Membrane specificity of the human cholesterol transfer protein STARD4

Keywords

STARD4

StART domain

cholesterol

molecular simulations

liposome microarray-based assay

AbbreviationsSTARD4

Steroidogenic Acute Regulatory Protein-related Lipid-Transfer Domain 4

PIP2

Phosphatidylinositol biphosphates

LTPs

Lipid transfer proteins

StART

Steroidogenic acute regulatory protein (StAR)-related lipid-transfer

PI(4,5)P2

Phosphatidylinositol 4,5-bisphosphate

HMMM

highly mobile membrane-mimetic

POPC

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine

POPE

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine

POPS

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine

PSM

N-Palmitoylsphingomyelin

POPI

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol

CER180

N-stearoyl-D-erythro-sphingosine

DOPC

1,2-dioleoyl-sn-glycero-3-phosphocholine

DOPE

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

DOPS

1,2-dioleoyl-sn-glycero-3-phospho-L-serine

PLPC

1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine

SAPC

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine

PSPE

1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine

SAPE

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine

SAPI

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol

SLPI

1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoinositol

POPA

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate

LiMA

Liposome micro-array based assay

NBI

Normalized binding intensity

Data availability

All the MD trajectories are uploaded to the Norwegian national infrastructure for research data (NIRD), have been issued a DOI (10.11582/2023.00138) and can be accessed using the following URL: https://doi.org/10.11582/2023.00138

© 2024 The Authors. Published by Elsevier Ltd.

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