Magliano, D., Boyko, E. J. & IDF Diabetes Atlas 10th Edition Scientific Committee. in IDF Diabetes Atlas (eds Boyko, E. J. et al.) Ch. 3, Global picture (International Diabetes Federation, 2021); https://diabetesatlas.org/atlas/tenth-edition/
ElSayed, N. A. et al. 15. Management of diabetes in pregnancy: standards of care in diabetes—2023. Diabetes Care 46, S254–S266 (2023).
Article CAS PubMed Google Scholar
Catalano, P. M., Kirwan, J. P., Haugel-de Mouzon, S. & King, J. Gestational diabetes and insulin resistance: role in short- and long-term implications for mother and fetus. J. Nutr. 133, 1674S–1683S (2003).
Article CAS PubMed Google Scholar
Barbour, L. A. et al. Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetes. Diabetes Care 30, S112–S119 (2007).
Article CAS PubMed Google Scholar
Sun, Y. et al. Increasing insulin resistance predicts adverse pregnancy outcomes in women with gestational diabetes mellitus. J. Diabetes 12, 438–446 (2020).
Article CAS PubMed Google Scholar
Li, J. et al. Roles of insulin resistance and beta cell dysfunction in macrosomia among Chinese women with gestational diabetes mellitus. Prim. Care Diabetes 12, 565–573 (2018).
Article PubMed PubMed Central Google Scholar
Wang, N. et al. Contribution of gestational diabetes mellitus heterogeneity and prepregnancy body mass index to large‐for‐gestational‐age infants—a retrospective case–control study. J. Diabetes 13, 307–317 (2021).
Article CAS PubMed Google Scholar
Madsen, L. R. et al. Do variations in insulin sensitivity and insulin secretion in pregnancy predict differences in obstetric and neonatal outcomes? Diabetologia 64, 304–312 (2021).
Article CAS PubMed Google Scholar
Immanuel, J. et al. Metabolic phenotypes of early gestational diabetes mellitus and their association with adverse pregnancy outcomes. Diabet. Med. 38, e14413 (2021).
Article CAS PubMed Google Scholar
Powe, C. E. et al. Heterogeneous contribution of insulin sensitivity and secretion defects to gestational diabetes mellitus. Diabetes Care 39, 1052–1055 (2016).
Article CAS PubMed PubMed Central Google Scholar
Beck, P. & Daughaday, W. H. Human placental lactogen: studies of its acute metabolic effects and disposition in normal man. J. Clin. Invest. 46, 103–110 (1967).
Article CAS PubMed PubMed Central Google Scholar
Kirwan, J. P. et al. TNF-alpha is a predictor of insulin resistance in human pregnancy. Diabetes 51, 2207–2213 (2002).
Article CAS PubMed Google Scholar
Powe, C. E., Huston Presley, L. P., Locascio, J. J. & Catalano, P. M. Augmented insulin secretory response in early pregnancy. Diabetologia 62, 1445–1452 (2019).
Article CAS PubMed PubMed Central Google Scholar
García-Patterson, A. et al. Insulin requirements throughout pregnancy in women with type 1 diabetes mellitus: three changes of direction. Diabetologia 53, 446–451 (2010).
Thaweethai, T., Soetan, Z., James, K., Florez, J. C. & Powe, C. E. Distinct insulin physiology trajectories in euglycemic pregnancy and gestational diabetes mellitus. Diabetes Care 46, 2137–2146 (2023).
Uhlén, M. et al. Proteomics. Tissue-based map of the human proteome. Science 347, 1260419 (2015).
Duan, C. & Xu, Q. Roles of insulin-like growth factor (IGF) binding proteins in regulating IGF actions. Gen. Comp. Endocrinol. 142, 44–52 (2005).
Article CAS PubMed Google Scholar
Petersson, U., Ostgren, C. J., Brudin, L., Brismar, K. & Nilsson, P. M. Low levels of insulin-like growth-factor-binding protein-1 (IGFBP-1) are prospectively associated with the incidence of type 2 diabetes and impaired glucose tolerance (IGT): the Söderåkra Cardiovascular Risk Factor Study. Diabetes Metab. 35, 198–205 (2009).
Article CAS PubMed Google Scholar
Hagström, H., Stål, P., Hultcrantz, R., Brismar, K. & Ansurudeen, I. IGFBP-1 and IGF-I as markers for advanced fibrosis in NAFLD—a pilot study. Scand. J. Gastroenterol. 52, 1427–1434 (2017).
Rajpathak, S. N. et al. Insulin-like growth factor axis and risk of type 2 diabetes in women. Diabetes 61, 2248–2254 (2012).
Article CAS PubMed PubMed Central Google Scholar
Guillemette, L. et al. Genetics of glucose regulation in gestation and growth (Gen3G): a prospective prebirth cohort of mother-child pairs in Sherbrooke, Canada. BMJ Open 6, e010031 (2016).
Article PubMed PubMed Central Google Scholar
Kirwan, J. P., Huston-Presley, L., Kalhan, S. C. & Catalano, P. M. Clinically useful estimates of insulin sensitivity during pregnancy: validation studies in women with normal glucose tolerance and gestational diabetes mellitus. Diabetes Care 24, 1602–1607 (2001).
Article CAS PubMed Google Scholar
Martín-Estal, I. & Castorena-Torres, F. Gestational diabetes mellitus and energy-dense diet: what is the role of the insulin/IGF axis? Front. Endocrinol. 13, 916042 (2022).
Suryawanshi, H. et al. A single-cell survey of the human first-trimester placenta and decidua. Sci. Adv. 4, eaau4788 (2018).
Article CAS PubMed PubMed Central Google Scholar
Bae, J.-H., Song, D.-K. & Im, S.-S. Regulation of IGFBP-1 in metabolic diseases. J. Lifestyle Med. 3, 73–79 (2013).
PubMed PubMed Central Google Scholar
Gao, J., Mazella, J., Suwanichkul, A., Powell, D. R. & Tseng, L. Activation of the insulin-like growth factor binding protein-1 promoter by progesterone receptor in decidualized human endometrial stromal cells. Mol. Cell. Endocrinol. 153, 11–17 (1999).
Article CAS PubMed Google Scholar
Goldsmith, L. T. & Weiss, G. Relaxin in human pregnancy. Ann. N. Y. Acad. Sci. 1160, 130–135 (2009).
Article CAS PubMed Google Scholar
Powell, D. R. et al. Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1. J. Biol. Chem. 266, 18868–18876 (1991).
Article CAS PubMed Google Scholar
Lewitt, M. S., Dent, M. S. & Hall, K. The insulin-like growth factor system in obesity, insulin resistance and type 2 diabetes mellitus. J. Clin. Med. 3, 1561–1574 (2014).
Article PubMed PubMed Central Google Scholar
Qiao, L. et al. Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1. Diabetologia 59, 2417–2425 (2016).
Article CAS PubMed PubMed Central Google Scholar
Kaur, H., Muhlhausler, B. S., Roberts, C. T. & Gatford, K. L. The growth hormone-insulin like growth factor axis in pregnancy. J. Endocrinol. 251, R23–R29 (2021).
Laager, R., Ninnis, R. & Keller, U. Comparison of the effects of recombinant human insulin-like growth factor-I and insulin on glucose and leucine kinetics in humans. J. Clin. Invest. 92, 1903–1909 (1993).
Article CAS PubMed PubMed Central Google Scholar
Jacob, R., Barrett, E., Plewe, G., Fagin, K. D. & Sherwin, R. S. Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat. Comparison with insulin. J. Clin. Invest. 83, 1717–1723 (1989).
Article CAS PubMed PubMed Central Google Scholar
Clemmons, D. R., Sleevi, M., Allan, G. & Sommer, A. Effects of combined recombinant insulin-like growth factor (IGF)-I and IGF binding protein-3 in type 2 diabetic patients on glycemic control and distribution of IGF-I and IGF-II among serum binding protein complexes. J. Clin. Endocrinol. Metab. 92, 2652–2658 (2007).
Article CAS PubMed Google Scholar
Scavo, L. M., Karas, M., Murray, M. & Leroith, D. Insulin-like growth factor-I stimulates both cell growth and lipogenesis during differentiation of human mesenchymal stem cells into adipocytes. J. Clin. Endocrinol. Metab. 89, 3543–3553 (2004).
Article CAS PubMed Google Scholar
Sferruzzi-Perri, A. N. Regulating needs: exploring the role of insulin-like growth factor-2 signalling in materno-fetal resource allocation. Placenta 64, S16–S22 (2018).
Article CAS PubMed Google Scholar
Lopez-Tello, J. et al. Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene. Cell Metab. 35, 1195–1208.e6 (2023).
Article CAS PubMed Google Scholar
Oxvig, C. & Conover, C. A. The stanniocalcin-PAPP-A-IGFBP-IGF axis. J. Clin. Endocrinol. Metab. 108, 1624–1633 (2023).
留言 (0)