–3410. https://doi.org/10.1210/jc.2013-1460Epub 2013 Jun 14. PMID: 23771918

Article  CAS  PubMed  Google Scholar 

Frara S, Melin Uygur M, di Filippo L, Doga M, Losa M, Santoro S, Mortini P, Giustina A (2022) High Prevalence of Vertebral Fractures Associated With Preoperative GH Levels in Patients With Recent Diagnosis of Acromegaly. J Clin Endocrinol Metab. ;107(7):e2843-e2850. https://doi.org/10.1210/clinem/dgac183. PMID: 35349698

Madeira M, Neto LV, de Paula Paranhos Neto F, Barbosa Lima IC, Carvalho de Mendonça LM, Gadelha MR, Fleiuss de Farias ML (2013) Acromegaly has a negative influence on trabecular bone, but not on cortical bone, as assessed by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab 98(4):1734–1741. https://doi.org/10.1210/jc.2012-4073Epub 2013 Mar 12. PMID: 23482608

Article  CAS  PubMed  Google Scholar 

Battista C, Chiodini I, Muscarella S, Guglielmi G, Mascia ML, Carnevale V, Scillitani A (2009) Spinal volumetric trabecular bone mass in acromegalic patients: a longitudinal study. Clin Endocrinol (Oxf) 70(3):378–382. https://doi.org/10.1111/j.1365-2265.2008.03322.xEpub 2008 Jun 23. PMID: 18616713

Article  PubMed  Google Scholar 

Kužma M, Vaňuga P, Ságová I, Pávai D, Jackuliak P, Killinger Z, Binkley N, Winzenrieth R, Payer J (2021) Vertebral Fractures Occur Despite Control of Acromegaly and Are Predicted by Cortical Volumetric Bone Mineral Density. J Clin Endocrinol Metab. ;106(12):e5088-e5096. https://doi.org/10.1210/clinem/dgab259. PMID: 34270719

Mazziotti G, Doga M, Frara S, Maffezzoni F, Porcelli T, Cerri L, Maroldi R, Giustina A (2016) Incidence of morphometric vertebral fractures in adult patients with growth hormone deficiency. Endocrine. ;52(1):103 – 10. https://doi.org/10.1007/s12020-015-0738-z. Epub 2015 Oct 3. PMID: 26433736

Giustina A, Lazaretti-Castro M, Martineau AR, Mason RS, Rosen CJ, Schoenmakers I (2024) A view on vitamin D: a pleiotropic factor? Nat Rev Endocrinol. ;20(4):202–208. https://doi.org/10.1038/s41574-023-00942-0. PMID: 38253860

Medrano M, Carrillo-Cruz E, Montero I, Perez-Simon JA, Vitamin D (2018) Effect on Haematopoiesis and Immune System and clinical applications. Int J Mol Sci 19(9):2663. https://doi.org/10.3390/ijms19092663PMID: 30205552; PMCID: PMC6164750

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park JE, Pichiah PBT, Cha YS (2018) Vitamin D and metabolic diseases: growing roles of vitamin D. J Obes Metab Syndr 27(4):223–232. https://doi.org/10.7570/jomes.2018.27.4.223Epub 2018 Dec 30. PMID: 31089567; PMCID: PMC6513299

Article  PubMed  PubMed Central  Google Scholar 

Giustina A, Bilezikian JP, Adler RA, Banfi G, Bikle DD, Binkley NC, Bollerslev J, Bouillon R, Brandi ML, Casanueva FF, di Filippo L, Donini LM, Ebeling PR, Fuleihan GE, Fassio A, Frara S, Jones G, Marcocci C, Martineau AR, Minisola S, Napoli N, Procopio M, Rizzoli R, Schafer AL, Sempos CT, Ulivieri FM, Virtanen JK Consensus Statement on vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows. Endocr Rev 2024 Apr 27:bnae009. https://doi.org/10.1210/endrev/bnae009. Epub ahead of print. PMID: 38676447.

Reid IR, Bolland MJ (2020) Calcium and/or vitamin D supplementation for the Prevention of Fragility fractures. Who Needs It? Nutrients 12(4):1011. https://doi.org/10.3390/nu12041011PMID: 32272593; PMCID: PMC7231370

Article  CAS  PubMed  Google Scholar 

Giustina A, Adler RA, Binkley N, Bollerslev J, Bouillon R, Dawson-Hughes B, Ebeling PR, Feldman D, Formenti AM, Lazaretti-Castro M, Marcocci C, Rizzoli R, Sempos CT, Bilezikian JP (2020) Consensus statement from 2nd International Conference on Controversies in Vitamin D. Rev Endocr Metab Disord. ;21(1):89–116. https://doi.org/10.1007/s11154-019-09532-w. PMID: 32180081; PMCID: PMC7113202

Giustina A, Bouillon R, Dawson-Hughes B, Ebeling PR, Lazaretti-Castro M, Lips P, Marcocci C, Bilezikian JP (2023) Vitamin D in the older population: a consensus statement. Endocrine. ;79(1):31–44. https://doi.org/10.1007/s12020-022-03208-3. PMID: 36287374

Giustina A, Bouillon R, Binkley N, Sempos C, Adler RA, Bollerslev J, Dawson-Hughes B, Ebeling PR, Feldman D, Heijboer A, Jones G, Kovacs CS, Lazaretti-Castro M, Lips P, Marcocci C, Minisola S, Napoli N, Rizzoli R, Scragg R, White JH, Formenti AM, Bilezikian JP (2020) Controversies in Vitamin D: A Statement From the Third International Conference. JBMR Plus. ;4(12):e10417. https://doi.org/10.1002/jbm4.10417. PMID: 33354643; PMCID: PMC7745884

Bouillon R (2017) Comparative analysis of nutritional guidelines for vitamin D. Nat Rev Endocrinol. ;13(8):466–479. https://doi.org/10.1038/nrendo.2017.31. Epub 2017 Apr 7. PMID: 28387318

Lips P, van Schoor NM (2011) The effect of vitamin D on bone and osteoporosis. Best Pract Res Clin Endocrinol Metab. ;25(4):585 – 91. https://doi.org/10.1016/j.beem.2011.05.002. PMID: 21872800

Cangussu LM, Nahas-Neto J, Orsatti CL, Bueloni-Dias FN, Nahas EA (2015) Effect of vitamin D supplementation alone on muscle function in postmenopausal women: a randomized, double-blind, placebo-controlled clinical trial. Osteoporos Int 26(10):2413–2421. https://doi.org/10.1007/s00198-015-3151-9Epub 2015 May 9. PMID: 25956283

Article  CAS  PubMed  Google Scholar 

Bischoff-Ferrari HA, Willett WC, Orav EJ, Lips P, Meunier PJ, Lyons RA, Flicker L, Wark J, Jackson RD, Cauley JA, Meyer HE, Pfeifer M, Sanders KM, Stähelin HB, Theiler R, Dawson-Hughes B (2012) A pooled analysis of vitamin D dose requirements for fracture prevention. N Engl J Med. ;367(1):40 – 9. doi: 10.1056/NEJMoa1109617. Erratum in: N Engl J Med. 2012;367(5):481. Oray, Endel J [corrected to Orav, Endel J]. PMID: 22762317

Trivedi DP, Doll R, Khaw KT (2003) Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ 326(7387):469. https://doi.org/10.1136/bmj.326.7387.469PMID: 12609940; PMCID: PMC150177

Article  CAS  PubMed  PubMed Central  Google Scholar 

LeBoff MS, Chou SH, Murata EM, Donlon CM, Cook NR, Mora S, Lee IM, Kotler G, Bubes V, Buring JE, Manson JE (2020) Effects of Supplemental Vitamin D on Bone Health outcomes in Women and men in the VITamin D and OmegA-3 TriaL (VITAL). J Bone Min Res 35(5):883–893 Epub 2020 Jan 30. PMID: 31923341; PMCID: PMC7217747

Article  CAS  Google Scholar 

Rossini M, Adami S, Bertoldo F, Diacinti D, Gatti D, Giannini S, Giusti A, Malavolta N, Minisola S, Osella G, Pedrazzoni M, Sinigaglia L, Viapiana O, Isaia GC (2016) Guidelines for the diagnosis, prevention and management of osteoporosis. Reumatismo. ;68(1):1–39. https://doi.org/10.4081/reumatismo.2016.870. PMID: 27339372

Giustina A (2023) Acromegaly and bone: an update. Endocrinol Metab (Seoul) 38(6):655–666. https://doi.org/10.3803/EnM.2023.601Epub 2023 Dec 22. PMID: 38164073; PMCID: PMC10764988

Article  CAS  PubMed  Google Scholar 

Shah R, Licata A, Oyesiku NM, Ioachimescu AG (2012) Acromegaly as a cause of 1,25-dihydroxyvitamin D-dependent hypercalcemia: case reports and review of the literature. Pituitary. ;15 Suppl 1:S17-22. https://doi.org/10.1007/s11102-010-0286-8. PMID: 21188640

Lund B, Eskildsen PC, Lund B, Norman AW, Sørensen OH (1981) Calcium and vitamin D metabolism in acromegaly. Acta Endocrinol (Copenh). ;96(4):444 – 50. https://doi.org/10.1530/acta.0.0960444. PMID: 7211102

Spencer EM, Tobiassen O (1981) The mechanism of the action of growth hormone on vitamin D metabolism in the rat. Endocrinology. ;108(3):1064-70. https://doi.org/10.1210/endo-108-3-1064. PMID: 7460832

Eskildsen PC, Lund B, Sørensen OH, Lund B, Bishop JE, Norman AW (1979) Acromegaly and vitamin D metabolism: effect of bromocriptine treatment. J Clin Endocrinol Metab. ;49(3):484-6. https://doi.org/10.1210/jcem-49-3-484. PMID: 468984