Vollmer TL, Nair KV, Williams IM, Alvarez E. Multiple sclerosis phenotypes as a Continuum: the role of neurologic Reserve. Neurol Clin Pract. 2021;11(4):342–51.
Article PubMed PubMed Central Google Scholar
Kuhlmann T, Moccia M, Coetzee T, Cohen JA, Correale J, Graves J, et al. Multiple sclerosis progression: time for a new mechanism-driven framework. Lancet Neurol. 2023;22(1):78–88.
Lucchinetti C, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol. 2000;47(6):707–17.
Article CAS PubMed Google Scholar
Khalil M, Teunissen CE, Otto M, Piehl F, Sormani MP, Gattringer T, et al. Neurofilaments as biomarkers in neurological disorders. Nat Rev Neurol. 2018;14(10):577–89.
Article CAS PubMed Google Scholar
Barro C, Benkert P, Disanto G, Tsagkas C, Amann M, Naegelin Y, et al. Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis. Brain. 2018;141(8):2382–91.
Kuhle J, Kropshofer H, Haering DA, Kundu U, Meinert R, Barro C, et al. Blood neurofilament light chain as a biomarker of MS disease activity and treatment response. Neurology. 2019;92(10):e1007–15.
Article CAS PubMed PubMed Central Google Scholar
Benkert P, Meier S, Schaedelin S, Manouchehrinia A, Yaldizli Ö, Maceski A, et al. Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study. Lancet Neurol. 2022;21(3):246–57.
Mouton-Barbosa E, Roux-Dalvai F, Bouyssié D, Berger F, Schmidt E, Righetti PG, et al. In-depth exploration of cerebrospinal fluid by combining peptide ligand library treatment and label-free protein quantification. Mol Cell Proteom. 2010;9(5):1006–21.
Reiber H. Dynamics of brain-derived proteins in cerebrospinal fluid. Clin Chim Acta. 2001;310(2):173–86.
Article CAS PubMed Google Scholar
Begcevic I, Brinc D, Drabovich AP, Batruch I, Diamandis EP. Identification of brain-enriched proteins in the cerebrospinal fluid proteome by LC-MS/MS profiling and mining of the human protein atlas. Clin Proteom. 2016;13(1):11.
Begcevic I, Brinc D, Dukic L, Simundic AM, Zavoreo I, Basic Kes V, et al. Targeted Mass Spectrometry-based assays for relative quantification of 30 brain-related proteins and their clinical applications. J Proteome Res. 2018;17(7):2282–92.
Article CAS PubMed Google Scholar
Batruch I, Lim B, Soosaipillai A, Brinc D, Fiala C, Diamandis EP. Mass Spectrometry-based assay for Targeting fifty-two proteins of Brain Origin in Cerebrospinal Fluid. J Proteome Res. 2020;19(8):3060–71.
Article CAS PubMed Google Scholar
Sohaei D, Thebault S, Avery LM, Batruch I, Lam B, Xu W, et al. Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis. Clin Proteom. 2023;20(1):33.
R Core Team. (2022). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. URL https://www.R-project.org/.
R-PLEX human neurofilament light datasheet [Internet]. 2022. https://www.mesoscale.com/%7E/media/files/data%20sheets/ds-r-plex-human-neurofilament-l.pdf [Accessed 3 Mar 2024].
Binder JX, Pletscher-Frankild S, Tsafou K, Stolte C, O’Donoghue SI, Schneider R et al. COMPARTMENTS: unification and visualization of protein subcellular localization evidence. Database. 2014;2014.
Szklarczyk D, Gable AL, Lyon D, Junge A, Wyder S, Huerta-Cepas J, et al. STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets. Nucleic Acids Res. 2019;47(D1):D607–13.
Article CAS PubMed Google Scholar
Ebers GC. Natural history of primary progressive multiple sclerosis. Mult Scler. 2004;10(Suppl 1):S8–13. discussion S-5.
Kister I, Chamot E, Salter AR, Cutter GR, Bacon TE, Herbert J. Disability in multiple sclerosis: a reference for patients and clinicians. Neurology. 2013;80(11):1018–24.
Article PubMed PubMed Central Google Scholar
Novakova L, Zetterberg H, Sundström P, Axelsson M, Khademi M, Gunnarsson M, et al. Monitoring disease activity in multiple sclerosis using serum neurofilament light protein. Neurology. 2017;89(22):2230–7.
Article CAS PubMed PubMed Central Google Scholar
Zhang Y, Sloan Steven A, Clarke Laura E, Caneda C, Plaza Colton A, Blumenthal Paul D, et al. Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with Mouse. Neuron. 2016;89(1):37–53.
Article CAS PubMed Google Scholar
Axelsson M, Malmeström C, Nilsson S, Haghighi S, Rosengren L, Lycke J. Glial fibrillary acidic protein: a potential biomarker for progression in multiple sclerosis. J Neurol. 2011;258(5):882–8.
Article CAS PubMed Google Scholar
Stoop MP, Runia TF, Stingl C, van der Vuurst RM, Luider TM, Hintzen RQ. Decreased neuro-axonal proteins in CSF at First Attack of suspected multiple sclerosis. Proteom Clin Appl. 2017;11:11–2.
Mosleth EF, Vedeler CA, Liland KH, McLeod A, Bringeland GH, Kroondijk L, et al. Cerebrospinal fluid proteome shows disrupted neuronal development in multiple sclerosis. Sci Rep. 2021;11(1):4087.
Article CAS PubMed PubMed Central Google Scholar
Kroksveen AC, Aasebø E, Vethe H, Van Pesch V, Franciotta D, Teunissen CE, et al. Discovery and initial verification of differentially abundant proteins between multiple sclerosis patients and controls using iTRAQ and SID-SRM. J Proteom. 2013;78:312–25.
Schutzer SE, Angel TE, Liu T, Schepmoes AA, Xie F, Bergquist J, et al. Gray matter is targeted in first-attack multiple sclerosis. PLoS ONE. 2013;8(9):e66117.
Article CAS PubMed PubMed Central Google Scholar
Dhaunchak AS, Becker C, Schulman H, De Faria O Jr., Rajasekharan S, Banwell B, et al. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Ann Neurol. 2012;71(5):601–13.
Abdi F, Quinn JF, Jankovic J, McIntosh M, Leverenz JB, Peskind E, et al. Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J Alzheimers Dis. 2006;9(3):293–348.
Article CAS PubMed Google Scholar
Fang Q, Strand A, Law W, Faca VM, Fitzgibbon MP, Hamel N, et al. Brain-specific proteins decline in the cerebrospinal fluid of humans with Huntington disease. Mol Cell Proteom. 2009;8(3):451–66.
Mapstone M, Cheema AK, Fiandaca MS, Zhong X, Mhyre TR, MacArthur LH, et al. Plasma phospholipids identify antecedent memory impairment in older adults. Nat Med. 2014;20(4):415–8.
Article CAS PubMed Google Scholar
Wassif WS, Sherwood RA, Amir A, Idowu B, Summers B, Leigh N, et al. Serum carnosinase activities in central nervous system disorders. Clin Chim Acta. 1994;225(1):57–64.
Article CAS PubMed Google Scholar
Borràs E, Cantó E, Choi M, Maria Villar L, Álvarez-Cermeño JC, Chiva C, et al. Protein-based classifier to Predict Conversion from clinically isolated syndrome to multiple Sclerosis*. Mol Cell Proteom. 2016;15(1):318–28.
Cantó E, Tintoré M, Villar LM, Borrás E, Álvarez-Cermeño JC, Chiva C, et al. Validation of semaphorin 7A and ala-β-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis. J Neuroinflamm. 2014;11(1):181.
Bellia F, Vecchio G, Rizzarelli E. Carnosinases, their substrates and diseases. Molecules. 2014;19(2):2299–329.
留言 (0)