Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL. D.C. Angus, the Third International Consensus definitions for Sepsis and septic shock (Sepsis-3). JAMA 2016;315(8):801– 10.
Rudd KE, Johnson SC, Agesa KM, Shackelford KA, Tsoi D, Kievlan DR, Colombara DV, Ikuta KS, Kissoon N, Finfer S, Fleischmann-Struzek C, Machado FR, Reinhart KK, Rowan K, Seymour CW, Watson RS, West TE, Marinho F, Hay SI, Lozano R, Lopez AD, Angus DC, Murray CJL, Naghavi M. Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the global burden of Disease Study. Lancet. 2020;395(10219):200–11.
Article PubMed PubMed Central Google Scholar
Sun X, Liu Y, Wang J, Zhang M, Wang M. Cardioprotection of M2 macrophages-derived exosomal microRNA-24-3p/Tnfsf10 axis against myocardial injury after sepsis. Mol Immunol. 2021;141:309–17.
Lee SM, Son KN, Shah D, Ali M, Balasubramaniam A, Shukla D, Aakalu VK. Histatin-1 attenuates LPS-Induced Inflammatory Signaling in RAW264.7 macrophages. Int J Mol Sci 2021;22(15):.
Sakamaki I, Fukushi M, Ohashi W, Tanaka Y, Itoh K, Tomihara K, Yamamoto Y, Iwasaki H. Sitafloxacin reduces tumor necrosis factor alpha (TNFalpha) converting enzyme (TACE) phosphorylation and activity to inhibit TNFalpha release from lipopolysaccharide-stimulated THP-1 cells. Sci Rep. 2021;11(1):24154.
Article CAS PubMed PubMed Central Google Scholar
Lopez-Bojorquez LN, Dehesa AZ, Reyes-Teran G. Molecular mechanisms involved in the pathogenesis of septic shock. Arch Med Res. 2004;35(6):465–79.
Article CAS PubMed Google Scholar
Biswas SK, Lopez-Collazo E. Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol. 2009;30(10):475–87.
Article CAS PubMed Google Scholar
Ha M, Kim VN. Regulation of microRNA biogenesis. Nat Rev Mol Cell Biol. 2014;15(8):509–24.
Article CAS PubMed Google Scholar
Stavast CJ, Erkeland SJ. The non-canonical aspects of MicroRNAs: many roads to Gene Regulation. Cells 2019;8(11).
Wang J, Song J, Li Y, Shao J, Xie Z, Sun K. Down-regulation of LncRNA CRNDE aggravates kidney injury via increasing MiR-181a-5p in sepsis. Int Immunopharmacol. 2020;79:105933.
Article CAS PubMed Google Scholar
Wang S, Yang Y, Suen A, Zhu J, Williams B, Hu J, Chen F, Kozar R, Shen S, Li Z, Jeyaram A, Jay SM, Zou L, Chao W. Role of extracellular microRNA-146a-5p in host innate immunity and bacterial sepsis. iScience. 2021;24(12):103441.
Article CAS PubMed PubMed Central Google Scholar
Chen W, Gao G, Yan M, Yu M, Shi K, Yang P. Long noncoding RNA MAPKAPK5-AS1 promoted lipopolysaccharide-induced inflammatory damage in the myocardium by sponging microRNA-124-3p/E2F3. Mol Med. 2021;27(1):131.
Article PubMed PubMed Central Google Scholar
Yao Y, Xu K, Sun Y, Tian T, Shen W, Sun F, Yuan W, Wu H, Chen G, Yuan L, Zhang W, Lu M, Lei M. MiR-215-5p inhibits the inflammation injury in septic H9c2 by regulating ILF3 and LRRFIP1. Int Immunopharmacol. 2020;78:106000.
Article CAS PubMed Google Scholar
Dennis EA, Cao J, Hsu YH, Magrioti V, Kokotos G. Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention. Chem Rev. 2011;111(10):6130–85.
Article CAS PubMed Google Scholar
Huang F, Wang K, Shen J. Lipoprotein-associated phospholipase A2: the story continues. Med Res Rev. 2020;40(1):79–134.
Article CAS PubMed Google Scholar
Zalewski A, Macphee C. Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target. Arterioscler Thromb Vasc Biol. 2005;25(5):923–31.
Article CAS PubMed Google Scholar
Staurenghi G, Ye L, Magee MH, Danis RP, Wurzelmann J, Adamson P, McLaughlin MM, Darapladib DMESG. Darapladib, a lipoprotein-associated phospholipase A2 inhibitor, in diabetic macular edema: a 3-month placebo-controlled study. Ophthalmology. 2015;122(5):990–6.
Huang Z, Jiang H, Cui X, Liang G, Chen Y, Wang T, Sun Z, Qi L. Elevated serum levels of lipoprotein–associated phospholipase A2 predict mortality rates in patients with sepsis. Mol Med Rep. 2018;17(1):1791–8.
Tucureanu MM, Rebleanu D, Constantinescu CA, Deleanu M, Voicu G, Butoi E, Calin M, Manduteanu I. Lipopolysaccharide-induced inflammation in monocytes/macrophages is blocked by liposomal delivery of Gi-protein inhibitor. Int J Nanomed. 2018;13:63–76.
He W, Qu T, Yu Q, Wang Z, Lv H, Zhang J, Zhao X, Wang P. LPS induces IL-8 expression through TLR4, MyD88, NF-kappaB and MAPK pathways in human dental pulp stem cells. Int Endod J. 2013;46(2):128–36.
Article CAS PubMed Google Scholar
Lee HN, Shin SA, Choo GS, Kim HJ, Park YS, Kim BS, Kim SK, Cho SD, Nam JS, Choi CS, Che JH, Park BK, Jung JY. Antiinflammatory effect of quercetin and galangin in LPSstimulated RAW264.7 macrophages and DNCBinduced atopic dermatitis animal models. Int J Mol Med. 2018;41(2):888–98.
Boda SK, Aparicio C. Dual keratinocyte-attachment and anti-inflammatory coatings for soft tissue sealing around transmucosal oral implants. Biomaterials Sci. 2022.
Zhang H, Zhang M, Wang X, Zhang M, Wang X, Li Y, Cui Z, Chen X, Han Y, Zhao W. Electrospun multifunctional nanofibrous mats loaded with bioactive anemoside B4 for accelerated wound healing in diabetic mice. Drug Delivery. 2022;29(1):174–85.
Article CAS PubMed Google Scholar
Jiang X, Xu J, Hao X, Xue J, Li K, Jin A, Lin J, Meng X, Zheng L, Wang Y. Elevated lipoprotein(a) and lipoprotein-associated phospholipase A2 are associated with unfavorable functional outcomes in patients with ischemic stroke. J Neuroinflamm. 2021;18(1):307.
Mouchlis VD, Hayashi D, Vasquez AM, Cao J, McCammon JA, Dennis EA. Lipoprotein-associated phospholipase A2: a paradigm for allosteric regulation by membranes. Proc Natl Acad Sci USA 119(2). 2022.
Lv SL, Zeng ZF, Gan WQ, Wang WQ, Li TG, Hou YF, Yan Z, Zhang RX, Yang M. Lp-PLA2 inhibition prevents Ang II-induced cardiac inflammation and fibrosis by blocking macrophage NLRP3 inflammasome activation. Acta Pharmacol Sin. 2021;42(12):2016–32.
Article CAS PubMed Google Scholar
Deng M, Yin Y, Zhang Q, Zhou X, Hou G. Identification of inflammation-related Biomarker Lp-PLA2 for patients with COPD by Comprehensive Analysis. Front Immunol. 2021;12:670971.
Article CAS PubMed Google Scholar
Ghafouri-Fard S, Khoshbakht T, Hussen BM, Taheri M, Arefian N. Regulatory Role of non-coding RNAs on Immune responses during Sepsis. Front Immunol. 2021;12:798713.
Article CAS PubMed Google Scholar
Abdelaleem OO, Mohammed SR, El HS, Sayed SK, Hussein DY, Ali MY, Abdelwahed SN, Gaber NF, Hemeda RGA. El-Hmid, serum miR-34a-5p and miR-199a-3p as new biomarkers of neonatal sepsis. PLoS ONE. 2022;17(1):e0262339.
Article CAS PubMed Google Scholar
Juzenas S, Hubenthal M, Lindqvist CM, Kruse R, Steiert TA, Degenhardt F, Schulte D, Nikolaus S, Zeissig S, Bergemalm D, Almer S, Hjortswang H, Bresso F, Struning N, Kupcinskas J, Keller A, Lieb W, Rosenstiel P, Schreiber S, D’Amato M, Halfvarson J, Hemmrich-Stanisak G, Franke A. Detailed transcriptional landscape of peripheral blood points to increased neutrophil activation in treatment-naive inflammatory bowel disease, Journal of Crohn’s & colitis. 2022.
Jiao Y, Zhang T, Zhang C, Ji H, Tong X, Xia R, Wang W, Ma Z, Shi X. Exosomal miR-30d-5p of neutrophils induces M1 macrophage polarization and primes macrophage pyroptosis in sepsis-related acute lung injury. Crit Care. 2021;25(1):356.
Article PubMed PubMed Central Google Scholar
Wang J, Wang X, Ma X, Xu B, Chen L, Chen C, Liu W, Liu Y, Xiang Z. Therapeutic effect of Patrinia villosa on TNBS-induced ulcerative colitis via metabolism, vitamin D receptor and NF-kappaB signaling pathways. J Ethnopharmacol 2022; 114989.
Abd El-Fattah EE, Saber S, Mourad AAE, El-Ahwany E, Amin NA, Cavalu S, Yahya G, Saad AS, Alsharidah M, Shata A, Sami HM, Kaddah MMY, Ghanim AMH. The dynamic interplay between AMPK/NFkappaB signaling and NLRP3 is a new therapeutic target in inflammation: emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury. Volume 147. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie; 2022. p. 112628.
Rao Z, Zeng J, Li X, Peng L, Wang B, Luan F, Zeng N. JFNE-A isolated from Jing-Fang n-butanol extract attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress and the NF-kappaB signaling pathway via promotion of autophagy. Phytomedicine: Int J Phytotherapy Phytopharmacology. 2021;96:153891.
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