The Role of Cannabinoids in Advancing Cancer Treatment: Insights from Evidence-Based Medicine

Ben AM. Cannabinoids in medicine: A review of their therapeutic potential. J Ethnopharmacol. 2006;105(1–2):1–25. https://doi.org/10.1016/j.jep.2006.02.001.

Article  CAS  Google Scholar 

Mack A, Joy J. In: Marijuana as Medicine? The Science Beyond the Controversy. Washington (DC): National Academies Press (US) Copyright 2001 by the National Academy of Sciences. All rights reserved.; 2000.

Odieka AE, Obuzor GU, Oyedeji OO, Gondwe M, Hosu YS, Oyedeji AO. The Medicinal Natural Products of Cannabis sativa Linn.: A Review. Molecules. 2022;27(5); https://doi.org/10.3390/molecules27051689

The Global Cannabis Report. https://newfrontierdata.com/global-cannabis/ (2024). Accessed.

Medical Marijuana Market Size, Share & Trends Analysis Report By Product Type (Flower, Oil & Tinctures), By Application (Chronic Pain, Arthritis, Migraine, Cancer, Diabetes, AIDS, Epilepsy, Parkinson’s Disease), By Region, And Segment Forecasts, 2023 - 2030. https://www.grandviewresearch.com/industry-analysis/medical-marijuana-market (2024). Accessed.

Finn DP, Haroutounian S, Hohmann AG, Krane E, Soliman N, Rice ASC. Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies. Pain. 2021;162(Suppl 1):S5-s25. https://doi.org/10.1097/j.pain.0000000000002268.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Romero-Sandoval EA, Kolano AL, Alvarado-Vázquez PA. Cannabis and Cannabinoids for Chronic Pain. Curr Rheumatol Rep. 2017;19(11):67. https://doi.org/10.1007/s11926-017-0693-1.

Article  CAS  PubMed  Google Scholar 

Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344–64. https://doi.org/10.1111/j.1476-5381.2011.01238.x.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Study shows Cannabis terpenes provide pain relief, contribute to 'entourage effect'. https://www.sciencedaily.com/releases/2021/07/210714110455.htm (2021). Accessed

Fisher E, Moore RA, Fogarty AE, Finn DP, Finnerup NB, Gilron I, et al. Cannabinoids, cannabis, and cannabis-based medicine for pain management: a systematic review of randomised controlled trials. Pain. 2021;162(Suppl 1):S45-s66. https://doi.org/10.1097/j.pain.0000000000001929.

Article  CAS  PubMed  Google Scholar 

Di Marzo V, Piscitelli F. The Endocannabinoid System and its Modulation by Phytocannabinoids. Neurotherapeutics. 2015;12(4):692–8. https://doi.org/10.1007/s13311-015-0374-6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ratcliffe E, Sunil M, Podinic T, Kasinska J, Hirota J, Raha S. A200 EXPOSURE TO CANNABIS SMOKE IN UTERO AFFECTS THE DEVELOPMENT OF THE ENDOCANNABINOID SYSTEM IN THE GASTROINTESTINAL TRACT. J Canadian Assoc Gastroenterol. 2024;7(Supplement_1):157–8. https://doi.org/10.1093/jcag/gwad061.200.

Article  Google Scholar 

Lu H-C, Mackie K. Review of the Endocannabinoid System. Biol Psychiatry: Cognitive Neuroscience Neuroimaging. 2021;6(6):607–15. https://doi.org/10.1016/j.bpsc.2020.07.016.

Article  Google Scholar 

Murru E, Manca C, Carta G, Ruggiu M, Solinas R, Montisci R, et al. Indirect Calorimetry-Based Novel Approach for Evaluating Metabolic Flexibility and Its Association with Circulating Metabolic Markers in Middle-Aged Subjects. Nutrients. 2024;16(4):525.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rutger SG, Mary BF, Kevin PB. Got the Munchies for an Egg Sandwich? The Effects of Cannabis on Bowel Motility and Beyond. Journal of Nuclear Medicine Technology. 2024:jnmt.123.266816; https://doi.org/10.2967/jnmt.123.266816

Hinz B, Ramer R. Cannabinoids as anticancer drugs: current status of preclinical research. Br J Cancer. 2022;127(1):1–13. https://doi.org/10.1038/s41416-022-01727-4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kienzl M, Hasenoehrl C, Maitz K, Sarsembayeva A, Taschler U, Valadez-Cosmes P, et al. Monoacylglycerol lipase deficiency in the tumor microenvironment slows tumor growth in non-small cell lung cancer. Oncoimmunology. 2021;10(1):1965319. https://doi.org/10.1080/2162402x.2021.1965319.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qiu C, Yang L, Wang B, Cui L, Li C, Zhuo Y, et al. The role of 2-arachidonoylglycerol in the regulation of the tumor-immune microenvironment in murine models of pancreatic cancer. Biomed Pharmacother. 2019;115:108952. https://doi.org/10.1016/j.biopha.2019.108952.

Article  CAS  PubMed  Google Scholar 

Glodde N, Jakobs M, Bald T, Tüting T, Gaffal E. Differential role of cannabinoids in the pathogenesis of skin cancer. Life Sci. 2015;138:35–40. https://doi.org/10.1016/j.lfs.2015.04.003.

Article  CAS  PubMed  Google Scholar 

Xiang W, Shi R, Kang X, Zhang X, Chen P, Zhang L, et al. Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression. Nat Commun. 2018;9(1):2574. https://doi.org/10.1038/s41467-018-04999-8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gruber T, Robatel S, Kremenovic M, Bäriswyl L, Gertsch J, Schenk M. Cannabinoid Receptor Type-2 in B Cells Is Associated with Tumor Immunity in Melanoma. Cancers (Basel). 2021;13(8); https://doi.org/10.3390/cancers13081934

Zaiachuk M, Pryimak N, Kovalchuk O, Kovalchuk I. Cannabinoids, Medical Cannabis, and Colorectal Cancer Immunotherapy. Front Med (Lausanne). 2021;8:713153. https://doi.org/10.3389/fmed.2021.713153.

Article  PubMed  Google Scholar 

Sarsembayeva A, Kienzl M, Gruden E, Ristic D, Maitz K, Valadez-Cosmes P, et al. Cannabinoid receptor 2 plays a pro-tumorigenic role in non-small cell lung cancer by limiting anti-tumor activity of CD8(+) T and NK cells. Front Immunol. 2022;13:997115. https://doi.org/10.3389/fimmu.2022.997115.

Article  CAS  PubMed  Google Scholar 

Laezza C, Pagano C, Navarra G, Pastorino O, Proto MC, Fiore D, et al. The Endocannabinoid System: A Target for Cancer Treatment. Int J Mol Sci. 2020;21(3); https://doi.org/10.3390/ijms21030747

Anderson NM, Simon MC. The tumor microenvironment. Curr Biol. 2020;30(16):R921–5. https://doi.org/10.1016/j.cub.2020.06.081.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sheik A, Farani MR, Kim E, Kim S, Gupta VK, Kumar K, et al. Therapeutic targeting of the tumor microenvironments with cannabinoids and their analogs: Update on clinical trials. Environ Res. 2023;231(Pt 1):115862. https://doi.org/10.1016/j.envres.2023.115862.

Article  CAS  PubMed  Google Scholar 

O’Brien K. Medicinal Cannabis: Issues of evidence. European Journal of Integrative Medicine. 2019;28:114–20. https://doi.org/10.1016/j.eujim.2019.05.009.

Article  Google Scholar 

Sackett DL, Rosenberg WMC, Gray JAM, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn’t. BMJ. 1996;312(7023):71–2. https://doi.org/10.1136/bmj.312.7023.71.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sallan SE, Zinberg NE, Frei E 3rd. Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy. N Engl J Med. 1975;293(16):795–7. https://doi.org/10.1056/nejm197510162931603.

Article  CAS  PubMed  Google Scholar 

Kluin-Neleman JC, Neleman FA, Meuwissen OJ, Maes RA. delta 9-Tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancerchemotherapy; a double-blind cross-over trial against placebo. Vet Hum Toxicol. 1979;21(5):338–40.

CAS  PubMed  Google Scholar 

Zutt M, Hänssle H, Emmert S, Neumann C, Kretschmer L. Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases. Hautarzt. 2006;57(5):423–7. https://doi.org/10.1007/s00105-005-1063-x.

Article  CAS  PubMed  Google Scholar 

Meiri E, Jhangiani H, Vredenburgh JJ, Barbato LM, Carter FJ, Yang HM, et al. Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. Curr Med Res Opin. 2007;23(3):533–43. https://doi.org/10.1185/030079907x167525.

Article  CAS  PubMed  Google Scholar 

Duran M, Pérez E, Abanades S, Vidal X, Saura C, Majem M, et al. Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting. Br J Clin Pharmacol. 2010;70(5):656–63. https://doi.org/10.1111/j.1365-2125.2010.03743.x.

Article  CAS  PubMed  PubMed Central  Google Scholar 

留言 (0)

沒有登入
gif