Yoshida Y, Simoes EJ. Sugar-Sweetened Beverage, Obesity, and Type 2 Diabetes in Children and Adolescents: Policies, Taxation, and Programs. Curr Diab Rep. 2018;18:31.
Article PubMed PubMed Central Google Scholar
Reinehr T, Wabitsch M. Childhood obesity. Curr Opin Lipidol. 2011;22:21–5.
Article CAS PubMed Google Scholar
Hassapidou M, Tzotzas T, Makri E, Pagkalos I, Kaklamanos I, Kapantais E, et al. Prevalence and geographic variation of abdominal obesity in 7- and 9-year-old children in Greece; World Health Organization Childhood Obesity Surveillance Initiative 2010. BMC Public Health. 2017;17:126.
Article PubMed PubMed Central Google Scholar
Chen S, Binns CW, Zhang Y. The importance of definition in diagnosing obesity: a review of studies of children in China. Asia Pac J Public Health. 2012;24:248–62.
Kinlen D, Cody D, O’Shea D. Complications of obesity. QJM. 2018;111:437–43.
Article CAS PubMed Google Scholar
Sies H. Oxidative stress: a concept in redox biology and medicine. Redox Biol. 2015;4:180–3.
Article CAS PubMed PubMed Central Google Scholar
Keaney JF Jr, Larson MG, Vasan RS, Wilson PW, Lipinska I, Corey D, et al. Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol. 2003;23:434–9.
Article CAS PubMed Google Scholar
Strauss RS. Comparison of serum concentrations of alpha-tocopherol and beta-carotene in a cross-sectional sample of obese and nonobese children (NHANES III). National Health and Nutrition Examination Survey. J Pediatr. 1999;134:160–5.
Article CAS PubMed Google Scholar
Pérez-Torres I, Castrejón-Tellez V, Soto ME, Rubio-Ruiz ME, Manzano-Pech L, Guarner-Lans V. Oxidative stress, plant natural antioxidants, and obesity. Int J Mol Sci. 2021;22(4):1786.
Scott LJ. Sitagliptin: A Review in Type 2 Diabetes. Drugs. 2017;77:209–24.
Article CAS PubMed Google Scholar
Barnett A. DPP-4 inhibitors and their potential role in the management of type 2 diabetes. Int J Clin Pract. 2006;60:1454–70.
Article CAS PubMed Google Scholar
Ji Y, Nyamagoud SB, SreeHarsha N, Mishra A, Gubbiyappa SK, Singh Y. Sitagliptin protects liver against aflatoxin B1-induced hepatotoxicity through upregulating Nrf2/ARE/HO-1 pathway. BioFactors. 2020;46:76–82.
Article CAS PubMed Google Scholar
Chan J, Telang R, Kociszewska D, Thorne PR, Vlajkovic SM. A high-fat diet induces low-grade cochlear inflammation in CD-1 mice. Int J Mol Sci 2022;23(9):5179.
Brestoff JR, Artis D. Immune regulation of metabolic homeostasis in health and disease. Cell. 2015;161:146–60.
Article CAS PubMed PubMed Central Google Scholar
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259:87–91.
Article CAS PubMed Google Scholar
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003;112:1821–30.
Article CAS PubMed PubMed Central Google Scholar
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112:1796–808.
Article CAS PubMed PubMed Central Google Scholar
Engin A. The Pathogenesis of Obesity-Associated Adipose Tissue Inflammation. Adv Exp Med Biol. 2017;960:221–45.
Article CAS PubMed Google Scholar
Wang Y, Tang B, Long L, Luo P, Xiang W, Li X, et al. Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages. Nat Commun. 2021;12:102.
Article CAS PubMed PubMed Central Google Scholar
Kania DS, Gonzalvo JD, Weber ZA. Saxagliptin: a clinical review in the treatment of type 2 diabetes mellitus. Clin Ther. 2011;33:1005–22.
Article CAS PubMed Google Scholar
Shan B, Wang X, Wu Y, Xu C, Xia Z, Dai J, et al. The metabolic ER stress sensor IRE1alpha suppresses alternative activation of macrophages and impairs energy expenditure in obesity. Nat Immunol. 2017;18:519–29.
Article CAS PubMed Google Scholar
Kawanishi N, Yano H, Yokogawa Y, Suzuki K. Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice. Exerc Immunol Rev. 2010;16:105–18.
Shin S, Wakabayashi J, Yates MS, Wakabayashi N, Dolan PM, Aja S, et al. Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide. Eur J Pharmacol. 2009;620:138–44.
Article CAS PubMed PubMed Central Google Scholar
Yu Z, Shao W, Chiang Y, Foltz W, Zhang Z, Ling W, et al. Oltipraz upregulates the nuclear factor (erythroid-derived 2)-like 2 [corrected](NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice. Diabetologia. 2011;54:922–34.
Article CAS PubMed Google Scholar
Nagata N, Xu L, Kohno S, Ushida Y, Aoki Y, Umeda R, et al. Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice. Diabetes. 2017;66:1222–36.
Article CAS PubMed Google Scholar
Tarantini S, Valcarcel-Ares MN, Yabluchanskiy A, Tucsek Z, Hertelendy P, Kiss T, et al. Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype. J Gerontol A Biol Sci Med Sci. 2018;73:853–63.
Article CAS PubMed Google Scholar
A JIR, Uddandrao VVS, G S, G S, P C, S S, et al. Biochanin A attenuates obesity cardiomyopathy in rats by inhibiting oxidative stress and inflammation through the Nrf-2 pathway. Arch Physiol Biochem 2021;129(3):788–798. https://doi.org/10.1080/13813455.2021.1874017.
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