Krag DN, Anderson SJ, Julian TB, Brown AM, Harlow SP, Costantino JP, Ashikaga T, Weaver DL, Mamounas EP, Jalovec LM, Frazier TG, Noyes RD, Robidoux A, Scarth M, Wolmark H. Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial. Lancet Oncol. 2010;11:927–33. https://doi.org/10.1016/S1470-2045(10)70207-2

Article  PubMed  PubMed Central  Google Scholar 

Veronesi U, Paganelli G, Viale G, Luini A, Zurrida S, Galimberti V, Intra M, Veronesi P, Robertson C, Maisonneuve P, Renne G, De Cicco C, De Lucia F. Gennari, R. A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer. N Engl J Med. 2003;349:546–53. https://doi.org/10.1056/NEJMoa012782

Article  PubMed  Google Scholar 

Boler DE, Uras C, Ince U, Cabioglu N. Factors predicting the non-sentinel lymph node involvement in breast cancer patients with sentinel lymph node metastases. Breast. 2012;21:518–23. https://doi.org/10.1016/j.breast.2012.02.012

Article  CAS  PubMed  Google Scholar 

Giuliano AE, Ballman KV, McCall L, Beitsch PD, Brennan MB, Kelemen PR, Ollila DW, Hansen NM, Whitworth PW, Blumencranz PW, Leitch AM, Saha S, Hunt KK, Morrow M. Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis: the ACOSOG Z0011 (Alliance) randomized clinical trial. JAMA. 2017;318(10):918–26. https://doi.org/10.1001/jama.2017.11470

Article  PubMed  PubMed Central  Google Scholar 

Thomas M, Kelly ED, Abraham J, Kruse M. Invasive lobular breast cancer: a review of pathogenesis, diagnosis, management, and future directions of early-stage disease. Semin Oncol. 2019;46:121–32. https://doi.org/10.1053/j.seminoncol.2019.03.002

Article  PubMed  Google Scholar 

Hoda SA, Brogi E, Koerner FC, Rosen PP. Rosen’s breast pathology. 4th ed. Philadelphia: Lippincott Williams and Wilkins; 2014. pp. 855–92.

Google Scholar 

Cristofanilli M, Gonzalez-Angulo A, Sneige N, Kau SW, Broglio K, Theriault RL, Valero V, Buzdar AU, Kuerer H, Buchholz TA, Hortobagyi GN. Invasive lobular carcinoma classic type: response to primary chemotherapy and survival outcomes. J Clin Oncol. 2005;23:41–8. https://doi.org/10.1200/JCO.2005.03.111

Article  PubMed  Google Scholar 

Amadori D, Silvestrini R, De Lena M, Boccardo F, Rocca A, Scarpi E, Schittulli F, Brandi M, Maltoni R, Serra P, Ponzone R, Biglia N, Gianni L, Tienghi A, Valerio MR, Bonginelli P, Amaducci L, Faedi M, Baldini E, Paradiso A. Randomized phase III trial of adjuvant epirubicin followed by cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) versus CMF followed by epirubicin in patients with node-negative or 1–3 node-positive rapidly proliferating breast cancer. Breast Cancer Res Treat. 2011;125(3):775–84. https://doi.org/10.1007/s10549-010-1257-5

Article  CAS  PubMed  Google Scholar 

Roberts A, Nofech-Mozes S, Youngson B, McCready DR, Al-Assi M, Ramkumar S, Cil T. The importance of applying ACOSOG Z0011 criteria in the axillary management of invasive lobular carcinoma: a multi-institutional cohort study. Ann Surg Oncol. 2015;22(10):3397–401. https://doi.org/10.1245/s10434-015-4756-0

Article  PubMed  Google Scholar 

Adachi Y, Sawaki M, Hattori M, Yoshimura A, Gondo N, Kotani H, Iwase M, Kataoka A, Onishi S, Sugino K, Terada M, Horisawa N, Mori M, Oze I, Iwata H. Comparison of sentinel lymph node biopsy between invasive lobular carcinoma and invasive ductal carcinoma. Breast Cancer. 2018;25(5):560–5. https://doi.org/10.1007/s12282-018-0852-x

Article  PubMed  Google Scholar 

Gao W, Zeng Y, Fei X, Chen X, Shen K. Axillary lymph node and non-sentinel lymph node metastasis among the ACOSOG Z0011 eligible breast cancer patients with invasive ductal, invasive lobular, or other histological special types: a multi-institutional retrospective analysis. Breast Cancer Res Treat. 2020;184:193–202. https://doi.org/10.1007/s10549-020-05842-9

Article  CAS  PubMed  Google Scholar 

Corona SP, Bortul M, Scomersi S, Scomersi S, Bigal C, Bottin C, Zanconati F, Fox SB, Giudici F, Generali D. Management of the axilla in breast cancer: outcome analysis in a series of ductal versus lobular invasive cancers. Breast Cancer Res Treat. 2020;180:735–45. https://doi.org/10.1007/s10549-020-05565-x

Article  CAS  PubMed  Google Scholar 

Cipolla C, Fricano S, Vieni S, Amato C, Napoli L, Graceffa G, Latteri S, Latteri MA. Validity of needle core biopsy in the histological characterisation of mammary lesions. Breast. 2006;15(1):76–80. https://doi.org/10.1016/j.breast.2005.01.007

Article  PubMed  Google Scholar 

Caruso G, Cipolla C, Costa R, Morabito A, Latteri S, Fricano S, Salerno S, Latteri MA. Lymphoscintigraphy with peritumoral injection versus lymphoscintigraphy with subdermal periareolar injection of technetium-labeled human albumin to identify sentinel lymph nodes in breast cancer patients. Acta Radiol. 2014;55:39–44. https://doi.org/10.1177/0284185113493775

Article  PubMed  Google Scholar 

Cipolla C, Vieni S, Fricano S, Cabibi D, Graceffa G, Costa R, Latteri S, Latteri M. The accuracy of sentinel lymph node biopsy in the treatment of multicentric invasive breast cancer using a subareolar injection of tracer. World J Surg. 2008;32:2483–7. https://doi.org/10.1007/s00268-008-9719-1

Article  PubMed  Google Scholar 

Cipolla C, Graceffa G, Cabibi D, Gangi G, Latteri M, Valerio MR, Vieni S. Current role of intraoperative frozen section examination of sentinel lymph node in early breast cancer. Anticancer Res. 2020;40:1711–7. https://doi.org/10.21873/anticanres.14124

Article  PubMed  Google Scholar 

Pestalozzi BC, Zahrieh D, Mallon E, Gusterson BA, Price KN, Gelber RD, Holmberg SB, Lindtner J, Snyder R, Thürlimann B, Murray E, Viale G, Castiglione-Gertsch M, Coates AS, Goldhirsch A. International breast Cancer Study. Distinct clinical and prognostic features of infiltrating lobular carcinoma of the breast: combined results of 15 international breast Cancer Study Group clinical trials. J Clin Oncol. 2008;26:3006–14. https://doi.org/10.1200/JCO.2007.14.9336

Article  PubMed  Google Scholar 

Arpino G, Bardou VJ, Clark GM, Elledge RM. Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome. Breast Cance R Res. 2004;6:149–56. https://doi.org/10.1186/bcr767

Article  Google Scholar 

Cazzaniga ME, Airoldi M, Arcangeli V, Artale S, Atzori F, Ballerio A, et al. Efficacy and safety of everolimus and exemestane in hormone-receptor positive (HR+) human-epidermal-growth-factor negative (HER2–) advanced breast cancer patients: new insights beyond clinical trials. EVA Study Breast. 2017;35:115–21. https://doi.org/10.1016/j.breast.2017.06.043

Article  CAS  PubMed  Google Scholar 

Lambert LA, Ayers GD, Meric-Bernstam F. Validation of a breast cancer nomogram for predicting non-sentinel lymph node metastases after a positive sentinel node biopsy. Ann Surg Oncol. 2007;14:2422–3. https://doi.org/10.1245/s10434-007-9419-3

Article  CAS  PubMed  Google Scholar 

Krasniqi E, Pizzuti L, Barchiesi G, Sergi D, Carpano S, Botti C. Impact of BMI on HER2 + metastatic breast cancer patients treated with pertuzumab and/or trastuzumab emtansine. Real-world evidence. J Cell Physiol. 2020;235(11):7900–10. https://doi.org/10.1002/jcp.29445

Article  CAS  PubMed  Google Scholar 

Fernández B, Paish EC, Green AR, Lee AH, Macmillan RD, Ellis IO, Rakha EA. Lymph-node metastases in invasive lobular carcinoma are different from those in ductal carcinoma of the breast. J Clin Pathol. 2011;64:995–1000. https://doi.org/10.1136/jclinpath-2011-200151

Article  PubMed  Google Scholar 

Majid S, Rydén L, Manjer J. Determinants for non-sentinel node metastases in primary invasive breast cancer: a population-based cohort study of 602 consecutive patients with sentinel node metastases. BMC Cancer. 2019;19(1):626. https://doi.org/10.1186/s12885-019-5823-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Corona SP, Bortul M, Scomersi S, Bigal C, Bottin C, Zanconati F, Fox SB, Giudici F, Generali D. Management of the axilla in breast cancer: outcome analysis in a series of ductal versus lobular invasive cancers. Breast Cancer Res Treat. 2020;180:735–45. https://doi.org/10.1007/s10549-020-05565-x

Article  CAS  PubMed  Google Scholar 

Viale G, Maiorano E, Pruneri G, Mastropasqua MG, Valentini S, Galimberti V, Zurrida S, Maisonneuve P, Paganelli G, Mazzarol G. Predicting the risk for additional axillary metastases in patients with breast carcinoma and positive sentinel lymph node biopsy. Ann Surg. 2005;241:319–25. https://doi.org/10.1097/01.sla.0000150255.30665.52

Article  PubMed  PubMed Central  Google Scholar 

Christgen M, Derksen P. Lobular breast cancer: molecular basis, mouse and cellular models. Breast Cancer Res. 2015;17:16. https://doi.org/10.1186/s13058-015-0517-z

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kohrt HE, Olshen RA, Bermas HR, Goodson WH, Wood DJ, Henry S, Rouse RV, Bailey L, Philben VJ, Dirbas FM, Dunn JJ, Johnson DL, Wapnir IL, Carlson RW, Stockdale FE, Hansen NM, Jeffrey SS. & Bay Area SLN Study. New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients. BMC Cancer. 2008;8:66. https://doi.org/10.1186/1471-2407-8-66

Article  PubMed  PubMed Central  Google Scholar 

Abdessalam SF, Zervos EE, Prasad M, Farrar WB, Yee LD, Walker MJ, Carson WB, Burak WE. Jr. Predictors of positive axillary lymph nodes after sentinel lymph node biopsy in breast cancer. Am J Surg. 2001;182:316–20. https://doi.org/10.1016/s0002-9610(01)00719-x

Article  CAS  PubMed  Google Scholar 

Donker M, van Tienhoven G, Straver ME, Meijnen P, van de Velde CJ, Mansel RE, Cataliotti L, Westenberg AH, Klinkenbijl JH, Orzalesi L, Bouma WH, van der Mijle HC, Nieuwenhuijzen GA, Veltkamp SC, Slaets L, Duez NJ, de Graaf PW, van Dalen T, Marinelli A, Rijna H, Snoj M, Bundred NJ, Merkus JW, Belkacemi Y, Petignat P, Schinagl DA, Coens C, Messina CG, Bogaerts J, Rutgers EJ. Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981–22023 AMAROS): a randomised, multicentre, open-label, phase 3 noninferiority trial. Lancet Oncol. 2014;15:1303–10. https://doi.org/10.1016/S1470-2045(14)70460-7

Article  PubMed  PubMed Central  Google Scholar 

Zhang J, Ling Y, Wang T, Yan C, Huang M, Fan Z, Ling R. Chinese Society of Breast Cancer. Analysis of sentinel lymph node biopsy and non-sentinel lymph node metastasis in invasive ductal and invasive lobular breast cancer: a nationwide cross-sectional study (CSBrS-001). Ann Transl Med. 2021;9(20):1588. https://doi.org/10.21037/atm-21-5169

Article  CAS  PubMed  PubMed Central