Effects of Trazodone on Sleep: A Systematic Review and Meta-analysis

Morin CM, Jarrin DC. Epidemiology of insomnia: prevalence, course, risk factors, and public health burden. Sleep Med Clin. 2022;17(2):173–91.

Article  PubMed  Google Scholar 

Katz DA, McHorney CA. The relationship between insomnia and health-related quality of life in patients with chronic illness. J Fam Pract. 2002;51(3):229–35.

PubMed  Google Scholar 

Léger D, Guilleminault C, Bader G, Lévy E, Paillard M. Medical and socio-professional impact of insomnia. Sleep. 2002;25(6):625–9.

Article  PubMed  Google Scholar 

Fang H, Tu S, Sheng J, Shao A. Depression in sleep disturbance: a review on a bidirectional relationship, mechanisms and treatment. J Cell Mol Med. 2019;23(4):2324–32.

Article  PubMed  PubMed Central  Google Scholar 

Wang C, Holtzman DM. Bidirectional relationship between sleep and Alzheimer’s disease: role of amyloid, tau, and other factors. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol. 2020;45(1):104–20.

Article  CAS  Google Scholar 

Gottlieb DJ, Punjabi NM, Newman AB, Resnick HE, Redline S, Baldwin CM, et al. Association of sleep time with diabetes mellitus and impaired glucose tolerance. Arch Intern Med. 2005;165(8):863–7.

Article  PubMed  Google Scholar 

Meier-Ewert HK, Ridker PM, Rifai N, Regan MM, Price NJ, Dinges DF, et al. Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. J Am Coll Cardiol. 2004;43(4):678–83.

Article  CAS  PubMed  Google Scholar 

Medic G, Wille M, Hemels ME. Short- and long-term health consequences of sleep disruption. Nat Sci Sleep. 2017;9:151–61.

Article  PubMed  PubMed Central  Google Scholar 

Streatfeild J, Smith J, Mansfield D, Pezzullo L, Hillman D. The social and economic cost of sleep disorders. Sleep. 2021;44(11):zsab132.

Article  PubMed  Google Scholar 

Sateia MJ. International classification of sleep disorders-third edition. Chest. 2014;146(5):1387–94.

Article  PubMed  Google Scholar 

International Classification of Diseases, Eleventh Revision (ICD-11), World Health Organization (WHO) 2019/2021. Licensed under Creative Commons Attribution-NoDerivatives 3.0 IGOlicence (CC BY-ND 3.0 IGO). https://icd.who.int/browse11.

American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed. 2013. https://doi.org/10.1176/appi.books.9780890425596.

Poon SH, Quek SY, Lee TS. Insomnia disorders: nosology and classification past, present, and future. J Neuropsychiatry Clin Neurosci. 2021;33(3):194–200.

Article  PubMed  Google Scholar 

De Crescenzo F, D’Alò GL, Ostinelli EG, Ciabattini M, Di Franco V, Watanabe N, et al. Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis. Lancet Lond Engl. 2022;400(10347):170–84.

Article  Google Scholar 

Edinoff AN, Nix CA, Hollier J, Sagrera CE, Delacroix BM, Abubakar T, et al. Benzodiazepines: uses, dangers, and clinical considerations. Neurol Int. 2021;13(4):594–607.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Morin CM, Inoue Y, Kushida C, Poyares D, Winkelman J, Guidelines Committee Members, et al. Endorsement of European guideline for the diagnosis and treatment of insomnia by the World Sleep Society. Sleep Med. 2021;81:124–6.

Article  PubMed  Google Scholar 

Wang S, Lan Y, Liu Z, Xu S, Wu X. Effects of different interventions on insomnia in adults: systematic review and network meta-analysis. J Psychiatr Res. 2023;165:140–9.

Article  PubMed  Google Scholar 

Juul S, Gluud C, Simonsen S, Frandsen FW, Kirsch I, Jakobsen JC. Blinding in randomised clinical trials of psychological interventions: a retrospective study of published trial reports. BMJ Evid-Based Med. 2021;26(3):109.

Article  PubMed  Google Scholar 

Pelayo R, Bertisch SM, Morin CM, Winkelman JW, Zee PC, Krystal AD. Should trazodone be first-line therapy for insomnia? A clinical suitability appraisal. J Clin Med. 2023;12(8):2933.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Teva Pharmaceuticals USA, Inc. MEDICATION GUIDE trazodone hydrochloride. (2014). Revised 12/2018. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b48c8d16-ad28-47f2-9a85-4ef97bdd4bfc. Accessed 23 June 2024.

Gonçalo AMG, Vieira-Coelho MA. The effects of trazodone on human cognition: a systematic review. Eur J Clin Pharmacol. 2021;77(11):1623–37.

Article  PubMed  PubMed Central  Google Scholar 

Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017;13(02):307–49.

Article  PubMed  PubMed Central  Google Scholar 

Angelini Pharma Inc. OLEPTRO (trazodone hydrochloride) extended-release tablets Initial U.S. Approval: 1981 https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022411s008lbl.pdf. Reference ID: 3594617. Accessed 23 June 2024.

Fagiolini A, González-Pinto A, Miskowiak KW, Morgado P, Young AH, Vieta E. Role of trazodone in treatment of major depressive disorder: an update. Ann Gen Psychiatry. 2023;22(1):32.

Article  PubMed  PubMed Central  Google Scholar 

Jaffer KY, Chang T, Vanle B, Dang J, Steiner AJ, Loera N, et al. Trazodone for insomnia: a systematic review. Innov Clin Neurosci. 2017;14(7–8):24–34.

PubMed  PubMed Central  Google Scholar 

Wichniak A, Wierzbicka AE, Jarema M. Treatment of insomnia—effect of trazodone and hypnotics on sleep. Psychiatr Pol. 2021;55(4):743–55.

Article  PubMed  Google Scholar 

Everitt H, Baldwin DS, Stuart B, Lipinska G, Mayers A, Malizia AL, et al. Antidepressants for insomnia in adults. Cochrane Database Syst Rev. 2018;5(5):CD010753.

PubMed  Google Scholar 

Zheng Y, Lv T, Wu J, Lyu Y. Trazodone changed the polysomnographic sleep architecture in insomnia disorder: a systematic review and meta-analysis. Sci Rep. 2022;12(1):14453.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yi XY, Ni SF, Ghadami MR, Meng HQ, Chen MY, Kuang L, et al. Trazodone for the treatment of insomnia: a meta-analysis of randomized placebo-controlled trials. Sleep Med. 2018;45:25–32.

Article  PubMed  Google Scholar 

Moher D. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151(4):264.

Article  PubMed  Google Scholar 

Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14(6):540–5.

Article  CAS  PubMed  Google Scholar 

Hoddes E, Dement WC, Zarcone V. Stanford sleepiness scale (SSS) [Database record]. APA PsycTests. 1972. https://doi.org/10.1037/t07116-000.

Article  Google Scholar 

Reed DL, Sacco WP. Measuring sleep efficiency: what should the denominator be? J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med. 2016;12(2):263–6.

Google Scholar 

Dettori JR, Norvell DC, Chapman JR. Fixed-effect vs random-effects models for meta-analysis: 3 points to consider. Glob Spine J. 2022;12(7):1624–6.

Article  Google Scholar 

Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan—a web and mobile app for systematic reviews. Syst Rev. 2016;5(1):210.

Article  PubMed  PubMed Central  Google Scholar 

Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane handbook for systematic reviews of interventions version 6.4 (updated August 2023). Cochrane, 2023. www.training.cochrane.org/handbook.

Dong S, Schneider-Thoma J, Bighelli I, Siafis S, Wang D, Burschinski A, et al. A network meta-analysis of efficacy, acceptability, and tolerability of antipsychotics in treatment-resistant schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2024;274(4):917–28.

Article  PubMed  Google Scholar 

Samara MT, Dold M, Gianatsi M, Nikolakopoulou A, Helfer B, Salanti G, et al. Efficacy, acceptability, and tolerability of antipsychotics in treatment-resistant schizophrenia: a network meta-analysis. JAMA Psychiat. 2016;73(3):199–210.

Article 

留言 (0)

沒有登入
gif