We thank E. Del Boca and staff members from Achelois for coordinating this conference, and thank EMBO, GSK, JPT, Journal of Experimental Medicine, InvivoGen, Cytek, Disease Models & Mechanisms and PHSE for sponsoring the conference. We also thank the invited speakers and participants for sharing their valuable knowledge and perspectives on infection and immunity. In addition, we express our gratitude to the invited speakers who allowed us to incorporate their research into this meeting report, and apologize to presenters whose work could not be discussed due to space constraints.