Aguayo F, Perez-Dominguez F, Osorio JC, Oliva C, Calaf GM (2023) PI3K/AKT/mTOR signaling pathway in HPV-driven head and neck carcinogenesis: therapeutic implications. Biology 12(5):672. https://doi.org/10.3390/biology12050672

Article  CAS  PubMed  PubMed Central  Google Scholar 

Akagi K, Li J, Broutian TR, Padilla-Nash H, Xiao W, Jiang B, Rocco JW et al (2014) Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res 24(2):185–99. https://doi.org/10.1101/gr.164806.113

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SAJR, Behjati S, Biankin AV, Bignell GR et al (2013) Signatures of mutational processes in human cancer. Nature 500(7463):415–21. https://doi.org/10.1038/nature12477

Article  CAS  PubMed  PubMed Central  Google Scholar 

Argyris PP, Wilkinson PE, Jarvis MC, Magliocca KR, Patel MR, Vogel RI, Gopalakrishnan R, Koutlas IG, Harris RS (2021) Endogenous APOBEC3B overexpression characterizes HPV-positive and HPV-negative oral epithelial dysplasias and head and neck cancers. Mod Pathol Off J U S Can Acad Pathol Inc 34(2):280–90. https://doi.org/10.1038/s41379-020-0617-x

Article  CAS  Google Scholar 

Bello JOM, Nieva LO, Paredes AC, Gonzalez AMF, Zavaleta LR, Lizano M (2015) Regulation of the Wnt/β-catenin signaling pathway by human papillomavirus E6 and E7 oncoproteins. Viruses 7(8):4734–55. https://doi.org/10.3390/v7082842

Article  CAS  PubMed  Google Scholar 

Boshart M, Gissmann L, Ikenberg H, Kleinheinz A, Scheurlen W, zur Hausen H (1984) A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer. EMBO J 3(5):1151–57. https://doi.org/10.1002/j.1460-2075.1984.tb01944.x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bürckstümmer T, Baumann C, Blüml S, Dixit E, Dürnberger G, Jahn H, Planyavsky M et al (2009) An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 10(3):266–72. https://doi.org/10.1038/ni.1702

Article  CAS  PubMed  Google Scholar 

Burd EM (2003) Human papillomavirus and cervical cancer. Clin Microbiol Rev 16(1):1–17. https://doi.org/10.1128/CMR.16.1.1-17.2003

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cai X, Li G, Laimins LA, Cullen BR (2006) Human papillomavirus genotype 31 does not express detectable microRNA levels during latent or productive virus replication. J Virol 80(21):10890–93. https://doi.org/10.1128/JVI.01175-06

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cancer Genome Atlas Research Network, Albert Einstein College of Medicine, Analytical Biological Services, Barretos Cancer Hospital, Baylor College of Medicine, Beckman Research Institute of City of Hope, Buck Institute for Research on Aging et al (2017) Integrated genomic and molecular characterization of cervical cancer. Nature 543(7645):378–84. https://doi.org/10.1038/nature21386

Article  CAS  Google Scholar 

Chen L, Qiu X, Zhang N, Wang Y, Wang M, Li D, Wang L, Du Y (2017) APOBEC-mediated genomic alterations link immunity and viral infection during human papillomavirus-driven cervical carcinogenesis. Biosci Trends 11(4):383–88. https://doi.org/10.5582/bst.2017.01103

Article  CAS  PubMed  Google Scholar 

Chirayil R, Kincaid RP, Dahlke C, Kuny CV, Dälken N, Spohn M, Lawson B, Grundhoff A, Sullivan CS (2018) Identification of virus-encoded microRNAs in divergent papillomaviruses. PLoS Pathog 14(7):e1007156. https://doi.org/10.1371/journal.ppat.1007156

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chiu Y-H, Macmillan JB, Chen ZJ (2009) RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 138(3):576–91. https://doi.org/10.1016/j.cell.2009.06.015

Article  CAS  PubMed  PubMed Central  Google Scholar 

Clifford GM, Smith JS, Plummer M, Muñoz N, Franceschi S (2003) Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis. Br J Cancer 88(1):63–73. https://doi.org/10.1038/sj.bjc.6600688

Article  CAS  PubMed  PubMed Central  Google Scholar 

Das T, Zhong R, Spiotto MT (2021) Notch signaling and human papillomavirus-associated oral tumorigenesis. Adv Exp Med Biol 1287:105–22. https://doi.org/10.1007/978-3-030-55031-8_8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dass D, Dhotre K, Chakraborty M, Nath A, Banerjee A, Bagchi P, Mukherjee A (2023) miRNAs in herpesvirus infection: powerful regulators in small packages. Viruses 15(2):429. https://doi.org/10.3390/v15020429

Article  CAS  PubMed  PubMed Central  Google Scholar 

de Freitas AC, de Oliveira THA, Barros MR, Venuti A (2017) hrHPV E5 oncoprotein: immune evasion and related immunotherapies. J Exp Clin Cancer Res: CR 36(1):71. https://doi.org/10.1186/s13046-017-0541-1

Article  CAS  PubMed  PubMed Central  Google Scholar 

de Martel C, Georges D, Bray F, Ferlay J, Clifford GM (2020) Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis. Lancet Glob Health 8(2):e180-90. https://doi.org/10.1016/S2214-109X(19)30488-7

Article  PubMed  Google Scholar 

Dürst M, Gissmann L, Ikenberg H, zur Hausen H (1983) A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions. Proc Natl Acad Sci USA 80(12):3812–15. https://doi.org/10.1073/pnas.80.12.3812

Article  PubMed  PubMed Central  Google Scholar 

Faden DL, Kuhs KAL, Lin M, Langenbucher A, Pinheiro M, Yeager M, Cullen M et al (2021) APOBEC mutagenesis is concordant between tumor and viral genomes in HPV-positive head and neck squamous cell carcinoma. Viruses 13(8):1666. https://doi.org/10.3390/v13081666

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fischer M (2017) Census and evaluation of P53 target genes. Oncogene 36(28):3943–3956. https://doi.org/10.1038/onc.2016.502

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gallo A, Miceli V, Bulati M, Iannolo G, Contino F, Conaldi PG (2020) Viral miRNAs as active players and participants in tumorigenesis. Cancers 12(2):358. https://doi.org/10.3390/cancers12020358

Article  CAS  PubMed  PubMed Central  Google Scholar 

Galloway DA, Laimins LA (2015) Human papillomaviruses: shared and distinct pathways for pathogenesis. Curr Opin Virol 14(październik):87–92. https://doi.org/10.1016/j.coviro.2015.09.001

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gardiol D, Kühne C, Glaunsinger B, Lee SS, Javier R, Banks L (1999) Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation. Oncogene 18(40):5487–96. https://doi.org/10.1038/sj.onc.1202920

Article  CAS  PubMed  Google Scholar 

Ghoreshi Z-A-S (2023) The role of DNA viruses in human cancer. Cancer Inform 22:11769351231154186. https://doi.org/10.1177/11769351231154186

Article  PubMed  PubMed Central  Google Scholar 

Ghoreshi Z-A, Nakhaee M, Samie M, Zak MS, Arefini N (2022) Innate immune sensors for detecting nucleic acids during infection. J Lab Med. https://doi.org/10.1515/labmed-2021-0173

Article