Dysregulations of amino acid metabolism and lipid metabolism in urine of children and adolescents with major depressive disorder: a case-control study

Al Shweiki MR, Oeckl P, Steinacker P, Hengerer B, Schönfeldt-Lecuona C, Otto M (2017) Major depressive disorder: insight into candidate cerebrospinal fluid protein biomarkers from proteomics studies. Expert Rev Proteomics 14:499–514

Article  CAS  PubMed  Google Scholar 

Belenky P, Bogan KL, Brenner C (2007) NAD+ metabolism in health and disease. Trends Biochem Sci 32:12–19

Article  CAS  PubMed  Google Scholar 

Bouatra S, Aziat F, Mandal R, Guo AC, Wilson MR, Knox C, Bjorndahl TC, Krishnamurthy R, Saleem F, Liu P, Dame ZT, Poelzer J, Huynh J, Yallou FS, Psychogios N, Dong E, Bogumil R, Roehring C, Wishart DS (2013) The human urine metabolome. PLoS ONE 8:e73076

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bromet E, Andrade LH, Hwang I, Sampson NA, Alonso J, de Girolamo G, de Graaf R, Demyttenaere K, Hu C, Iwata N, Karam AN, Kaur J, Kostyuchenko S, Lépine JP, Levinson D, Matschinger H, Mora ME, Browne MO, Posada-Villa J, Viana MC, Williams DR, Kessler RC (2011) Cross-national epidemiology of DSM-IV major depressive episode. BMC Med 9:90

Article  PubMed  PubMed Central  Google Scholar 

Chambers MC, Maclean B, Burke R, Amodei D, Ruderman DL, Neumann S, Gatto L, Fischer B, Pratt B, Egertson J, Hoff K, Kessner D, Tasman N, Shulman N, Frewen B, Baker TA, Brusniak MY, Paulse C, Creasy D, Flashner L, Kani K, Moulding C, Seymour SL, Nuwaysir LM, Lefebvre B, Kuhlmann F, Roark J, Rainer P, Detlev S, Hemenway T, Huhmer A, Langridge J, Connolly B, Chadick T, Holly K, Eckels J, Deutsch EW, Moritz RL, Katz JE, Agus DB, MacCoss M, Tabb DL, Mallick P (2012) A cross-platform toolkit for mass spectrometry and proteomics. Nat Biotechnol 30:918–920

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen JJ, Liu Z, Fan SH, Yang DY, Zheng P, Shao WH, Qi ZG, Xu XJ, Li Q, Mu J, Yang YT, Xie P (2014) Combined application of NMR- and GC-MS-based metabonomics yields a superior urinary biomarker panel for bipolar disorder. Sci Rep 4:5855

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen JJ, Xie J, Li WW, Bai SJ, Wang W, Zheng P, Xie P (2019a) Age-specific urinary metabolite signatures and functions in patients with major depressive disorder. Aging (Albany N Y) 11:6626–6637

CAS  Google Scholar 

Chen JJ, Xie J, Zeng L, Zhou CJ, Zheng P, Xie P (2019b) Urinary metabolite signature in bipolar disorder patients during depressive episode. Aging (Albany N Y) 11:1008–1018

CAS  Google Scholar 

Chen DT, Cheng SW, Chen T, Chang JP, Hwang BF, Chang HH, Chuang EY, Chen CH, Su KP (2022) Identification of genetic variations in the NAD-related pathways for patients with major depressive disorder: a case-control study in Taiwan. J Clin Med 11(13):3622. https://doi.org/10.3390/jcm11133622

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cummings CM, Caporino NE, Kendall PC (2014) Comorbidity of anxiety and depression in children and adolescents: 20 years after. Psychol Bull 140:816–845

Article  PubMed  Google Scholar 

de Villiers M, Macuamule C, Spry C, Hyun YM, Strauss E, Saliba KJ (2013) Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity. ACS Med Chem Lett 4:784–789

Article  PubMed  PubMed Central  Google Scholar 

Dunn WB, Broadhurst D, Begley P, Zelena E, Francis-McIntyre S, Anderson N, Brown M, Knowles JD, Halsall A, Haselden JN, Nicholls AW, Wilson ID, Kell DB, Goodacre R (2011) Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat Protoc 6:1060–1083

Article  CAS  PubMed  Google Scholar 

Feng Y, Gao X, Meng M, Xue H, Qin X (2020) Multi-omics reveals the mechanisms of antidepressant-like effects of the low polarity fraction of Bupleuri Radix. J Ethnopharmacol 256:112806

Article  CAS  PubMed  Google Scholar 

Fiehn O, Robertson D, Griffin J, van der Werf M, Nikolau B, Morrison N, Sumner LW, Goodacre R, Hardy NW, Taylor C, Fostel J, Kristal B, Kaddurah-Daouk R, Mendes P, van Ommen B, Lindon JC, Sansone SA (2007) The metabolomics standards initiative (MSI). Metabolomics 3:175–178

Article  CAS  Google Scholar 

Francklyn CS, Mullen P (2019) Progress and challenges in aminoacyl-tRNA synthetase-based therapeutics. J Biol Chem 294:5365–5385

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gevi F, Zolla L, Gabriele S, Persico AM (2016) Urinary metabolomics of young Italian autistic children supports abnormal tryptophan and purine metabolism. Mol Autism 7:47

Article  PubMed  PubMed Central  Google Scholar 

Hankin BL, Young JF, Abela JR, Smolen A, Jenness JL, Gulley LD, Technow JR, Gottlieb AB, Cohen JR, Oppenheimer CW (2015) Depression from childhood into late adolescence: Influence of gender, development, genetic susceptibility, and peer stress. J Abnorm Psychol 124:803–816

Article  PubMed  PubMed Central  Google Scholar 

Hawton K, van Heeringen K (2009) Suicide. Lancet 373:1372–1381

Article  PubMed  Google Scholar 

Hazell P (2002) Depression in children. BMJ 325:229–230

Article  PubMed  PubMed Central  Google Scholar 

Kanehisa M, Goto S, Sato Y, Kawashima M, Furumichi M, Tanabe M (2014) Data, information, knowledge and principle: back to metabolism in KEGG. Nucleic Acids Res 42:D199-205

Article  CAS  PubMed  Google Scholar 

Kell DB (2004) Metabolomics and systems biology: making sense of the soup. Curr Opin Microbiol 7:296–307

Article  CAS  PubMed  Google Scholar 

Kessler RC, Bromet EJ (2013) The epidemiology of depression across cultures. Annu Rev Public Health 34:119–138

Article  PubMed  PubMed Central  Google Scholar 

Khamis MM, Adamko DJ, El-Aneed A (2017) Mass spectrometric based approaches in urine metabolomics and biomarker discovery. Mass Spectrom Rev 36:115–134

Article  CAS  PubMed  Google Scholar 

Krämer A, Green J, Pollard J Jr, Tugendreich S (2014) Causal analysis approaches in ingenuity pathway analysis. Bioinformatics 30:523–530

Article  PubMed  Google Scholar 

Liu X, Zheng P, Zhao X, Zhang Y, Hu C, Li J, Zhao J, Zhou J, Xie P, Xu G (2015) Discovery and validation of plasma biomarkers for major depressive disorder classification based on liquid chromatography-mass spectrometry. J Proteome Res 14:2322–2330

Article  CAS  PubMed  Google Scholar 

Liu X, Liu C, Tian J, Gao X, Li K, Du G, Qin X (2020) Plasma metabolomics of depressed patients and treatment with Xiaoyaosan based on mass spectrometry technique. J Ethnopharmacol 246:112219

Article  CAS  PubMed  Google Scholar 

Liu X, Wu X, Wang S, Zhao Z, Jian C, Li M, Qin X (2023) Microbiome and metabolome integrally reveal the anti-depression effects of Cistanche deserticola polysaccharides from the perspective of gut homeostasis. Int J Biol Macromol 245:125542

Article  CAS  PubMed  Google Scholar 

Lundervold AJ, Hinshaw SP, Sørensen L, Posserud MB (2016) Co-occurring symptoms of attention deficit hyperactivity disorder (ADHD) in a population-based sample of adolescents screened for depression. BMC Psychiatry 16:46

Article  PubMed  PubMed Central  Google Scholar 

Ma WN, Zhou MM, Gou XJ, Zhao L, Cen F, Xu Y, Shen HY (2018) Urinary metabolomic study of chlorogenic acid in a rat model of chronic sleep deprivation using gas chromatography-mass spectrometry. Int J Genomics 2018:1361402

Article  PubMed  PubMed Central  Google Scholar 

Manning BD, Toker A (2017) AKT/PKB signaling: navigating the network. Cell 169:381–405

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miller L, Campo JV (2021) Depression in adolescents. N Engl J Med 385:445–449

Article  CAS  PubMed  Google Scholar 

Mullen S (2018) Major depressive disorder in children and adolescents. Ment Health Clin 8:275–283

Article  PubMed  PubMed Central  Google Scholar 

Oliveira S, Ardais AP, Bastos CR, Gazal M, Jansen K, de Mattos SL, da Silva RA, Kaster MP, Lara DR, Ghisleni G (2019) Impact of genetic variations in ADORA2A gene on depression and symptoms: a cross-sectional population-based study. Purinergic Signal 15:37–44

Article  CAS  PubMed  Google Scholar 

O’Sullivan A, Gibney MJ, Brennan L (2011) Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies. Am J Clin Nutr 93:314–321

Article  CAS  PubMed  Google Scholar 

Pang Z, Chong J, Zhou G, de Lima Morais DA, Chang L, Barrette M, Gauthier C, Jacques P, Li S, Xia J (2021) MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights. Nucleic Acids Res 49:W388-w396

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pu J, Liu Y, Gui S, Tian L, Yu Y, Wang D, Zhong X, Chen W, Chen X, Chen Y, Chen X, Gong X, Liu L, Li W, Wang H, Xie P (2022) Effects of pharmacological treatment on metabolomic alt

留言 (0)

沒有登入
gif