Peng F, et al. Regulated cell death (RCD) in cancer: key pathways and targeted therapies. Signal Transduct Target Ther. 2022;7(1):286.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Koren E, Fuchs Y. Modes of regulated cell death in cancer. Cancer Discov. 2021;11(2):245–65.

Article  CAS  PubMed  Google Scholar 

Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wideranging implications in tissue kinetics. Br J Cancer. 1972;26(4):239–57.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carneiro BA, El-Deiry WS. Targeting apoptosis in cancer therapy. Nat Rev Clin Oncol. 2020;17(7):395–417.

Article  PubMed  PubMed Central  Google Scholar 

Morana O, Wood W, Gregory CD. The apoptosis paradox in cancer. Int J Mol Sci. 2022;23(3):1328.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Leak L, Dixon SJ. Surveying the landscape of emerging and understudied cell death mechanisms. Biochim BiophysActa (BBA) Mol Cell Res. 2023;1870(3):119432. https://doi.org/10.1016/j.bbamcr.2023.119432.

Article  CAS  Google Scholar 

Tang D, et al. The molecular machinery of regulated cell death. Cell Res. 2019;29(5):347–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang X, Stockwell BR, Conrad M. Ferroptosis: mechanisms, biology and role in disease. Nat Rev Mol Cell Biol. 2021;22(4):266–82.

Article  PubMed  PubMed Central  Google Scholar 

Obeng E. Apoptosis (programmed cell death) and its signals—a review. Braz J Biol. 2020;81:1133–43.

Article  Google Scholar 

D’arcy MS. Cell death: a review of the major forms of apoptosis, necrosis and autophagy. Cell Biol Int. 2019;43(6):582–92.

Article  PubMed  Google Scholar 

Tonnus W, et al. The pathological features of regulated necrosis. J Pathol. 2019;247(5):697–707.

Article  CAS  PubMed  Google Scholar 

Ichimiya T, et al. Autophagy and autophagy-related diseases: a review. Int J Mol Sci. 2020;21(23):8974.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cao W, et al. An overview of autophagy: mechanism, regulation and research progress. Bull Cancer. 2021;108(3):304–22.

Article  PubMed  Google Scholar 

Li J, et al. Ferroptosis: past, present and future. Cell Death Dis. 2020;11(2):88.

Article  PubMed  PubMed Central  Google Scholar 

Yan H-F, et al. Ferroptosis: mechanisms and links with diseases. Signal Transduct Target Ther. 2021;6(1):49.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang D, et al. Ferroptosis: molecular mechanisms and health implications. Cell Res. 2021;31(2):107–25.

Article  CAS  PubMed  Google Scholar 

Chen Z, et al. Ferroptosis as a potential target for cancer therapy. Cell Death Dis. 2023;14(7):460.

Article  PubMed  PubMed Central  Google Scholar 

Hangauer MJ, et al. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition. Nature. 2017;551(7679):247–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Viswanathan VS, et al. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Nature. 2017;547(7664):453–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu X, et al. Targeting ferroptosis pathway to combat therapy resistance and metastasis of cancer. Front Pharmacol. 2022;13: 909821.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lei G, Zhuang L, Gan B. Targeting ferroptosis as a vulnerability in cancer. Nat Rev Cancer. 2022;22(7):381–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bebber CM, et al. Ferroptosis in cancer cell biology. Cancers. 2020;12(1):164.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen EC, Garcia JS. Immunotherapy for acute myeloid leukemia: current trends, challenges, and strategies. Acta Haematol. 2023; 1–21.

Bayón-Calderón F, Toribio ML, González-García S. Facts and challenges in immunotherapy for T-cell acute lymphoblastic leukemia. Int J Mol Sci. 2020;21(20):7685.

Article  PubMed  PubMed Central  Google Scholar 

Tang L, et al. Immunotherapy in hematologic malignancies: achievements, challenges and future prospects. Signal Transduct Target Ther. 2023;8(1):306.

Article  PubMed  PubMed Central  Google Scholar 

Zheng X, et al. Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy. Exp Hematol Oncol. 2023;12(1):65.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang B, et al. Integrative analysis of the molecular mechanisms, immunological features and immunotherapy response of ferroptosis regulators across 33 cancer types. Int J Biol Sci. 2022;18(1):180.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Grignano E, et al. From iron chelation to overload as a therapeutic strategy to induce ferroptosis in leukemic cells. Front Oncol. 2020;10: 586530.

Article  PubMed  PubMed Central  Google Scholar 

Wang F, et al. Iron and leukemia: new insights for future treatments. J Exp Clin Cancer Res. 2019;38(1):1–17.

Article  Google Scholar 

Hunter RL, et al. Transferrin in disease II: defects in the regulation of transferrin saturation with iron contribute to susceptibility to infection. Am J Clin Pathol. 1984;81(6):748–53.

Article  CAS  PubMed  Google Scholar 

Kohnken R, Porcu P, Mishra A. Overview of the use of murine models in leukemia and lymphoma research. Front Oncol. 2017. https://doi.org/10.3389/fonc.2017.00022.

Article  PubMed  PubMed Central  Google Scholar 

Liu Q, et al. Ferroptosis: challenges and opportunities for nanomaterials in cancer therapy. Regen Biomater. 2023;10:rbad004.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yan D, Wu Z, Qi X. Ferroptosis-related metabolic mechanism and nanoparticulate anticancer drug delivery systems based on ferroptosis. Saudi Pharm J. 2023;31(4):554–68.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu M, et al. Nanomaterial-induced ferroptosis for cancer specific therapy. Coord Chem Rev. 2019;382:160–80.

Article  CAS  Google Scholar 

Cao JY, Dixon SJ. Mechanisms of ferroptosis. Cell Mol Life Sci. 2016;73(11–12):2195–209.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abaszadeh F, Ashoub MH, Amiri M. Nanoemulsions challenges and future prospects as a drug delivery system. In: Husen A, Bachheti RK, Bachheti A, editors. Current trends in green nano-emulsions: food, agriculture and biomedical sectors. Singapore: Springer Nature Singapore; 2023. p. 217–43.

Chapter  Google Scholar 

Zhang P, et al. Cancer nanomedicine toward clinical translation: obstacles, opportunities, and future prospects. Med. 2023;4(3):147–67.

Article  CAS  PubMed  Google Scholar 

Gkouvatsos K, Papanikolaou G, Pantopoulos K. Regulation of iron transport and the role of transferrin. Biochim Biophys Acta BBA 2012; 1820(3): 188–202.

Bogdan AR, et al. Regulators of iron homeostasis: new players in metabolism, cell death, and disease. Trends Biochem Sci. 2016;41(3):274–86.

Article  CAS  PubMed  Google Scholar 

Gao M, et al. Glutaminolysis and transferrin regulate ferroptosis. Mol Cell. 2015;59(2):298–308.

Article  CAS