Aktuelle Forschungsergebnisse zur Neuropsychologie dissoziativer Anfälle

Williams IA, Levita L, Reuber M (2018) Emotion dysregulation in patients with psychogenic nonepileptic seizures: a systematic review based on the extended process model. Epilepsy Behav 86:37–48

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Jungilligens J, Wellmer J, Schlegel U et al (2020) Impaired emotional and behavioural awareness and control in patients with dissociative seizures. Psychol Med 50:2731–2739

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Pick S, Mellers JD, Goldstein LH (2016) Explicit facial emotion processing in patients with dissociative seizures. Psychosom Med 78:874–885

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Bakvis P, Spinhoven P, Zitman FG, Roelofs K (2011) Automatic avoidance tendencies in patients with psychogenic non-epileptic seizures. Seizure 20:628–634

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Jungilligens J, Wellmer J, Kowoll A et al (2021) Microstructural integrity of affective neurocircuitry in patients with dissociative seizures is associated with emotional task performance, illness severity and trauma history. Seizure 84:91–98

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Jungilligens J, Flohr MC, Lange M et al (2023) The relationship of action, affect, and metacognition in functional seizures. J Clin Exp Neuropsychol. https://doi.org/10.1080/13803395.2023.2287778

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Millman LSM, Short E, Stanton B et al (2023) Interoception in functional motor symptoms and functional seizures: preliminary evidence of intact accuracy alongside reduced insight and altered sensibility. Behav Res Ther 168:104379

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Koreki A, Garfkinel SN, Mula M et al (2020) Trait and state interoceptive abnormalities are associated with dissociation and seizure frequency in patients with functional seizures. Epilepsia 61:1156–1165

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Pick S, Rojas-Aguiluz M, Butler M et al (2020) Dissociation and interoception in functional neurological disorder. Cogn Neuropsychiatry 25:294–311

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Cassady M, Baslet G (2023) Dissociation in patients with epilepsy and functional seizures: a narrative review of the literature. Seizure 110:220–230

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Roydeva MI, Reinders A (2021) Biomarkers of pathological dissociation: a systematic review. Neurosci Biobehav Rev 123:120–202

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Flasbeck V, Jungilligens J, Lemke I et al (2024) Heartbeat evoked potentials and autonomic arousal during dissociative seizures – insights from electrophysiology and neuroimaging. BMJ Neurol Open (in press)

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Elkommos S, Martin-Lopez D, Koreki A et al (2023) Changes in the heartbeat-evoked potential are associated with functional seizures. J Neurol Neurosurg Psychiatry 94:769–775

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Voon V, Brezing C, Gallea C et al (2010) Emotional stimuli and motor conversion disorder. Brain 133:1526–1536

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Aybek S, Nicholson TR, O’daly O et al (2015) Emotion-motion interactions in conversion disorder: an FMRI study. PLoS ONE 10:e123273

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Li R, Li Y, An D et al (2015) Altered regional activity and inter-regional functional connectivity in psychogenic non-epileptic seizures. Sci Rep 5:11635

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van der Kruijs SJ, Bodde NM, Vaessen MJ et al (2012) Functional connectivity of dissociation in patients with psychogenic non-epileptic seizures. J Neurol Neurosurg Psychiatry 83:239–247

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Zelinski L, Diez I, Perez DL et al (2022) Cortical thickness in default mode network hubs correlates with clinical features of dissociative seizures. Epilepsy Behav 128:108605

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Diez I, Larson AG, Nakhate V et al (2021) Early-life trauma endophenotypes and brain circuit-gene expression relationships in functional neurological (conversion) disorder. Mol Psychiatry 26:3817–3828

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Spagnolo PA, Norato G, Maurer CW et al (2020) Effects of TPH2 gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders. J Neurol Neurosurg Psychiatry 91:814–821

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Perez DL, Matin N, Barsky A et al (2017) Cingulo-insular structural alterations associated with psychogenic symptoms, childhood abuse and PTSD in functional neurological disorders. J Neurol Neurosurg Psychiatry 88:491–497

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Jungilligens J, Popkirov S, Perez DL, Diez I (2022) Linking gene expression patterns and brain morphometry to trauma and symptom severity in patients with functional seizures. Psychiatry Res Neuroimaging 326:111533

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Villagran A, Eldoen G, Duncan R et al (2021) Incidence and prevalence of psychogenic nonepileptic seizures in a Norwegian county: a 10-year population-based study. Epilepsia 62:1528–1535

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Operto FF, Coppola G, Mazza R et al (2019) Psychogenic nonepileptic seizures in pediatric population: a review. Brain Behav 9:e1406

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Dhiman V, Sinha S, Rawat VS et al (2014) Children with psychogenic non-epileptic seizures (PNES): a detailed semiologic analysis and modified new classification. Brain Dev 36:287–293

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Madaan P, Gulati S, Chakrabarty B et al (2018) Clinical spectrum of psychogenic non epileptic seizures in children; an observational study. Seizure 59:60–66

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Reilly C, Jette N, Johnson EC et al (2023) Scoping review and expert-based consensus recommendations for assessment and management of psychogenic non-epileptic (functional) seizures (PNES) in children: a report from the pediatric psychiatric issues task force of the international league against epilepsy. Epilepsia. https://doi.org/10.1111/epi.17768

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Jungilligens J, Paredes-Echeverri S, Popkirov S et al (2022) A new science of emotion: implications for functional neurological disorder. Brain 145:2648–2663

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Kozlowska K, Chudleigh C, Cruz C et al (2018) Psychogenic non-epileptic seizures in children and adolescents: part II—explanations to families, treatment, and group outcomes. Clin Child Psychol Psychiatry 23:160–176

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Gaskell C, Power N, Novakova B et al (2023) A meta-analytic review of the effectiveness of psychological treatment of functional/dissociative seizures on non-seizure outcomes in adults. Epilepsia. https://doi.org/10.1111/epi.17626

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Verrel J, Chwolka F, Filevich E et al (2023) Impaired Metacognition of voluntary movement in functional movement disorder. Mov Disord 38:435–443

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Senf-Beckenbach P, Hoheisel M, Devine J et al (2022) Evaluation of a new body-focused group therapy versus a guided self-help group program for adults with psychogenic non-epileptic seizures (PNES): a pilot randomized controlled feasibility study. J Neurol 269:427–436

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