Prognostic Immunohistochemistry for Ki-67 and OTP on Small Biopsies of Pulmonary Carcinoid Tumors: Ki-67 Index Predicts Progression-free Survival and Atypical Histology

Departments of *Laboratory Medicine and Pathology

†Quantitative Health Sciences, Mayo Clinic Rochester, Rochester, MN

This project was funded by the Division of Anatomic Pathology, Mayo Clinic, Rochester, MN.

J.R.N.: identified samples, collected clinical data, scored immunohistochemistry, performed quality verification on automated scoring, helped obtain funding and drafted and edited the manuscript. S.M.J.: performed statistical analysis. A.C.R.: contributed to study conception and design, data collection, and manuscript revision. E.S.Y., Y.-C.L., M.C.B., J.J.M., and M.C.A.: study conception and design, and manuscript revision. J.M.B.: conceived of the project, obtained funding, supervised the project, scored immunohistochemistry, and edited the manuscript.

Conflicts of Interest and Source of Funding: The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article.

Correspondence: Jennifer M. Boland, MD, Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, 200 1st St SW Rochester MN 55902 (e-mail: [email protected]).

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