Allen RJ, Guillen-Guio B, Oldham JM, Ma SF, Dressen A, Paynton ML, Kraven LM, Obeidat M, Li X, Ng M, Braybrooke R, Molina-Molina M, Hobbs BD, Putman RK, Sakornsakolpat P, Booth HL, Fahy WA, Hart SP, Hill MR, Hirani N, Hubbard RB, McAnulty RJ, Millar AB, Navaratnam V, Oballa E, Parfrey H, Saini G, Whyte MKB, Zhang Y, Kaminski N, Adegunsoye A, Strek ME, Neighbors M, Sheng XR, Gudmundsson G, Gudnason V, Hatabu H, Lederer DJ, Manichaikul A, Newell JD Jr., O’Connor GT, Ortega VE, Xu H, Fingerlin TE, Bosse Y, Hao K, Joubert P, Nickle DC, Sin DD, Timens W, Furniss D, Morris AP, Zondervan KT, Hall IP, Sayers I, Tobin MD, Maher TM, Cho MH, Hunninghake GM, Schwartz DA, Yaspan BL, Molyneaux PL, Flores C, Noth I, Jenkins RG, Wain LV (2020) Genome-Wide Association Study of Susceptibility to idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 201:564–574. https://doi.org/10.1164/rccm.201905-1017OC
Article PubMed CAS Google Scholar
An J, Gharahkhani P, Law MH, Ong JS, Han X, Olsen CM, Neale RE, Lai J, Vaughan TL, Gockel I, Thieme R, Bohmer AC, Jankowski J, Fitzgerald RC, Schumacher J, Palles C, Beacon T, Whiteman DC, MacGregor S (2019) Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases. Nat Commun 10: 4219. https://doi.org/10.1038/s41467-019-11968-2
Aragam KG, Jiang T, Goel A, Kanoni S, Wolford BN, Atri DS, Weeks EM, Wang M, Hindy G, Zhou W, Grace C, Roselli C, Marston NA, Kamanu FK, Surakka I, Venegas LM, Sherliker P, Koyama S, Ishigaki K, Asvold BO, Brown MR, Brumpton B, de Vries PS, Giannakopoulou O, Giardoglou P, Gudbjartsson DF, Guldener U, Haider SMI, Helgadottir A, Ibrahim M, Kastrati A, Kessler T, Kyriakou T, Konopka T, Li L, Ma L, Meitinger T, Mucha S, Munz M, Murgia F, Nielsen JB, Nothen MM, Pang S, Reinberger T, Schnitzler G, Smedley D, Thorleifsson G, von Scheidt M, Ulirsch JC, Biobank J, Epic CVD, Arnar DO, Burtt NP, Costanzo MC, Flannick J, Ito K, Jang DK, Kamatani Y, Khera AV, Komuro I, Kullo IJ, Lotta LA, Nelson CP, Roberts R, Thorgeirsson G, Thorsteinsdottir U, Webb TR, Baras A, Bjorkegren JLM, Boerwinkle E, Dedoussis G, Holm H, Hveem K, Melander O, Morrison AC, Orho-Melander M, Rallidis LS, Ruusalepp A, Sabatine MS, Stefansson K, Zalloua P, Ellinor PT, Farrall M, Danesh J, Ruff CT, Finucane HK, Hopewell JC, Clarke R, Gupta RM, Erdmann J, Samani NJ, Schunkert H, Watkins H, Willer CJ, Deloukas P, Kathiresan S, Butterworth AS, Consortium CAD (2022) Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants. Nat Genet 54:1803–1815. https://doi.org/10.1038/s41588-022-01233-6
Article PubMed PubMed Central CAS Google Scholar
Assou S, Boumela I, Haouzi D, Anahory T, Dechaud H, De Vos J, Hamamah S (2011) Dynamic changes in gene expression during human early embryo development: from fundamental aspects to clinical applications. Hum Reprod Update 17:272–290. https://doi.org/10.1093/humupd/dmq036
Article PubMed CAS Google Scholar
Bosse KR, Raman P, Zhu Z, Lane M, Martinez D, Heitzeneder S, Rathi KS, Kendsersky NM, Randall M, Donovan L, Morrissy S, Sussman RT, Zhelev DV, Feng Y, Wang Y, Hwang J, Lopez G, Harenza JL, Wei JS, Pawel B, Bhatti T, Santi M, Ganguly A, Khan J, Marra MA, Taylor MD, Dimitrov DS, Mackall CL, Maris JM (2017) Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma. Cancer Cell 32: 295–309 e12. https://doi.org/10.1016/j.ccell.2017.08.003
Bowden J, Davey Smith G, Haycock PC, Burgess S (2016) Consistent estimation in mendelian randomization with some Invalid instruments using a weighted median estimator. Genet Epidemiol 40:304–314. https://doi.org/10.1002/gepi.21965
Article PubMed PubMed Central Google Scholar
Breccia M, Salaroli A, Serrao A, Zacheo I, Alimena G (2013) Imatinib induces body mass changes in women with chronic myeloid leukemia. Ann Hematol 92:1581–1582. https://doi.org/10.1007/s00277-013-1752-y
Breton J, Galmiche M, Dechelotte P (2022) Dysbiotic gut Bacteria in obesity: an overview of the metabolic mechanisms and therapeutic perspectives of Next-Generation Probiotics. Microorganisms 10. https://doi.org/10.3390/microorganisms10020452
Bulik-Sullivan B, Finucane HK, Anttila V, Gusev A, Day FR, Loh PR, ReproGen C, Psychiatric Genomics C, Genetic Consortium for Anorexia Nervosa of the Wellcome Trust Case, Control C, Duncan L, Perry JR, Patterson N, Robinson EB, Daly MJ, Price AL, Neale BM (2015) An atlas of genetic correlations across human diseases and traits. Nat Genet 47:1236–1241. https://doi.org/10.1038/ng.3406
Article PubMed PubMed Central CAS Google Scholar
Burgess S, Thompson SG (2017) Interpreting findings from mendelian randomization using the MR-Egger method. Eur J Epidemiol 32:377–389. https://doi.org/10.1007/s10654-017-0255-x
Article PubMed PubMed Central Google Scholar
Burgess S, Butterworth A, Thompson SG (2013) Mendelian randomization analysis with multiple genetic variants using summarized data. Genet Epidemiol 37:658–665. https://doi.org/10.1002/gepi.21758
Article PubMed PubMed Central Google Scholar
Byrne EM, Zhu Z, Qi T, Skene NG, Bryois J, Pardinas AF, Stahl E, Smoller JW, Rietschel M, Bipolar Working Group of the Psychiatric Genomics C, Major Depressive Disorder Working Group of the Psychiatric, Genomics C, Owen MJ, Walters JTR, O’Donovan MC, McGrath JG, Hjerling-Leffler J, Sullivan PF, Goddard ME, Visscher PM, Yang J, Wray NR (2020) Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Mol Psychiatry doi. https://doi.org/10.1038/s41380-020-0705-9
Caminati A, Lonati C, Cassandro R, Elia D, Pelosi G, Torre O, Zompatori M, Uslenghi E, Harari S (2019) Comorbidities in idiopathic pulmonary fibrosis: an underestimated issue. Eur Respir Rev 28. https://doi.org/10.1183/16000617.0044-2019
Chennakesavulu S, Mishra A, Sudheer A, Sowmya C, Suryaprakash Reddy C, Bhargav E (2018) Pulmonary delivery of liposomal dry powder inhaler formulation for effective treatment of idiopathic pulmonary fibrosis. Asian J Pharm Sci 13:91–100. https://doi.org/10.1016/j.ajps.2017.08.005
Article PubMed CAS Google Scholar
Chioma OS, Hesse LE, Chapman A, Drake WP (2021) Role of the Microbiome in interstitial Lung diseases. Front Med (Lausanne) 8:595522. https://doi.org/10.3389/fmed.2021.595522
Chiorazzi N, Ferrarini M (2011) Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities. Blood 117:1781–1791. https://doi.org/10.1182/blood-2010-07-155663
Article PubMed PubMed Central CAS Google Scholar
Cobo ER, Kissoon-Singh V, Moreau F, Chadee K (2015) Colonic MUC2 mucin regulates the expression and antimicrobial activity of beta-defensin 2. Mucosal Immunol 8:1360–1372. https://doi.org/10.1038/mi.2015.27
Article PubMed PubMed Central CAS Google Scholar
Comes A, Wong AW, Fisher JH, Morisset J, Johannson KA, Farrand E, Fell CD, Kolb M, Manganas H, Cox G, Gershon AS, Halayko AJ, Hambly N, Khalil N, Sadatsafavi M, Shapera S, To T, Wilcox PG, Collard HR, Ryerson CJ (2022) Association of BMI and change in Weight with mortality in patients with fibrotic interstitial lung disease. Chest 161:1320–1329. https://doi.org/10.1016/j.chest.2021.11.008
Cotton C, Alton P, Hughes DM, Zhao SS (2023) Genetic liability to gastro-esophageal reflux disease, obesity, and risk of idiopathic pulmonary fibrosis. Respir Investig 61:335–338. https://doi.org/10.1016/j.resinv.2023.02.005
Article PubMed CAS Google Scholar
Daniels CE, Lasky JA, Limper AH, Mieras K, Gabor E, Schroeder DR, Imatinib IPFSI (2010) Imatinib treatment for idiopathic pulmonary fibrosis: randomized placebo-controlled trial results. Am J Respir Crit Care Med 181:604–610. https://doi.org/10.1164/rccm.200906-0964OC
Article PubMed CAS Google Scholar
Davies NM, Holmes MV, Davey Smith G (2018) Reading mendelian randomisation studies: a guide, glossary, and checklist for clinicians. BMJ 362:k601. https://doi.org/10.1136/bmj.k601
Article PubMed PubMed Central Google Scholar
Deidda A, Pisanu C, Micheletto L, Bocchetta A, Del Zompo M, Stochino ME (2017) Interstitial lung disease induced by fluoxetine: systematic review of literature and analysis of Vigiaccess, Eudravigilance and a national pharmacovigilance database. Pharmacol Res 120:294–301. https://doi.org/10.1016/j.phrs.2017.04.010
Article PubMed CAS Google Scholar
Distler JH, Distler O (2007) Cardiotoxicity of imatinib mesylate: an extremely rare phenomenon or a major side effect? Ann Rheum Dis 66:836. https://doi.org/10.1136/ard.2006.067710
Article PubMed PubMed Central Google Scholar
Fernandez Perez ER, Daniels CE, Schroeder DR, St Sauver J, Hartman TE, Bartholmai BJ, Yi ES, Ryu JH (2010) Incidence, prevalence, and clinical course of idiopathic pulmonary fibrosis: a population-based study. Chest 137:129–137. https://doi.org/10.1378/chest.09-1002
Forno E, Lescher R, Strunk R, Weiss S, Fuhlbrigge A, Celedon JC, Childhood Asthma Management Program Research G (2011) Decreased response to inhaled steroids in overweight and obese asthmatic children. J Allergy Clin Immunol 127:741–749. https://doi.org/10.1016/j.jaci.2010.12.010
Article PubMed PubMed Central CAS Google Scholar
Freshour SL, Kiwala S, Cotto KC, Coffman AC, McMichael JF, Song JJ, Griffith M, Griffith OL, Wagner AH (2021) Integration of the Drug-Gene Interaction database (DGIdb 4.0) with open crowdsource efforts. Nucleic Acids Res 49:D1144–D1151. https://doi.org/10.1093/nar/gkaa1084
Article PubMed CAS Google Scholar
Ge SX, Jung D, Yao R (2020) ShinyGO: a graphical gene-set enrichment tool for animals and plants. Bioinformatics 36:2628–2629. https://doi.org/10.1093/bioinformatics/btz931
Article PubMed CAS Google Scholar
Ghebre YT (2018) Proton Pump inhibitors in IPF: a call for clinical trials. Front Pharmacol 9:499.
留言 (0)