Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M (2006) Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 160(1):1–40

Article  CAS  PubMed  Google Scholar 

Khanna KK, Jackson SP (2001) DNA double-strand breaks: signaling, repair and the cancer connection. Nat Genet 27(3):247–254

Article  CAS  PubMed  Google Scholar 

Lindahl T (1993) Instability and decay of the primary structure of DNA. Nature 362(6422):709–715

Article  CAS  PubMed  Google Scholar 

De Bont R, van Larebeke N (2004) Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis 19(3):169–185

Article  PubMed  Google Scholar 

Yousefzadeh M, Henpita C, Vyas R, Soto-Palma C, Robbins P, Niedernhofer L (2021) DNA damage—how and why we age? Elife 10:e62852

Article  CAS  PubMed  PubMed Central  Google Scholar 

Harper JW, Elledge SJ (2007) The DNA damage response: ten years after. Mol Cell 28(5):739–745

Article  CAS  PubMed  Google Scholar 

Rouse J, Jackson SP (2002) Interfaces between the detection, signaling, and repair of DNA damage. Science 297(5581):547–551

Article  CAS  PubMed  Google Scholar 

David SS, O’Shea VL, Kundu S (2007) Base-excision repair of oxidative DNA damage. Nature 447(7147):941–950

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hoeijmakers JH (2001) Genome maintenance mechanisms for preventing cancer. Nature 411(6835):366–374

Article  CAS  PubMed  Google Scholar 

Jiricny J (2006) The multifaceted mismatch-repair system. Nat Rev Mol Cell Biol 7(5):335–346

Article  CAS  PubMed  Google Scholar 

San Filippo J, Sung P, Klein H (2008) Mechanism of eukaryotic homologous recombination. Annu Rev Biochem 77:229–257

Article  CAS  PubMed  Google Scholar 

Lieber MR, Ma Y, Pannicke U, Schwarz K (2003) Mechanism and regulation of human non-homologous DNA end-joining. Nat Rev Mol Cell Biol 4(9):712–720

Article  CAS  PubMed  Google Scholar 

Deans AJ, West SC (2011) DNA interstrand crosslink repair and cancer. Nat Rev Cancer 11(7):467–480

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jackson SP, Bartek J (2009) The DNA-damage response in human biology and disease. Nature 461(7267):1071–1078

Article  CAS  PubMed  PubMed Central  Google Scholar 

Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124(4):783–801

Article  CAS  PubMed  Google Scholar 

Negishi H, Taniguchi T, Yanai H (2018) The interferon (IFN) class of cytokines and the IFN regulatory factor (IRF) transcription factor family. Cold Spring Harb Perspect Biol 10(11):a028423

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ivashkiv LB, Donlin LT (2014) Regulation of type I interferon responses. Nat Rev Immunol 14(1):36–49

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li W, Lu L, Lu J et al (2020) cGAS-STING-mediated DNA sensing maintains CD8(+) T cell stemness and promotes antitumor T cell therapy. Sci Transl Med 12(549):eaay9013

Article  CAS  PubMed  Google Scholar 

Wang X, Zhang H, Wang Y et al (2023) DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T-cell immunity. EMBO J 42(8):e110597

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kawanishi S, Hiraku Y, Pinlaor S, Ma N (2006) Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol Chem 387(4):365–372

Article  CAS  PubMed  Google Scholar 

Boeing S, Williamson L, Encheva V et al (2016) Multiomic analysis of the UV-induced DNA damage response. Cell Rep 15(7):1597–1610

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sutherland BM, Bennett PV, Sidorkina O, Laval J (2000) Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation. Proc Natl Acad Sci USA 97(1):103–108

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barnes DE, Lindahl T (2004) Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu Rev Genet 38:445–476

Article  CAS  PubMed  Google Scholar 

David SS, Williams SD (1998) Chemistry of glycosylases and endonucleases involved in base-excision repair. Chem Rev 98(3):1221–1262

Article  CAS  PubMed  Google Scholar 

Fromme JC, Verdine GL (2004) Base excision repair. Adv Protein Chem 69:1–41

Article  CAS  PubMed  Google Scholar 

Hegde ML, Hazra TK, Mitra S (2010) Functions of disordered regions in mammalian early base excision repair proteins. Cell Mol Life Sci 67(21):3573–3587

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lindahl T (2001) Keynote: past, present, and future aspects of base excision repair. Prog Nucleic Acid Res Mol Biol 68:xvii–xxx

Article  CAS  PubMed  Google Scholar 

Souliotis VL, Vlachogiannis NI, Pappa M, Argyriou A, Ntouros PA, Sfikakis pp (2019) DNA damage response and oxidative stress in systemic autoimmunity. Int J Mol Sci 21(1):55

Article  PubMed  PubMed Central  Google Scholar 

Dogliotti E, Fortini P, Pascucci B, Parlanti E (2001) The mechanism of switching among multiple BER pathways. Prog Nucleic Acid Res Mol Biol 68:3–27

Article  CAS  PubMed  Google Scholar 

Fortini P, Parlanti E, Sidorkina OM, Laval J, Dogliotti E (1999) The type of DNA glycosylase determines the base excision repair pathway in mammalian cells. J Biol Chem 274(21):15230–15236

Article  CAS  PubMed  Google Scholar 

Krokan HE, Bjoras M (2013) Base excision repair. Cold Spring Harb Perspect Biol 5(4):a012583

Article  PubMed  PubMed Central  Google Scholar 

Ding Y, Gui X, Chu X et al (2023) MTH1 protects platelet mitochondria from oxidative damage and regulates platelet function and thrombosis. Nat Commun 14(1):4829

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lindahl T, Barnes DE (2000) Repair of endogenous DNA damage. Cold Spring Harb Symp Quant Biol 65:127–133

Article  CAS  PubMed  Google Scholar 

Lindahl T, Wood RD (1999) Quality control by DNA repair. Science 286(5446):1897–1905

Article  CAS  PubMed  Google Scholar 

Cleaver JE, Lam ET, Revet I (2009) Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity. Nat Rev Genet 10(11):756–768

Article  CAS  PubMed  Google Scholar 

Groisman R, Polanowska J, Kuraoka I et al (2003) The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. Cell 113(3):357–367

Article  CAS  PubMed  Google Scholar 

Bregman DB, Halaban R, van Gool AJ, Henning KA, Friedberg EC, Warren SL (1996) UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in cockayne syndrome cells. Proc Natl Acad Sci USA 93(21):11586–11590

Article  CAS  PubMed  PubMed Central