Higgins PD, Johanson JF (2004) Epidemiology of constipation in North America: a systematic review. Am J Gastroenterol 99(4):750–759. https://doi.org/10.1111/j.1572-0241.2004.04114.x

Article  PubMed  Google Scholar 

Mugie SM, Benninga MA, Di Lorenzo C (2011) Epidemiology of constipation in children and adults: a systematic review. Best Pract Res Clin Gastroenterol 25(1):3–18. https://doi.org/10.1016/j.bpg.2010.12.010

Article  PubMed  Google Scholar 

Abrahamsson H, Antov S, Bosaeus I (1988) Gastrointestinal and colonic segmental transit time evaluated by a single abdominal x-ray in healthy subjects and constipated patients. Scand J Gastroenterol Suppl 152:72–80. https://doi.org/10.3109/00365528809095938

Article  CAS  PubMed  Google Scholar 

Blake MR, Raker JM, Whelan K (2016) Validity and reliability of the Bristol Stool Form Scale in healthy adults and patients with diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther 44(7):693–703. https://doi.org/10.1111/apt.13746

Article  CAS  PubMed  Google Scholar 

Frank L, Kleinman L, Farup C, Taylor L, Miner P Jr (1999) Psychometric validation of a constipation symptom assessment questionnaire. Scand J Gastroenterol 34(9):870–877. https://doi.org/10.1080/003655299750025327

Article  CAS  PubMed  Google Scholar 

Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller R (2016) Bowel Disorders. Gastroenterology. https://doi.org/10.1053/j.gastro.2016.02.031

Emmanuel A, Cools M, Vandeplassche L, Kerstens R (2014) Prucalopride improves bowel function and colonic transit time in patients with chronic constipation: an integrated analysis. Am J Gastroenterol 109(6):887–894. https://doi.org/10.1038/ajg.2014.74

Article  CAS  PubMed  PubMed Central  Google Scholar 

Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC (2006) Functional bowel disorders. Gastroenterology 130(5):1480–1491. https://doi.org/10.1053/j.gastro.2005.11.061

Article  PubMed  Google Scholar 

Belsey J, Greenfield S, Candy D, Geraint M (2010) Systematic review: impact of constipation on quality of life in adults and children. Aliment Pharmacol Ther 31(9):938–949. https://doi.org/10.1111/j.1365-2036.2010.04273.x

Article  CAS  PubMed  Google Scholar 

Wald A, Scarpignato C, Kamm MA, Mueller-Lissner S, Helfrich I, Schuijt C, Bubeck J, Limoni C, Petrini O (2007) The burden of constipation on quality of life: results of a multinational survey. Aliment Pharmacol Ther 26(2):227–236. https://doi.org/10.1111/j.1365-2036.2007.03376.x

Article  CAS  PubMed  Google Scholar 

Quigley EM (2015) Probiotics in Irritable Bowel Syndrome: the Science and the evidence. J Clin Gastroenterol 49(Suppl 1):S60–64. https://doi.org/10.1097/mcg.0000000000000348

Article  CAS  PubMed  Google Scholar 

Applegate JA, Fischer Walker CL, Ambikapathi R, Black RE (2013) Systematic review of probiotics for the treatment of community-acquired acute diarrhea in children. BMC Public Health 13 Suppl 3 (Suppl 3):S16. https://doi.org/10.1186/1471-2458-13-s3-s16

Bernaola Aponte G, Bada Mancilla CA, Carreazo NY, Rojas Galarza RA (2013) Probiotics for treating persistent diarrhoea in children. Cochrane Database Syst Rev 2013 8(Cd007401). https://doi.org/10.1002/14651858.CD007401.pub3

Szajewska H, Canani RB, Guarino A, Hojsak I, Indrio F, Kolacek S, Orel R, Shamir R, Vandenplas Y, van Goudoever JB, Weizman Z (2016) Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Children. J Pediatr Gastroenterol Nutr 62(3):495–506. https://doi.org/10.1097/mpg.0000000000001081

Article  CAS  PubMed  Google Scholar 

Dimidi E, Mark Scott S, Whelan K (2020) Probiotics and constipation: mechanisms of action, evidence for effectiveness and utilisation by patients and healthcare professionals - ERRATUM. Proc Nutr Soc 79(1):170. https://doi.org/10.1017/s0029665119001058

Article  PubMed  Google Scholar 

Zhao Y, Yu YB (2016) Intestinal microbiota and chronic constipation. Springerplus 5(1):1130. https://doi.org/10.1186/s40064-016-2821-1

Article  PubMed  PubMed Central  Google Scholar 

Linetzky Waitzberg D, Alves Pereira CC, Logullo L, Manzoni Jacintho T, Almeida D, Teixeira da Silva ML, Matos de Miranda Torrinhas RS (2012) Microbiota benefits after inulin and partially hydrolized guar gum supplementation: a randomized clinical trial in constipated women. Nutr Hosp 27(1):123–129. https://doi.org/10.1590/s0212-16112012000100014

Article  CAS  PubMed  Google Scholar 

Bouhnik Y, Neut C, Raskine L, Michel C, Riottot M, Andrieux C, Guillemot F, Dyard F, Flourié B (2004) Prospective, randomized, parallel-group trial to evaluate the effects of lactulose and polyethylene glycol-4000 on colonic flora in chronic idiopathic constipation. Aliment Pharmacol Ther 19(8):889–899. https://doi.org/10.1111/j.1365-2036.2004.01918.x

Article  CAS  PubMed  Google Scholar 

Li T, Lu X, Yang X (2013) Stachyose-enriched α-galacto-oligosaccharides regulate gut microbiota and relieve constipation in mice. J Agric Food Chem 61(48):11825–11831. https://doi.org/10.1021/jf404160e

Article  CAS  PubMed  Google Scholar 

Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Moayyedi P (2014) Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. Am J Gastroenterol 109(10):1547–1561 quiz 1546, 1562. https://doi.org/10.1038/ajg.2014.202

Article  PubMed  Google Scholar 

Morelli L, Zonenschain D, Callegari ML, Grossi E, Maisano F, Fusillo M (2003) Assessment of a new synbiotic preparation in healthy volunteers: survival, persistence of probiotic strains and its effect on the indigenous flora. Nutr J 2:11. https://doi.org/10.1186/1475-2891-2-11

Article  PubMed  PubMed Central  Google Scholar 

Chmielewska A, Szajewska H (2010) Systematic review of randomised controlled trials: probiotics for functional constipation. World J Gastroenterol 16(1):69–75. https://doi.org/10.3748/wjg.v16.i1.69

Article  PubMed  PubMed Central  Google Scholar 

Dimidi E, Christodoulides S, Fragkos KC, Scott SM, Whelan K (2014) The effect of probiotics on functional constipation in adults: a systematic review and meta-analysis of randomized controlled trials. Am J Clin Nutr 100(4):1075–1084. https://doi.org/10.3945/ajcn.114.089151

Article  CAS  PubMed  Google Scholar 

Li Y, Cao L, Zhang Z, Hou L, Qin Y, Hui X, Li J, Zhao H, Cui G, Cui X, Li R, Lin Q, Li X, Yang K (2021) Reporting and methodological quality of COVID-19 systematic reviews needs to be improved: an evidence mapping. J Clin Epidemiol 135:17–28. https://doi.org/10.1016/j.jclinepi.2021.02.021

Article  PubMed  PubMed Central  Google Scholar 

Wang Y, Chen N, Guo K, Li Y, E F, Yang C, Shang X, Li X, Yang K (2023) Reporting and methodological quality of acupuncture network meta-analyses could be improved: an evidence mapping. J Clin Epidemiol 153:1–12. https://doi.org/10.1016/j.jclinepi.2022.11.004

Article  PubMed  Google Scholar 

Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (2022) Cochrane handbook for systematic reviews of interventions

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https://doi.org/10.1136/bmj.n71

Article  PubMed  PubMed Central  Google Scholar 

Whiting P, Savović J, Higgins JPT, Caldwell DM, Reeves BC, Shea B, Davies P, Kleijnen J, Churchill R (2018) [ROBIS: a new tool to assess risk of bias in systematic reviews was developed]. Recenti Prog Med 109(9):421–431. https://doi.org/10.1701/2990.29928

Article  PubMed  Google Scholar 

Luo S, Long Y, Xiao W, Wang X, Chen R, Guo Q, Liu J, Shao R, Du L, Chen M (2020) Risk of bias assessments and reporting quality of systematic reviews and randomized controlled trials examining acupuncture for depression: an overview and meta-epidemiology study. J Evid Based Med 13(1):25–33. https://doi.org/10.1111/jebm.12372

Article  PubMed  Google Scholar 

Hendarto A, Yosia M, Sastroasmoro S (2019) Quality analysis of randomized controlled trials reporting in the field of pediatrics by Indonesian researchers. J Evid Based Med 12(2):105–112. https://doi.org/10.1111/jebm.12328

Article  PubMed  Google Scholar 

Balduzzi S, Rücker G, Schwarzer G (2019) How to perform a meta-analysis with R: a practical tutorial. Evid Based Ment Health 22(4):153–160. https://doi.org/10.1136/ebmental-2019-300117

Article  PubMed  PubMed Central  Google Scholar 

Lin L, Zhang J, Hodges JS, Chu H (2017) Performing arm-based Network Meta-Analysis in R with the pcnetmeta Package. J Stat Softw 80. https://doi.org/10.18637/jss.v080.i05

Xu C, Niu Y, Wu J, Gu H, Zhang C (2018) Software and package applicating for network meta-analysis: a usage-based comparative study. J Evid Based Med 11(3):176–183. https://doi.org/10.1111/jebm.12264

Article  PubMed  Google Scholar 

Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327(7414):557–560. https://doi.org/10.1136/bmj.327.7414.557

Article  PubMed  PubMed Central  Google Scholar 

Salanti G, Ades AE, Ioannidis JP (2011) Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol 64(2):163–171. https://doi.org/10.1016/j.jclinepi.2010.03.016

Article  PubMed  Google Scholar 

Nikolakopoulou A, Higgins JPT, Papakonstantinou T, Chaimani A, Del Giovane C, Egger M, Salanti G (2020) CINeMA: an approach for assessing confidence in the results of a network meta-analysis. PLoS Med 17(4):e1003082. https://doi.org/10.1371/journal.pmed.1003082

Article  PubMed  PubMed Central  Google Scholar