Nieto, M. A., Huang, R. Y.-J., Jackson, R. A. & Thiery, J. P. EMT: 2016. Cell 166, 21–45 (2016).
Article CAS PubMed Google Scholar
Dongre, A. & Weinberg, R. A. New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer. Nat. Rev. Mol. Cell Biol. 20, 69–84 (2019).
Article CAS PubMed Google Scholar
Stone, R. C. et al. Epithelial–mesenchymal transition in tissue repair and fibrosis. Cell Tissue Res. 365, 495–506 (2016).
Article CAS PubMed PubMed Central Google Scholar
Yang, J. et al. Guidelines and definitions for research on epithelial–mesenchymal transition. Nat. Rev. Mol. Cell Biol. 21, 341–352 (2020).
Article PubMed PubMed Central Google Scholar
Pastushenko, I. & Blanpain, C. EMT transition states during tumor progression and metastasis. Trends Cell Biol. 29, 212–226 (2019).
Article CAS PubMed Google Scholar
Neumann, D. P., Goodall, G. J. & Gregory, P. A. Regulation of splicing and circularisation of RNA in epithelial mesenchymal plasticity. Semin. Cell Dev. Biol. 75, 50–60 (2018).
Article CAS PubMed Google Scholar
Skrypek, N., Goossens, S., De Smedt, E., Vandamme, N. & Berx, G. Epithelial-to-mesenchymal transition: epigenetic reprogramming driving cellular plasticity. Trends Genet. 33, 943–959 (2017).
Article CAS PubMed Google Scholar
Sample, R. A., Nogueira, M. F., Mitra, R. D. & Puram, S. V. Epigenetic regulation of hybrid epithelial–mesenchymal cell states in cancer. Oncogene 42, 2237–2248 (2023).
Article CAS PubMed PubMed Central Google Scholar
Morin, C., Moyret-Lalle, C., Mertani, H. C., Diaz, J.-J. & Marcel, V. Heterogeneity and dynamic of EMT through the plasticity of ribosome and mRNA translation. Biochim. Biophys. Acta Rev. Cancer 1877, 188718 (2022).
Article CAS PubMed Google Scholar
Cano, A. et al. The transcription factor snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2, 76–83 (2000).
Article CAS PubMed Google Scholar
Batlle, E. et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2, 84–89 (2000).
Article CAS PubMed Google Scholar
Stanisavljevic, J., Porta-de-la-Riva, M., Batlle, R., de Herreros, A. G. & Baulida, J. The p65 subunit of NF-κB and PARP1 assist Snail1 in activating fibronectin transcription. J. Cell Sci. 124, 4161–4171 (2011).
Article CAS PubMed Google Scholar
Hsu, D. S.-S. et al. Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages. Cancer Cell 26, 534–548 (2014).
Article CAS PubMed Google Scholar
Aghdassi, A. et al. Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer. Gut 61, 439–448 (2012).
Article CAS PubMed Google Scholar
Lehmann, W. et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat. Commun. 7, 10498 (2016).
Article CAS PubMed PubMed Central Google Scholar
Feldker, N. et al. Genome-wide cooperation of EMT transcription factor ZEB1 with YAP and AP-1 in breast cancer. EMBO J. 39, e103209 (2020).
Article CAS PubMed PubMed Central Google Scholar
Leptin, M. twist and snail as positive and negative regulators during Drosophila mesoderm development. Genes Dev. 5, 1568–1576 (1991).
Article CAS PubMed Google Scholar
Chen, Z. F. & Behringer, R. R. twist is required in head mesenchyme for cranial neural tube morphogenesis. Genes Dev. 9, 686–699 (1995).
Article CAS PubMed Google Scholar
Ocaña, O. H. et al. Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell 22, 709–724 (2012).
Yeo, S.-Y. et al. A positive feedback loop bi-stably activates fibroblasts. Nat. Commun. 9, 3016 (2018).
Article PubMed PubMed Central Google Scholar
Nieto, M. A. Epithelial plasticity: a common theme in embryonic and cancer cells. Science 342, 1234850 (2013).
Probst, S. et al. Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Development 148, dev193789 (2021).
Article CAS PubMed Google Scholar
Burtscher, I. & Lickert, H. Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo. Development 136, 1029–1038 (2009).
Article CAS PubMed Google Scholar
Nowotschin, S., Hadjantonakis, A.-K. & Campbell, K. The endoderm: a divergent cell lineage with many commonalities. Development 146, dev150920 (2019).
Article CAS PubMed PubMed Central Google Scholar
Scheibner, K. et al. Epithelial cell plasticity drives endoderm formation during gastrulation. Nat. Cell Biol. 23, 692–703 (2021).
Article CAS PubMed PubMed Central Google Scholar
Jägle, S. et al. SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells. PLoS Genet. 13, e1007109 (2017).
Article PubMed PubMed Central Google Scholar
Piacentino, M. L., Li, Y. & Bronner, M. E. Epithelial-to-mesenchymal transition and different migration strategies as viewed from the neural crest. Curr. Opin. Cell Biol. 66, 43–50 (2020).
Article CAS PubMed PubMed Central Google Scholar
Li, Y. et al. In vivo quantitative imaging provides insights into trunk neural crest migration. Cell Rep. 26, 1489–1500.e3 (2019).
Article CAS PubMed PubMed Central Google Scholar
E Davies, J. et al. Epithelial-mesenchymal transition during extravillous trophoblast differentiation. Cell Adh. Migr. 10, 310–321 (2016).
Article PubMed PubMed Central Google Scholar
Turco, M. Y. & Moffett, A. Development of the human placenta. Development 146, dev163428 (2019).
Article CAS PubMed Google Scholar
DaSilva-Arnold, S., James, J. L., Al-Khan, A., Zamudio, S. & Illsley, N. P. Differentiation of first trimester cytotrophoblast to extravillous trophoblast involves an epithelial-mesenchymal transition. Placenta 36, 1412–1418 (2015).
Article CAS PubMed Google Scholar
Vento-Tormo, R. et al. Single-cell reconstruction of the early maternal-fetal interface in humans. Nature 563, 347–353 (2018).
Article CAS PubMed PubMed Central Google Scholar
Greenbaum, S. et al. A spatially resolved timeline of the human maternal–fetal interface. Nature 619, 595–605 (2023).
Article CAS PubMed PubMed Central Google Scholar
Kudo-Saito, C., Shirako, H., Takeuchi, T. & Kawakami, Y. Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells. Cancer Cell 15, 195–206 (2009).
Article CAS PubMed Google Scholar
Shibue, T. & Weinberg, R. A. EMT, CSCs, and drug resistance: the mechanistic link and clinical implications. Nat. Rev. Clin. Oncol. 14, 611–629 (2017).
Article PubMed PubMed Central Google Scholar
Du, L. et al. Mesenchymal-to-epithelial transition in the placental tissues of patients with preeclampsia. Hypertens. Res. 40, 67–72 (2017).
Article CAS PubMed Google Scholar
Harmon, A. C. et al. The role of inflammation in the pathology of preeclampsia. Clin. Sci. 130, 409–419 (2016).
留言 (0)