Possible Drug Repurposing and Accelerated Wound Healing

Wilkinson HN, Hardman MJ. Wound healing: cellular mechanisms and pathological outcomes. Open Biol. 2020;10(9):200223. https://doi.org/10.1098/rsob.200223.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wallace HA, Basehore BM, Zito PM, “Wound healing phases,” in StatPearls, Treasure Island (FL): StatPearls Publishing, 2023. Accessed: Aug. 11, 2023. [Online]. Available: http://www.ncbi.nlm.nih.gov/books/NBK470443/

Polcz ME, Barbul A. The role of vitamin A in wound healing. Nutr Clin Pract Off Publ Am Soc Parenter Enter Nutr. 2019;34(5):695–700. https://doi.org/10.1002/ncp.10376.

Article  CAS  Google Scholar 

Oda Y, Tu C-L, Menendez A, Nguyen T, Bikle DD. Vitamin D and calcium regulation of epidermal wound healing. J Steroid Biochem Mol Biol. 2016;164:379–85. https://doi.org/10.1016/j.jsbmb.2015.08.011.

Article  CAS  PubMed  Google Scholar 

Pazyar N, Houshmand G, Yaghoobi R, Hemmati AA, Zeineli Z, Ghorbanzadeh B. Wound healing effects of topical Vitamin K: a randomized controlled trial. Indian J Pharmacol. 2019;51(2):88–92. https://doi.org/10.4103/ijp.IJP_183_18.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hu H, et al. Angiogenesis and full-thickness wound healing efficiency of a copper-doped borate bioactive glass/poly(lactic- co-glycolic acid) dressing loaded with vitamin E in vivo and in vitro. ACS Appl Mater Interfaces. 2018;10(27):22939–50. https://doi.org/10.1021/acsami.8b04903.

Article  CAS  PubMed  Google Scholar 

Avishai E, Yeghiazaryan K, Golubnitschaja O. Impaired wound healing: facts and hypotheses for multi-professional considerations in predictive, preventive and personalised medicine. EPMA J. 2017;8(1):23–33. https://doi.org/10.1007/s13167-017-0081-y.

Article  PubMed  PubMed Central  Google Scholar 

Carolina E, et al. Glucocorticoid impaired the wound healing ability of endothelial progenitor cells by reducing the expression of CXCR4 in the PGE2 pathway. Front Med. 2018;28:5:276. https://doi.org/10.3389/fmed.2018.00276

Rodrigues M, Kosaric N, Bonham CA, Gurtner GC. Wound healing: a cellular perspective. Physiol Rev. 2019;99(1):665–706. https://doi.org/10.1152/physrev.00067.2017.

Article  CAS  PubMed  Google Scholar 

Silva JR, Burger B, Kühl CMC, Candreva T, dos Anjos MBP, Rodrigues HG. Wound healing and omega-6 fatty acids: from inflammation to repair. Mediators Inflamm. 2018;2018:1. https://doi.org/10.1155/2018/2503950.

Article  CAS  Google Scholar 

Demidova-Rice TN, Hamblin MR, Herman IM. Acute and impaired wound healing: pathophysiology and current methods for drug delivery, Part 1: Normal and Chronic Wounds: Biology, Causes, and Approaches to Care. Adv Skin Wound Care. 2012;25(7):304–14. https://doi.org/10.1097/01.ASW.0000416006.55218.d0.

Article  PubMed  PubMed Central  Google Scholar 

Dreifke MB, Jayasuriya AA, Jayasuriya AC. Current wound healing procedures and potential care. Mater Sci Eng C Mater Biol Appl. 2015;48:651–62. https://doi.org/10.1016/j.msec.2014.12.068.

Article  CAS  PubMed  Google Scholar 

L. Li et al., “Quantitative assessment of angiogenesis in skin wound healing by multi-optical imaging techniques,” Front. Phys., vol. 10, 2022, Accessed: Aug. 11, 2023. [Online]. Available: https://www.frontiersin.org/articles/https://doi.org/10.3389/fphy.2022.894901

Negri S, Faris P, Berra-Romani R, Guerra G, Moccia F. Endothelial transient receptor potential channels and vascular remodeling: extracellular Ca2 + entry for angiogenesis, arteriogenesis and vasculogenesis. Front Physiol. 2019;10:1618. https://doi.org/10.3389/fphys.2019.01618.

Article  PubMed  Google Scholar 

Fallah A, et al. Therapeutic targeting of angiogenesis molecular pathways in angiogenesis-dependent diseases. Biomed Pharmacother. 2019;110:775–85. https://doi.org/10.1016/j.biopha.2018.12.022.

Article  CAS  PubMed  Google Scholar 

Qing C, “The molecular biology in wound healing & non-healing wound,” Chin. J. Traumatol. Zhonghua Chuang Shang Za Zhi. 2017; 20 (4), 189–193 https://doi.org/10.1016/j.cjtee.2017.06.001.

Rust R, Gantner C, Schwab ME. Pro- and antiangiogenic therapies: current status and clinical implications. FASEB J. 2019;33:34–48. https://doi.org/10.1096/fj.201800640RR.

“Biomimetics | Free Full-Text | The role of the extracellular matrix (ECM) in wound healing: a review.” Accessed: Mar. 13, 2024. [Online]. Available: https://www.mdpi.com/2313-7673/7/3/87

Adler M, et al. Principles of cell circuits for tissue repair and fibrosis. iScience. 2020;23(2):100841. https://doi.org/10.1016/j.isci.2020.100841.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moriyama M, et al. Beneficial effects of the genus aloe on wound healing, cell proliferation, and differentiation of epidermal keratinocytes. PLoS ONE. 2016;11(10):e0164799. https://doi.org/10.1371/journal.pone.0164799.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Belvedere R, Novizio N, Morello S, Petrella A. The combination of mesoglycan and VEGF promotes skin wound repair by enhancing the activation of endothelial cells and fibroblasts and their cross-talk. Sci Rep. 2022;12(1):1. https://doi.org/10.1038/s41598-022-15227-1.

Article  CAS  Google Scholar 

Zhao H, et al. Inflammation and tumor progression: signaling pathways and targeted intervention. Signal Transduct Target Ther. 2021;6(1):1. https://doi.org/10.1038/s41392-021-00658-5.

Article  CAS  Google Scholar 

Gainza G, Villullas S, Pedraz JL, Hernandez RM, Igartua M. Advances in drug delivery systems (DDSs) to release growth factors for wound healing and skin regeneration. Nanomedicine Nanotechnol Biol Med. 2015;11(6):1551–73. https://doi.org/10.1016/j.nano.2015.03.002.

Article  CAS  Google Scholar 

Park JW, Hwang SR, Yoon I-S. Advanced growth factor delivery systems in wound management and skin regeneration. Mol J Synth Chem Nat Prod Chem. 2017;22:8. https://doi.org/10.3390/molecules22081259.

Article  CAS  Google Scholar 

Öhnstedt E, Tomenius HL, Vågesjö E, Phillipson M. The discovery and development of topical medicines for wound healing. Expert Opin Drug Discov. 2019;14(5):485–97. https://doi.org/10.1080/17460441.2019.1588879.

Article  CAS  PubMed  Google Scholar 

Zhang T, et al. Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate keloid and hypertrophic scar formation. Biomed Pharmacother. 2020;129:110287. https://doi.org/10.1016/j.biopha.2020.110287.

Article  CAS  PubMed  Google Scholar 

Zheng S-Y, et al. Therapeutic role of growth factors in treating diabetic wound. World J Diabetes. 2023;14(4):364–95. https://doi.org/10.4239/wjd.v14.i4.364.

Article  PubMed  PubMed Central  Google Scholar 

Peng Y, et al. Comparative evaluation of the wound-healing potency of recombinant bFGF and ski gene therapy in rats. Growth Factors. 2016;34(3–4):119–27. https://doi.org/10.1080/08977194.2016.1200570.

Article  CAS  PubMed  Google Scholar 

Gilligan AM, Waycaster CR, Motley TA. Cost-effectiveness of becaplermin gel on wound healing of diabetic foot ulcers. Wound Repair Regen. 2015;23(3):353–60. https://doi.org/10.1111/wrr.12285.

Article  PubMed  Google Scholar 

Heyneman A, Hoeksema H, Vandekerckhove D, Pirayesh A, Monstrey S. The role of silver sulphadiazine in the conservative treatment of partial thickness burn wounds: a systematic review. Burns J Int Soc Burn Inj. 2016;42(7):1377–86. https://doi.org/10.1016/j.burns.2016.03.029.

Article  CAS  Google Scholar 

Dunn J, Liu Y, Banov F, Denison S, Banov D. A topical naltrexone formulation for surgical wound healing: a case report. J Cosmet Dermatol. 2020;20(3). https://doi.org/10.1111/jocd.13604.

McLaughlin PJ, Cain JD, Titunick MB, Sassani JW, Zagon IS. Topical naltrexone is a safe and effective alternative to standard treatment of diabetic wounds. Adv Wound Care. 2017;6(9):279–88. https://doi.org/10.1089/wound.2016.0725.

Article  Google Scholar 

Kogan S, Sood A, Garnick MS. Zinc and wound healing: a review of zinc physiology and clinical applications. Wounds Compend Clin Res Pract. 2017;29(4):102–6.

Google Scholar 

“Continuous electrical current and zinc sulphate administered by transdermal iontophoresis improves skin healing in diabetic rats induced by alloxan: morphological and ultrastructural analysis.” Accessed: Jan. 06, 2021. [Online]. Available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164307/

Adjepong D, Jahangir S, Malik BH, Dennis Adjepong MBA, Jahangir S, Malik BH. The effect of zinc on post-neurosurgical wound healing: a review. Cureus. 2020;12:1. https://doi.org/10.7759/cureus.6770.

Article  Google Scholar 

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