Comparison of anticoagulation control and outcomes between usual medical care and pharmacist-led anticoagulation service in ambulatory patients taking warfarin at tertiary hospital in Ethiopia: a quasi-experimental study

Sonuga BO, Hellenberg DA, Cupido CS, Jaeger C, Hospital V, Sonuga BO. Profile and anticoagulation outcomes of patients on warfarin therapy in an urban hospital in Cape Town, South Africa. African J Prim Heal care Fam Med. 2016;8(1):1–8.

Google Scholar 

Kearon C, Akl EA, Ornelas J, Blaivas A, Jimenez D, Bounameaux H, et al. Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report. Chest. 2016;149(2):315–52.

Article  PubMed  Google Scholar 

Tran NT, Lin CH, Do NN, Muradian IK, Lu QD, Henderson SO. The impact of implementing an advance practice pharmacist-led anticoagulation clinic within a correctional facility. J Pharm Pract. 2021;34(4):631–4.

Article  PubMed  Google Scholar 

Laäs DJ, Naidoo M. An evaluation of warfarin use at an urban district-level hospital in Kwazulu-natal Province, South Africa. S Afr Med J. 2018;108(12):1046–50.

Article  PubMed  Google Scholar 

Witt DM, Nieuwlaat R, Clark NP, Ansell J, Holbrook A, Skov J, et al. American society of hematology 2018 guidelines for management of venous thromboembolism: Optimal management of anticoagulation therapy. Blood Adv. 2018;2(22):3257–91.

Article  PubMed  PubMed Central  Google Scholar 

Zeitler EP, Eapen ZJ. Anticoagulation in Heart Failure: a Review. J Atr Fibrillation. 2015;8(1):1250.

Minno A Di, Frigerio B, Spadarella G, Sansaro D, Amato M, Kitzmiller JP, et al. Old and new oral anticoagulants: Food, herbal medicines and drug interactions. 2017. Available from: https://doi.org/10.1016/j.blre.2017.02.001.

Karuri S, Nyamu D, Opanga S, Menge T. Factors associated with time in therapeutic range among patients on oral anticoagulation therapy in a tertiary teaching and referral hospital in Kenya. East Cent African J Pharm Sci. 2019;22(3):85–95.

Google Scholar 

Alghadeeer S, Alzahrani AA, Alalayet WY, Alkharashi AA, Alarifi MN. Anticoagulation control of warfarin in pharmacist-led clinics versus physician-led clinics: A prospective observational study. Risk Manag Healthc Policy. 2020;13:1175–9.

Article  PubMed  PubMed Central  Google Scholar 

Mwita JC, Francis JM, Oyekunle AA, Gaenamong M, Goepamang M, Magafu MGMDMD. Quality of anticoagulation with warfarin at a tertiary hospital in Botswana. Clin Appl Thromb. 2018;24(4):596–601.

Article  Google Scholar 

Gabriel P, Barros M De, Sznejder H, Vasconcellos R, Charles GM, Tannus H, et al. Original Article anticoagulation therapy in patients with non-valvular atrial fibrillation in a private setting in Brazil : A Real ‑ World Study. 457–66.

Choumane NS, Malaeb DN, Malaeb B, Hallit S. A multicenter, prospective study evaluating the impact of the clinical pharmacist-physician counselling on warfarin therapy management in Lebanon. BMC Health Serv Res. 2018;18(1):1–7.

Article  Google Scholar 

Esteve-Pastor MA, Rivera-Caravaca JM, Roldán-Rabadán I, Roldán V, Muñiz J, Raña-Míguez P, et al. Quality of oral anticoagulation with Vitamin K antagonists in “real-world” patients with atrial fibrillation: A report from the prospective multicentre FANTASIIA registry. Europace. 2018;20(9):1435–41.

Article  PubMed  Google Scholar 

Turen S, Turen S. Determination of factors affecting time in therapeutic range in patients on warfarin therapy. Biol Res Nurs. 2023;25(1):170–8.

Article  CAS  PubMed  Google Scholar 

Ntlokotsi S, Moshesh MF, Mntla P, Towobola OA, Mogale MA. Optimum INR intensity and therapeutic INR control in patients with mechanical heart valve prosthesis on warfarin oral anticoagulation at Dr George Mukhari academic hospital: a three-year retrospective study. South African Fam Pract. 2018;60(6):192–6.

Article  Google Scholar 

Krittayaphong R, Chantrarat T, Rojjarekampai R, Jittham P. Poor time in therapeutic range control is associated with adverse clinical outcomes in patients with non-valvular atrial fibrillation : a report from the Nationwide COOL-AF Registry. J Clin Med. 2020;9(6):1–13.

Article  Google Scholar 

Vestergaard AS, Skj F, Larsen TB, Ehlers H. The importance of mean time in therapeutic range for complication rates in warfarin therapy of patients with atrial fibrillation : A systematic review and meta-regression analysis. 2017. p. 1–17.

Google Scholar 

Caldeira D, Cruz I, Morgado G, Stuart B, Gomes C, Martins C, et al. Evaluation of time in therapeutic range in anticoagulated patients: A single-center, retrospective, observational study. BMC Res Notes. 2014;7(1):1–5.

Article  Google Scholar 

Gateman D, Trojnar ME, Agarwal G, Gateman D, Trojnar ME, Agarwal G. Time in therapeutic range Un RIN dans la fourchette thérapeutique. Canadian Family Phys. 2017;63:425–31.

Google Scholar 

Chan P, Li WH, Hai J, Chan EW, Wong ICK, Tse H, et al. Time in therapeutic range and percentage of INRs in therapeutic range as measure of quality of anticoagulation control in atrial fibrillation patients. Can J Cardiol. 2015. Available from: https://doi.org/10.1016/j.cjca.2015.10.029

Farsad B, Abbasinazari M, Dabagh A, Bakshandeh H. Evaluation of Time in Therapeutic Range ( TTR ) in patients with non-valvular atrial fibrillation receiving treatment with warfarin in Tehran , Iran : A Cross-Sectional Study. 2016;20(9):20–2.

Han SY, Palmeri ST, Broderick SH, Hasselblad V, Rendall D, Stevens S, et al. Quality of anticoagulation with warfarin in patients with nonvalvular atrial fibrillation in the community setting. J Electrocardiol. 2013;46(1):45–50. https://doi.org/10.1016/j.jelectrocard.2012.08.011.

Article  PubMed  Google Scholar 

Botsile E, Mwita JC. Incidence and risk factors for thromboembolism and major bleeding in patients with mechanical heart valves: A tertiary hospital-based study in Botswana. Cardiovasc J Afr. 2020;31(4):185–9.

Article  PubMed  Google Scholar 

Jonkman LJ, Gwanyanya MP, Kakololo MN, Verbeeck RK, Singu BS. Assessment of anticoagulation management in outpatients attending a warfarin clinic in Windhoek, Namibia. Drugs Ther Perspect. 2019;35(7):341–6. https://doi.org/10.1007/s40267-019-00630-y.

Article  Google Scholar 

Ugur A, Turk O, Tuncer E, Alioglu E, Yuksel K. Evaluation of the impact of warfarin’s time-in-therapeutic range on outcomes of patients with atrial fibrillation in Turkey : Perspectives from the Observational , Prospective WATER Registry. 2015.

Google Scholar 

Quinn LM, Richardson R, Cameron KJ, Battistella M. Evaluating time in therapeutic range for hemodialysis patients taking warfarin. Clin Nephrol. 2015;83(2):80–5.

Article  CAS  PubMed  Google Scholar 

de Castro KP, Chiu HH, De Leon-Yao RC, Almelor-Sembrana L, Dans AM. A patient decision aid for anticoagulation therapy in patients with nonvalvular atrial fibrillation: development and pilot study. JMIR Cardio. 2021;5(2):e23464.

Article  PubMed  PubMed Central  Google Scholar 

Albabtain MA, Alharthi MM, Dagriri K, Arafat AA, Ayrout E, Alhebaishi Y, et al. Assessment of the quality of anticoagulation management with warfarin in a tertiary care center. Saudi Med J. 2020;41(11):1245–51.

Article  PubMed  PubMed Central  Google Scholar 

Ouali S, Ben Halima A, Chabrak S, Chettaoui R, Ben Halima A, Haggui A, et al. Epidemiological characteristics, management, and outcomes of atrial fibrillation in TUNISIA: Results from the National Tunisian Registry of Atrial Fibrillation (NATURE-AF). Clin Cardiol. 2021;44(4):501–10 Available from: NS -.

Article  PubMed  PubMed Central  Google Scholar 

Mariita K, Nyamu DG, Maina CK, Karimi PN. Patient factors impacting on oral anticoagulation therapy among adult outpatients in a Kenyan referral hospital. 2016.

Google Scholar 

Sadhabariss D, Brown SL. Warfarin: time in therapeutic range, a single centre study on patients using warfarin for stroke prevention in non-valvular atrial fibrillation and prosthetic heart valves. SA Hear. 2021;18(1):28–38.

Google Scholar 

Tadesse TA, Tegegne GT, Yadeta D, Chelkaba L, Fenta TG. Anticoagulation control, outcomes, and associated factors in long-term-care patients receiving warfarin in Africa: a systematic review. Thromb J. 2022;20(1):1–12 10.1186/s12959-022-00416-9. https://doi.org/10.1186/s12959-022-00416-9

Article  Google Scholar 

Fenta TG, Assefa T, Alemayehu B. Quality of anticoagulation management with warfarin among outpatients in a tertiary hospital in Addis Ababa, Ethiopia: a retrospective cross-sectional study. BMC Health Serv Res. 2017;17(1):1–7.

Article  Google Scholar 

Yimer NS, Abiye AA, Hussen SU, Tadesse TA. Anticoagulation control, outcomes, and associated factors in patients with atrial fibrillation receiving warfarin at tertiary care hospital in Ethiopia. Clin Appl Thromb. 2021;27:107602962110497.

Article  Google Scholar 

Liyew Z, Tadesse A, Bekele N, Tsegaye T. Evaluation of anticoagulation outcome among patients taking warfarin : a single-center experience , Northwest Ethiopia. Res Sq. 2017;20–5.

Masresha N, Muche EA, Atnafu A, Abdela O. Evaluation of warfarin anticoagulation at university of gondar comprehensive specialized hospital, north-west Ethiopia. J Blood Med. 2021;12:189–95.

Article  PubMed  PubMed Central  Google Scholar 

Getachew R, Tadesse TA, Shashu BA, Degu A, Alemkere G. Anticoagulation management in patients receiving warfarin at private cardiac centers in Addis Ababa. Ethiopia J Blood Med. 2023;14:107–17.

Article  CAS  PubMed  Google Scholar 

Teklay G, Shiferaw N, Legesse B, Bekele ML. Drug-drug interactions and risk of bleeding among inpatients on warfarin therapy : a prospective observational study. Thromb J. 2014;12(1):1–8.

Article  Google Scholar 

Tadesse TA, Woldu MA. Prevalence of warfarin drug interaction and warfarin education practice in outpatient setups of university teaching hospital. 2018. p. 262–6.

Google Scholar 

Bungard TJ, Gardner L, Archer SL, Hamilton P, Ritchie B, Tymchak W, et al. Evaluation of a pharmacist-managed anticoagulation clinic: Improving patient care. Open Med. 2009;3(1):16–21.

Google Scholar 

Tsuyuki RT, Bungard T, Grant CM, Ackman ML. Anticoagulation clinics in North America: Operational insights. Can J Hosp Pharm. 2008;61(4):245–6.

Google Scholar 

Hou K, Yang H, Ye Z, Wang Y, Liu L, Cui X. Effectiveness of pharmacist-led anticoagulation management on clinical outcomes : a systematic review and meta-analysis. J Pharm Pharm Sci. 2017;20(1):378–96.

Article  PubMed  Google Scholar 

Shah KJ, Pharm D, Mansukhani R, Pharm D, Bloomstein D, Pharm D, et al. Outcomes of a pharmacist managed anticoagulation service. J Oncol Pharm Pract. 2010;6:62–7.

留言 (0)

沒有登入
gif