WHO Classification of Tumours Editoral Board (2019) Breast tumours. Lyon: Int Agency Res Cancer

Veronesi U, Cascinelli N, Mariani L, Greco M, Saccozzi R, Luini A et al (2002) Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med 347(16):1227–1232

Article  PubMed  Google Scholar 

UICC (Union for International Cancer Control) (2017) TNM Classification of Malignant Tumours, 8th edn, Brierley JD, Gospadarowicz MK, Wittekind C (eds). Oxford: Wiley Blackwell

UICC (Union for International Cancer Control) (2019) TNM Supplement. A commentary on uniform use, 5th edn, Wittekind Ch, Brierley JD, Lee A.W.M. Eycken, E. (eds). Hoboken: Wiley Blackwell

UICC (Union for International Cancer Control) (1993) TNM Supplement 1993. A Commentary on Uniform Use, Hermanek P, Henson DE, Hutter RVP, Sohin LH (eds). Berlin, Heidelberg, New York: Springer

Wittekind C, Compton CC, Greene FL, Sobin LH (2002) TNM residual tumor classification revisited. Cancer 94(9):2511–2516

Article  PubMed  Google Scholar 

Wittekind C (2007) Problems with residual tumor classification, particularly R1. Chirurg 78(9):785–791

Article  PubMed  CAS  Google Scholar 

Hermanek P, Wittekind C (1994) Residual tumor (R) classification and prognosis. Semin Surg Oncol 10(1):12–20

Article  PubMed  CAS  Google Scholar 

Hermanek P, Wittekind C (1994) The pathologist and the residual tumor (R) classification. Pathol Res Pract 190(2):115–123

Article  PubMed  CAS  Google Scholar 

Wittekind C, Compton C, Quirke P, Nagtegaal I, Merkel S, Hermanek P et al (2009) A uniform residual tumor (R) classification: integration of the R classification and the circumferential margin status. Cancer 115(15):3483–3488

Article  PubMed  Google Scholar 

Bundred JR, Michael S, Stuart B, Cutress RI, Beckmann K, Holleczek B et al (2022) Margin status and survival outcomes after breast cancer conservation surgery: prospectively registered systematic review and meta-analysis. BMJ 378:e070346

Article  PubMed  PubMed Central  Google Scholar 

Houssami N, Macaskill P, Marinovich ML, Morrow M (2014) The association of surgical margins and local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy: a meta-analysis. Ann Surg Oncol 21(3):717–730

Article  PubMed  PubMed Central  Google Scholar 

Brouwer de Koning SG, VranckenPeeters M, Jozwiak K, Bhairosing PA, Ruers TJM (2018) Tumor resection margin definitions in breast-conserving surgery: systematic review and meta-analysis of the current literature. Clin Breast Cancer 18(4):e595–e600

Article  PubMed  Google Scholar 

Haloua MH, Volders JH, Krekel NM, Barbe E, Sietses C, Jozwiak K et al (2016) A nationwide pathology study on surgical margins and excision volumes after breast-conserving surgery: There is still much to be gained. Breast 25:14–21

Article  PubMed  CAS  Google Scholar 

Pilewskie M, Morrow M (2018) Margins in breast cancer: how much is enough? Cancer 124(7):1335–1341

Article  PubMed  Google Scholar 

Evidence-based guideline for the early detection, diagnosis, treatment and follow-up of breast cancer: German Guideline Program in Oncology (German Cancer Society, German Cancer Aid, AWMF); 2021 [Available from: https://www.leitlinienprogramm-onkologie.de/leitlinien/mammakarzinom/

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Breast Cancer: National Comprehensive Cancer Network; 2022 [Available from: https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf

Consensus guideline on breast cancer lumpectomy margins: the American Society of Breast Surgeons; 2017 [Available from: https://www.breastsurgeons.org/docs/statements/Consensus-Guideline-on-Breast-Cancer-Lumpectomy-Margins.pdf

Burstein HJ, Curigliano G, Loibl S, Dubsky P, Gnant M, Poortmans P et al (2019) Estimating the benefits of therapy for early-stage breast cancer: the St. Gallen International Consensus Guidelines for the primary therapy of early breast cancer 2019. Ann Oncol 30(10):1541–57

Article  PubMed  CAS  Google Scholar 

Moran MS, Schnitt SJ, Giuliano AE, Harris JR, Khan SA, Horton J et al (2014) Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. Int J Radiat Oncol Biol Phys 88(3):553–564

Article  PubMed  PubMed Central  Google Scholar 

Morrow M, Van Zee KJ, Solin LJ, Houssami N, Chavez-MacGregor M, Harris JR et al (2016) Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for breast-conserving surgery with whole-breast irradiation in ductal carcinoma in situ. Pract Radiat Oncol 6(5):287–295

Article  PubMed  PubMed Central  Google Scholar 

Maloney BW, McClatchy DM, Pogue BW, Paulsen KD, Wells WA, Barth RJ (2018) Review of methods for intraoperative margin detection for breast conserving surgery. J Biomed Opt 23(10):1–19

Article  PubMed  Google Scholar 

Buchholz TA, Somerfield MR, Griggs JJ, El-Eid S, Hammond ME, Lyman GH et al (2014) Margins for breast-conserving surgery with whole-breast irradiation in stage I and II invasive breast cancer: American Society of Clinical Oncology endorsement of the Society of Surgical Oncology/American Society for Radiation Oncology consensus guideline. J Clin Oncol 32(14):1502–1506

Article  PubMed  Google Scholar 

Tremelling A, Aft RL, Cyr AE, Gillanders WE, Glover-Collins K, Herrmann V et al (2022) Impact of consensus guidelines for breast-conserving surgery in patients with ductal carcinoma in situ. Cancer Rep (Hoboken) 5(5):e1502

Article  PubMed  Google Scholar 

Statistik Austria; Accessed January 3, 2023[Available from: https://www.statistik.at/statistiken/bevoelkerung-und-soziales/bevoelkerung/bevoelkerungsstand/bevoelkerung-zu-jahres-/-quartalsanfang

Statistische Ämter des Bundes und der Länder; Accessed January 3, 2023[Available from: https://www.statistikportal.de/de/bevoelkerung/flaeche-und-bevoelkerung

Fischer P, Differences in the interpretation of the R classification -with a special focus on breast cancer, Master’s Thesis approved by Med Uni Graz, 2023

LimeSurvey GmbH; 2021 [Available from: https://www.limesurvey.org/de/

Fox S, Chen CJ, Chua B, Collins LC, Foschini MP, Mann B, Millar EKA, Pinder S, Rakha E, Shaaban AM, Tan BY, Tse GM, Watson PH, Tan PH (2021) Ductal carcinoma in situ, variants of lobular carcinoma in situ and low grade lesions histopathology reporting guide. International Collaboration on Cancer Reporting; Sydney, Australia

Ellis I, Allison KH, Dang C, Gobbi H, Kulka J, Lakhani SR, Moriya T, Quinn CM, Sapino A, Schnitt S, Sibbering DM, Slodkowska E, Yang W, Tan PH (2022) Invasive carcinoma of the breast histopathology reporting guide, 2nd edition. International Collaboration on Cancer Reporting; Sydney, Australia

Bossuyt V, Provenzano E, Symmans WF, Allison KH, Dang C, Gobbi H, Kulka J, Lakhani SR, Moriya T, Quinn CM, Sapino A, Schnitt S, Sibbering DM, Slodkowska E, Yang W, Tan PH, Ellis I (2022) Invasive carcinoma of the breast in the setting of neoadjuvant therapy histopathology reporting guide, 1st edition. International Collaboration on Cancer Reporting; Sydney, Australia

Marinovich ML, Azizi L, Petra Macaskill P, Les Irwig L, Monica Morrow M, Solin LJ, Houssami N (2016) The association of surgical margins and local recurrence in women with ductal carcinoma in situ treated with breast-conserving therapy: a meta-analysis. Ann Surg Oncol 23(12):3811–3821

Article  PubMed  PubMed Central  Google Scholar 

Holland R, Veling SH, Mravunac M, Hendriks JH (1985) Histologic multifocality of Tis, T1-2 breast carcinomas. Implications for clinical trials of breast-conserving surgery. Cancer 56(5):979–90

Article  PubMed  CAS  Google Scholar 

Faverly DR, Burgers L, Bult P, Holland R (1994) Three dimensional imaging of mammary ductal carcinoma in situ: clinical implications. Semin Diagn Pathol 11(3):193–198

PubMed  CAS  Google Scholar 

Carter D (1986) Margins of “lumpectomy” for breast cancer. Hum Pathol 17(4):330–332

Article  PubMed  CAS  Google Scholar 

Rami-Porta R, Wittekind C, Goldstraw P, International Association for the Study of Lung Cancer Staging C (2005) Complete resection in lung cancer surgery: proposed definition. Lung Cancer 49(1):25–33

Article  PubMed  Google Scholar 

Gagliasso M, Migliaretti G, Ardissone F (2017) Assessing the prognostic impact of the International Association for the Study of Lung Cancer proposed definitions of complete, uncertain, and incomplete resection in non-small cell lung cancer surgery. Lung Cancer 111:124–130

Article  PubMed  Google Scholar 

UICC (Union for International Cancer Control) TNM Help desk; Accessed December 20, 2022[Available from: https://www.uicc.org/tnm-help-desk