Recognition of nonself is necessary to activate Drosophila’s immune response against an insect parasite

Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell. 2010;140(6):805–20.

Article  CAS  PubMed  Google Scholar 

Turvey SE, Broide DH. Innate immunity. J Allergy Clin Immunol. 2010;125(2 Supplement 2):S24-32.

Article  PubMed  Google Scholar 

Medzhitov R, Janeway CA. Decoding the patterns of self and nonself by the innate immune system. Science. 2002;296(5566):298–300.

Article  CAS  PubMed  Google Scholar 

Mortimer NT, Fischer ML, Waring AL, Pooja KR, Kacsoh BZ, Brantley SE, et al. Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster. Proc Natl Acad Sci USA. 2021;118(39):1–12.

Article  Google Scholar 

Murgia C, Pritchard JK, Kim SY, Fassati A, Weiss RA. Clonal origin and evolution of a transmissible cancer. Cell. 2006;126(3):477–87.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hegenauer V, Fürst U, Kaiser B, Smoker M, Zipfel C, Felix G, et al. Detection of the plant parasite Cuscuta reflexa by a tomato cell surface receptor. Science. 2016;353(6298):478–81.

Article  CAS  PubMed  Google Scholar 

Hegenauer V, Slaby P, Körner M, Bruckmüller JA, Burggraf R, Albert I, et al. The tomato receptor CuRe1 senses a cell wall protein to identify Cuscuta as a pathogen. Nat Commun. 2020;11(1):5299.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zoccal KF, Bitencourt CDS, Paula-Silva FWG, Sorgi CA, De Castro Figueiredo Bordon K, Arantes EC, et al. TLR2, TLR4 and CD14 recognize venom-associated molecular patterns from Tityus serrulatus to induce macrophage-derived inflammatory mediators. PLoS ONE. 2014;9(2).

Article  PubMed  PubMed Central  Google Scholar 

Forbes AA, Bagley RK, Beer MA, Hippee AC, Widmayer HA. Quantifying the unquantifiable: why Hymenoptera, not Coleoptera, is the most speciose animal order. BMC Ecol. 2018;18(21):1–11.

Google Scholar 

Carton Y, Poirié M, Nappi AJ. Insect immune resistance to parasitoids. Insect Science. 2008;15(1):67–87.

Article  CAS  Google Scholar 

Reed DA, Luhring KA, Stafford CA, Hansen AK, Millar JG, Hanks LM, et al. Host defensive response against an egg parasitoid involves cellular encapsulation and melanization. Biol Control. 2007;41(2):214–22.

Article  Google Scholar 

Hu J, Zhu XX, Fu WJ. Passive evasion of encapsulation in Macrocentrus cingulum Brischke (Hymenoptera: Braconidae), a polyembryonic parasitoid of Ostrinia furnacalis Guenée (Lepidoptera: Pyralidae). J Insect Physiol. 2003;49(4):367–75.

Article  CAS  PubMed  Google Scholar 

Dudzic JP, Kondo S, Ueda R, Bergman CM, Lemaitre B. Drosophila innate immunity: regional and functional specialization of prophenoloxidases. BMC Biol. 2015;13(1):81–97.

Article  PubMed  PubMed Central  Google Scholar 

Márkus R, Kurucz E, Rus F, Andó I. Sterile wounding is a minimal and sufficient trigger for a cellular immune response in Drosophila melanogaster. Immunol Lett. 2005;101(1):108–11.

Article  PubMed  Google Scholar 

Salt G. The cellular defence reactions of insects. Cambridge: Cambridge University Press; 1970.

G Salt FRS. Experimental studies in insect parasitism IX The reactions of a stick insect to an alien parasite. 1956;146:93–108.

Dubuffet A, Doury G, Labrousse C, Drezen JM, Carton Y, Marylène P. Variation of success of Leptopilina boulardi in Drosophila yakuba: the mechanisms explored. Dev Comp Immunol. 2008;32(February):597–602.

Article  PubMed  Google Scholar 

Cavigliasso F, Gatti JL, Colinet D, Poirié M. Impact of temperature on the immune interaction between a parasitoid wasp and drosophila host species. Insects. 2021;12(7):1–21.

Article  Google Scholar 

Moreau SJM, Eslin P, Giordanengo P, Doury G. Comparative study of the strategies evolved by two parasitoids of the genus Asobara to avoid the immune response of the host. Drosophila melanogaster Developmental and Comparative Immunology. 2003;27(4):273–82.

Article  CAS  PubMed  Google Scholar 

Kim MJ, Choe KM. Basement membrane and cell integrity of self-tissues in maintaining Drosophila immunological tolerance. PLoS Genetics. 2014;10(10):e1004683.

Article  PubMed  PubMed Central  Google Scholar 

Mortimer NT, Fischer ML, Waring AL, Pooja KR, Kacsoh BZ, Brantley SE, et al. Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster. Proc Natl Acad Sci USA. 2021;118(39):1–12.

Article  Google Scholar 

Ramond E, Dudzic JP, Lemaitre B. Comparative RNA-Seq analyses of Drosophila plasmatocytes reveal gene specific signatures in response to clean injury and septic injury. Bergmann A, editor. PLoS ONE. 2020;15(6):e0235294.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schlenke TA, Morales J, Govind S, Clark AG. Contrasting infection strategies in generalist and specialist wasp parasitoids of Drosophila melanogaster. PLoS pathogens. 2007;3(10):1486–501.

Article  PubMed  Google Scholar 

Tattikota SG, Cho B, Liu Y, Hu Y, Barrera V, Steinbaugh MJ, Yoon S-H, Comjean A, Li F, Dervis F et al: A singlecell survey of Drosophila blood. eLife. 2020;9:e54818.

Lemaitre B, Hoffmann J. The host defense of Drosophila melanogaster. Annu Rev Immunol. 2007;25(1):697–743.

Article  CAS  PubMed  Google Scholar 

Leitão AB, Arunkumar R, Day JP, Geldman EM, Morin-Poulard I, Crozatier M, et al. Constitutive activation of cellular immunity underlies the evolution of resistance to infection in Drosophila. eLife. 2020;9:e59095

Choi HW, Manohar M, Manosalva P, Tian M, Moreau M, Klessig DF. Activation of plant innate immunity by extracellular high mobility group box 3 and its inhibition by salicylic acid. PLoS Pathog. 2016;12(3):1–21.

Article  Google Scholar 

Ebeling W, Hennrich N, Klockow M, Metz H, Orth HD, Lang H. Proteinase K from Tritirachium album Limber. European J Biochem. 1974;47(1):91–7.

Article  CAS  Google Scholar 

Wertheim B, Kraaijeveld AR, Schuster E, Blanc E, Hopkins M, Pletcher SD, et al. Genome-wide gene expression in response to parasitoid attack in Drosophila. Genome Biol. 2005;6(11):R94.

Article  PubMed  PubMed Central  Google Scholar 

Clemmons AW, Lindsay SA, Wasserman SA. An effector peptide family required for Drosophila Toll-mediated immunity. PLoS Pathogens. 2015;11(4):e1004876.

Article  PubMed  PubMed Central  Google Scholar 

Clemmons AW, Lindsay SA, Wasserman SA. An effector peptide family required for Drosophila Toll-mediated immunity. Silverman N, editor. PLoS Pathog. 2015;11(4):e1004876.

Article  PubMed  PubMed Central  Google Scholar 

Lagueux M, Perrodou E, Levashina EA, Capovilla M, Hoffmann JA. Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants of Drosophila. Proc Natl Acad Sci. 2002;97(21):11427–32.

Article  Google Scholar 

Honti V, Csordás G, Kurucz É, Márkus R, Andó I. The cell-mediated immunity of Drosophila melanogaster: hemocyte lineages, immune compartments, microanatomy and regulation. Dev Comp Immunol. 2014;42(1):47–56.

Article  CAS  PubMed  Google Scholar 

Newman AM, Steen CB, Liu CL, Gentles AJ, Chaudhuri AA, Scherer F, et al. Determining cell type abundance and expression from bulk tissues with digital cytometry. Nat Biotechnol. 2019;37(7):773–82.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kumar S, Stecher G, Suleski M, Hedges SB. TimeTree: a resource for timelines, timetrees, and divergence times. Mol Biol Evol. 2017;34(7):1812–9.

Article  CAS  PubMed  Google Scholar 

Kenmoku H, Hori A, Kuraishi T, Kurata S. A novel mode of induction of the humoral innate immune response in Drosophila larvae. Dis Model Mech. 2017;10(3):271–81.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Madhwal S, Shin M, Kapoor A, Goyal M, Joshi MK, Rehman PMU, et al. Metabolic control of cellular immunecompetency by odors in drosophila. eLife. 2020;9:e60376.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rizki R, Rizki TM. Hemocyte responses to implanted tissues in Drosophila melanogaster larvae. Hereditas. 1980;250(2):602–220.

Google Scholar 

Matzinger P. The danger model: a renewed sense of self. Science. 2002;296(5566):301–5.

Article  CAS  PubMed  Google Scholar 

Sadd BM, Siva-Jothy MT. Self-harm caused by an insect’s innate immunity. Proceedings of the Royal Society B: Biological Sciences. 2006;273(1600):2571–4.

Article  PubMed Central  Google Scholar 

Bajgar A, Kucerova K, Jonatova L, Tomcala A, Schneedorferova I, Okrouhlik J, et al. Extracellular adenosine mediates a systemic metabolic switch during immune response. PLoS Biol. 2015;13(4):1–23.

Article  Google Scholar 

Atkinson BG, Dean RL, Tomlinson J, Blaker TW. Rapid purification of ferritin from lysates of red blood cells using proteinase-K. Biochem Cell Biol. 1989;67(1):52–7.

Article  CAS  PubMed  Google Scholar 

Butler GH, Kotani H, Kong L, Frick M, Evancho S, Stanbridge EJ, et al. Identification and characterization of proteinase K-resistant proteins in members of the class Mollicutes. Infect Immun. 1991;59(3):1037–42.

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