Cystatin C and the misdiagnosis of CKD in older adults

Eriksen, B. O. et al. GFR in healthy aging: an individual participant data meta-analysis of iohexol clearance in European population-based cohorts. J. Am. Soc. Nephrol. 31, 1602–1615 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. 105, S117–S314 (2024).

Article  Google Scholar 

Liu, P. et al. Accounting for age in the definition of chronic kidney disease. JAMA Intern. Med. 181, 1359–1366 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Jonsson, A. J., Lund, S. H., Eriksen, B. O., Palsson, R. & Indridason, O. S. The prevalence of chronic kidney disease in Iceland according to KDIGO criteria and age-adapted estimated glomerular filtration rate thresholds. Kidney Int. 98, 1286–1295 (2020).

Article  CAS  PubMed  Google Scholar 

Kleeman, S. O. et al. Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy. Cell Genomics 3, 100347 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keddis, M. T. et al. GFR estimated with creatinine rather than cystatin C is more reflective of the true risk of adverse outcomes with low GFR in kidney transplant recipients. Nephrol. Dial. Transplant. 38, 1898–1906 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rule, A. D., Bailey, K. R., Lieske, J. C., Peyser, P. A. & Turner, S. T. Estimating the glomerular filtration rate from serum creatinine is better than from cystatin C for evaluating risk factors associated with chronic kidney disease. Kidney Int. 83, 1169–1176 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fu, E. L. et al. Association of low glomerular filtration rate with adverse outcomes at older age in a large population with routinely measured cystatin C. Ann. Intern. Med. 177, 269–279 (2024).

Article  PubMed  Google Scholar 

Asghar, M. S. et al. Age-based versus young-adult thresholds for nephrosclerosis on kidney biopsy and prognostic implications for CKD. J. Am. Soc. Nephrol. 34, 1421–1432 (2023).

Article  PubMed  Google Scholar 

Denic, A. et al. An improved method for estimating nephron number and the association of resulting nephron number estimates with chronic kidney disease outcomes. J. Am. Soc. Nephrol. 34, 1264–1278 (2023).

Article  PubMed  Google Scholar 

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