Kinane DF, Stathopoulou PG, Papapanou PN. Periodontal diseases. Nat Rev Dis Primers [Internet]. 2017;3:17038. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28805207
Janakiram C, Dye BA. A public health approach for prevention of periodontal disease. Periodontol 2000 [Internet]. 2020;84:202–14. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32844412
Canada. Health Canada. Summary report on the findings of the oral health component of the Canadian health measures survey, 2007–2009. Health Canada; 2010. Available from: https://publications.gc.ca/site/eng/9.693377/publication.htm
Eke PI, Borgnakke WS, Genco RJ. Recent epidemiologic trends in periodontitis in the USA. Periodontol 2000 [Internet]. 2020;82:257–67. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31850640
DeSantis CE, Miller KD, Dale W, Mohile SG, Cohen HJ, Leach CR, et al. Cancer statistics for adults aged 85 years and older, 2019. CA Cancer J Clin [Internet]. 2019;69:452–67. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31390062
Hajishengallis G, Chavakis T. Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities. Nat Rev Immunol [Internet]. 2021;21:426–40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/33510490
Fan Z, Tang P, Li C, Yang Q, Xu Y, Su C, et al. Fusobacterium nucleatum and its associated systemic diseases: epidemiologic studies and possible mechanisms. J Oral Microbiol [Internet]. 2023;15:2145729. Available from: http://www.ncbi.nlm.nih.gov/pubmed/36407281
Alon-Maimon T, Mandelboim O, Bachrach G. Fusobacterium nucleatum and cancer. Periodontol 2000 [Internet]. 2022;89:166–80. Available from: http://www.ncbi.nlm.nih.gov/pubmed/35244982
Bolstad AI, Jensen HB, Bakken V. Taxonomy, biology, and periodontal aspects of Fusobacterium nucleatum. Clin Microbiol Rev [Internet]. 1996;9:55–71. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8665477
Chagnot C, Zorgani MA, Astruc T, Desvaux M. Proteinaceous determinants of surface colonization in bacteria: bacterial adhesion and biofilm formation from a protein secretion perspective. Front Microbiol [Internet]. 2013;4:303. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24133488
Rubinstein MR, Wang X, Liu W, Hao Y, Cai G, Han YW. Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin. Cell Host Microbe [Internet]. 2013;14:195–206. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23954158
Feller L, Blignaut E. Halitosis: a review. SADJ [Internet]. 2005;60:17–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15861957
Hajishengallis G, Liang S, Payne MA, Hashim A, Jotwani R, Eskan MA, et al. Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host Microbe [Internet]. 2011;10:497–506. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22036469
Tanner ACR, Paster BJ, Lu SC, Kanasi E, Kent R, Van Dyke T, et al. Subgingival and tongue microbiota during early periodontitis. J Dent Res [Internet]. 2006;85:318–23. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16567551
Kolenbrander PE, Palmer RJ, Periasamy S, Jakubovics NS. Oral multispecies biofilm development and the key role of cell-cell distance. Nat Rev Microbiol [Internet]. 2010;8:471–80. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20514044
Uitto V-J, Baillie D, Wu Q, Gendron R, Grenier D, Putnins EE, et al. Fusobacterium nucleatum increases collagenase 3 production and migration of epithelial cells. Infect Immun [Internet]. 2005;73:1171–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15664960
Greer A, Zenobia C, Darveau RP. Defensins and LL-37: a review of function in the gingival epithelium. Periodontol 2000 [Internet]. 2013;63:67–79. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23931055
Al-Hebshi NN, Nasher AT, Maryoud MY, Homeida HE, Chen T, Idris AM, et al. Inflammatory bacteriome featuring Fusobacterium nucleatum and Pseudomonas aeruginosa identified in association with oral squamous cell carcinoma. Sci Rep [Internet]. 2017;7:1834. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28500338
Nagy KN, Sonkodi I, Szöke I, Nagy E, Newman HN. The microflora associated with human oral carcinomas. Oral Oncol [Internet]. 1998;34:304–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9813727
Zhang L, Liu Y, Zheng HJ, Zhang CP. The Oral Microbiota May Have Influence on Oral Cancer. Front Cell Infect Microbiol [Internet]. 2019;9:476. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32010645
Bronzato JD, Bomfim RA, Edwards DH, Crouch D, Hector MP, Gomes BPFA. Detection of Fusobacterium in oral and head and neck cancer samples: A systematic review and meta-analysis. Arch Oral Biol [Internet]. 2020;112:104669. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32028171
Shin JM, Luo T, Kamarajan P, Fenno JC, Rickard AH, Kapila YL. Microbial Communities Associated with Primary and Metastatic Head and Neck Squamous Cell Carcinoma - A High Fusobacterial and Low Streptococcal Signature. Sci Rep [Internet]. 2017;7:9934. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28855542
Chen Z, Wong PY, Ng CWK, Lan L, Fung S, Li JW, et al. The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell Carcinoma. Cancers (Basel) [Internet]. 2020;12:1–20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/33218162
Neuzillet C, Marchais M, Vacher S, Hilmi M, Schnitzler A, Meseure D, et al. Prognostic value of intratumoral Fusobacterium nucleatum and association with immune-related gene expression in oral squamous cell carcinoma patients. Sci Rep [Internet]. 2021;11:7870. Available from: http://www.ncbi.nlm.nih.gov/pubmed/33846399
McIlvanna E, Linden GJ, Craig SG, Lundy FT, James JA. Fusobacterium nucleatum and oral cancer: a critical review. BMC Cancer [Internet]. 2021;21:1212. Available from: http://www.ncbi.nlm.nih.gov/pubmed/34774023
Kelley N, Jeltema D, Duan Y, He Y. The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation. Int J Mol Sci [Internet]. 2019;20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31284572
Lee C-H, Chang JS-M, Syu S-H, Wong T-S, Chan JY-W, Tang Y-C, et al. IL-1β promotes malignant transformation and tumor aggressiveness in oral cancer. J Cell Physiol [Internet]. 2015;230:875–84. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25204733
Yao Y, Shen X, Zhou M, Tang B. Periodontal Pathogens Promote Oral Squamous Cell Carcinoma by Regulating ATR and NLRP3 Inflammasome. Front Oncol [Internet]. 2021;11:722797. Available from: http://www.ncbi.nlm.nih.gov/pubmed/34660289
O’Shea JJ, Schwartz DM, Villarino A V, Gadina M, McInnes IB, Laurence A. The JAK-STAT pathway: impact on human disease and therapeutic intervention. Annu Rev Med [Internet]. 2015;66:311–28. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25587654
Geng F, Zhang Y, Lu Z, Zhang S, Pan Y. Fusobacterium nucleatum Caused DNA Damage and Promoted Cell Proliferation by the Ku70/p53 Pathway in Oral Cancer Cells. DNA Cell Biol [Internet]. 2020;39:144–51. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31765243
Siegel RL, Miller KD, Fedewa SA, Ahnen DJ, Meester RGS, Barzi A, et al. Colorectal cancer statistics, 2017. CA Cancer J Clin [Internet]. 2017;67:177–93. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28248415
Kostic AD, Gevers D, Pedamallu CS, Michaud M, Duke F, Earl AM, et al. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res [Internet]. 2012;22:292–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22009990
Gethings-Behncke C, Coleman HG, Jordao HWT, Longley DB, Crawford N, Murray LJ, et al. Fusobacterium nucleatum in the Colorectum and Its Association with Cancer Risk and Survival: A Systematic Review and Meta-analysis. Cancer Epidemiol Biomarkers Prev [Internet]. 2020;29:539–48. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31915144
Koliarakis I, Messaritakis I, Nikolouzakis TK, Hamilos G, Souglakos J, Tsiaoussis J. Oral Bacteria and Intestinal Dysbiosis in Colorectal Cancer. Int J Mol Sci [Internet]. 2019;20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/31450675
Castellarin M, Warren RL, Freeman JD, Dreolini L, Krzywinski M, Strauss J, et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Res [Internet]. 2012;22:299–306. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22009989
Lee D-W, Han S-W, Kang J-K, Bae JM, Kim H-P, Won J-K, et al. Association Between Fusobacterium nucleatum, Pathway Mutation, and Patient Prognosis in Colorectal Cancer. Ann Surg Oncol [Internet]. 2018;25:3389–95. Available from: http://www.ncbi.nlm.nih.gov/pubmed/30062471
Komiya Y, Shimomura Y, Higurashi T, Sugi Y, Arimoto J, Umezawa S, et al. Patients with colorectal cancer have identical strains of Fusobacterium nucleatum in their colorectal cancer and oral cavity. Gut [Internet]. 2019;68:1335–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29934439
Abed J, Emgård JEM, Zamir G, Faroja M, Almogy G, Grenov A, et al. Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc. Cell Host Microbe [Internet]. 2016;20:215–25. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27512904
Yang Y, Weng W, Peng J, Hong L, Yang L, Toiyama Y, et al. Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-κB, and Up-regulating Expression of MicroRNA-21. Gastroenterology [Internet]. 2017;152:851–866.e24. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27876571
Wong SH, Kwong TNY, Chow T-C, Luk AKC, Dai RZW, Nakatsu G, et al. Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia. Gut [Internet]. 2017;66:1441–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27797940
Wang H-F, Li L-F, Guo S-H, Zeng Q-Y, Ning F, Liu W-L, et al. Evaluation of antibody level against Fusobacterium nucleatum in the serological diagnosis of colorectal cancer. Sci Rep [Internet]. 2016;6:33440. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27678333
Gobbo M, Joy J, Guedes H, Shazib MA, Anderson C, Abdalla-Aslan R, et al. Emerging pharmacotherapy trends in preventing and managing oral mucositis induced by chemoradiotherapy and targeted agents. Expert Opin Pharmacother [Internet]. 2024;25:727–42. Available from: http://www.ncbi.nlm.nih.gov/pubmed/38808634
Cosseau C, Devine DA, Dullaghan E, Gardy JL, Chikatamarla A, Gellatly S, et al. The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis. Infect Immun [Internet]. 2008;76:4163–75. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18625732
Mehta RS, Nishihara R, Cao Y, Song M, Mima K, Qian ZR, et al. Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue. JAMA Oncol [Internet]. 2017;3:921–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28125762
Yamamura K, Baba Y, Nakagawa S, Mima K, Miyake K, Nakamura K, et al. Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis. Clin Cancer Res [Internet]. 2016;22:5574–81. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27769987
Fan X, Alekseyenko A V, Wu J, Peters BA, Jacobs EJ, Gapstur SM, et al. Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study. Gut [Internet]. 2018;67:120–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27742762
Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, et al. Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis. Oncotarget [Internet]. 2015;6:7209–20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25797243
Yamamura K, Baba Y, Miyake K, Nakamura K, Shigaki H, Mima K, et al. Fusobacterium nucleatum in gastroenterological cancer: Evaluation of measurement methods using quantitative polymerase chain reaction and a literature review. Oncol Lett [Internet]. 2017;14:6373–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29151903
Bullman S, Pedamallu CS, Sicinska E, Clancy TE, Zhang X, Cai D, et al. Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer. Science [Internet]. 2017;358:1443–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29170280
Sugano K, Tack J, Kuipers EJ, Graham DY, El-Omar EM, Miura S, et al. Kyoto global consensus report on Helicobacter pylori gastritis. Gut [Internet]. 2015;64:1353–67. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26187502
Castaño-Rodríguez N, Goh K-L, Fock KM, Mitchell HM, Kaakoush NO. Dysbiosis of the microbiome in gastric carcinogenesis. Sci Rep [Internet]. 2017;7:15957. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29162924
Hsieh Y-Y, Tung S-Y, Pan H-Y, Yen C-W, Xu H-W, Lin Y-J, et al. Increased Abundance of Clostridium and Fusobacterium in Gastric Microbiota of Patients with Gastric Cancer in Taiwan. Sci Rep [Internet]. 2018;8:158. Available from: http://www.ncbi.nlm.nih.gov/pubmed/29317709
Gaba FI, González RC, Martïnez RG. The Role of Oral Fusobacterium nucleatum in Female Breast Cancer: A Systematic Review and Meta-Analysis. Int J Dent [Internet]. 2022;2022:1876275. Available from: http://www.ncbi.nlm.nih.gov/pubmed/36466367
Parhi L, Alon-Maimon T, Sol A, Nejman D, Shhadeh A, Fainsod-Levi T, et al. Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression. Nat Commun [Internet]. 2020;11:3259. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32591509
Pinder SE, Ellis IO. Ductal carcinoma in situ (DCIS) and atypical ductal hyperplasia (ADH) - Current definitions and classification. Breast Cancer Research. 2003. p. 254–7.
Van der Merwe M, Van Niekerk G, Botha A, Engelbrecht A-M. The onco-immunological implications of Fusobacterium nucleatum in breast cancer. Immunol Lett [Internet]. 2021;232:60–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/33647328
Yuan S, Fang C, Leng W-D, Wu L, Li B-H, Wang X-H, et al. Oral microbiota in the oral-genitourinary axis: identifying periodontitis as a potential risk of genitourinary cancers. Mil Med Res [Internet]. 2021;8:54. Available from: http://www.ncbi.nlm.nih.gov/pubmed/34588004
Bučević Popović V, Šitum M, Chow C-ET, Chan LS, Roje B, Terzić J. The urinary microbiome associated with bladder cancer. Sci Rep [Internet]. 2018;8:12157. Available from: http://www.ncbi.nlm.nih.gov/pubmed/30108246
Alluri LSC, Paes Batista da Silva A, Verma S, Fu P, Shen DL, MacLennan G, et al. Presence of Specific Periodontal Pathogens in Prostate Gland Diagnosed With Chronic Inflammation and Adenocarcinoma. Cureus [Internet]. 2021;13:e17742. Available from: http://www.ncbi.nlm.nih.gov/pubmed/34659955
Huang S-T, Chen J, Lian L-Y, Cai H-H, Zeng H-S, Zheng M, et al. Intratumoral levels and prognostic significance of Fusobacterium nucleatum in cervical carcinoma. Aging [Internet]. 2020;12:23337–50. Available from: http://www.ncbi.nlm.nih.gov/pubmed/33197886
Wu N, Feng Y-Q, Lyu N, Wang D, Yu W-D, Hu Y-F. Fusobacterium nucleatum promotes colon cancer progression by changing the mucosal microbiota and colon transcriptome in a mouse model. World J Gastroenterol [Internet]. 2022;28:1981–95. Available from: http://www.ncbi.nlm.nih.gov/pubmed/35664967
Harrandah AM, Chukkapalli SS, Bhattacharyya I, Progulske-Fox A, Chan EKL. Fusobacteria modulate oral carcinogenesis and promote cancer progression. J Oral Microbiol [Internet]. 2020;13:1849493. Available from: http://www.ncbi.nlm.nih.gov/pubmed/33391626
Yu T, Guo F, Yu Y, Sun T, Ma D, Han J, et al. Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy. Cell [Internet]. 2017;170:548–563.e16. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28753429
Tanida I, Minematsu-Ikeguchi N, Ueno T, Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy [Internet]. 2005;1:84–91. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16874052
Perez-Ordoñez B, Beauchemin M, Jordan RCK. Molecular biology of squamous cell carcinoma of the head and neck. J Clin Pathol [Internet]. 2006;59:445–53. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16644882
Ojima T, Nakamori M, Nakamura M, Katsuda M, Hayata K, Kato T, et al. Neoadjuvant Chemotherapy with Divided-dose Docetaxel, Cisplatin and Fluorouracil for Patients with Squamous Cell Carcinoma of the Esophagus. Anticancer Res [Internet]. 2016;36:829–34. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26851048
Gur C, Ibrahim Y, Isaacson B, Yamin R, Abed J, Gamliel M, et al. Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. Immunity [Internet]. 2015;42:344–55. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25680274
Casasanta MA, Yoo CC, Udayasuryan B, Sanders BE, Umaña A, Zhang Y, et al. Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration. Sci Signal [Internet]. 2020;13. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32694172
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer [Internet]. 2002;2:442–54. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12189386
Abdulkareem AA, Shelton RM, Landini G, Cooper PR, Milward MR. Periodontal pathogens promote epithelial-mesenchymal transition in oral squamous carcinoma cells in vitro. Cell Adh Migr [Internet]. 2018;12:127–37. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28873015
Baud J, Varon C, Chabas S, Chambonnier L, Darfeuille F, Staedel C. Helicobacter pylori initiates a mesenchymal transition through ZEB1 in gastric epithelial cells. PLoS One [Internet]. 2013;8:e60315. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23565224
The ASCO Post Staff. Oral Rinse Could Provide Early Screening for Gastric Cancer [Internet]. 2024 [cited 2024 Jul 11]. Available from: https://ascopost.com/news/may-2024/oral-rinse-could-provide-early-screening-for-gastric-cancer/
Liang Q, Chiu J, Chen Y, Huang Y, Higashimori A, Fang J, et al. Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer. Clin Cancer Res [Internet]. 2017;23:2061–70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27697996
Alkharaan H, Lu L, Gabarrini G, Halimi A, Ateeb Z, Sobkowiak MJ, et al. Circulating and Salivary Antibodies to Fusobacterium nucleatum Are Associated With Cystic Pancreatic Neoplasm Malignancy. Front Immunol [Internet]. 2020;11:2003. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32983143
Liu P-F, Shi W, Zhu W, Smith JW, Hsieh S-L, Gallo RL, et al. Vaccination targeting surface FomA of Fusobacterium nucleatum against bacterial co-aggregation: Implication for treatment of periodontal infection and halitosis. Vaccine [Internet]. 2010;28:3496–505. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20189489
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