Ethics approval and consent to participate

The study was approved by local ethics committee (Comitato Etico Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UCSC; Approval Number, 28739/17) and all enrolled patients or next of kin provided written informed consent to participating in the study and data analysis.

Competing interests

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.