Mitigation of letrozole induced polycystic ovarian syndrome associated inflammatory response and endocrinal dysfunction by Vitex negundo seeds

Health-Europe TL. Polycystic ovary syndrome: what more can be done for patients? Lancet Reg Health Eur. 2022;21:100524. https://doi.org/10.1016/j.lanepe.2022.100524.

Article  Google Scholar 

Kshetrimayum C, Sharma A, Mishra VV, Kumar S. Polycystic ovarian syndrome: Environmental/occupational, lifestyle factors; an overview. J Turk Ger Gynecol Assoc. 2019;20(4):255. https://doi.org/10.4274/jtgga.galenos.2019.2018.0142.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhai Y, Pang Y. Systemic and ovarian inflammation in women with polycystic ovary syndrome. J Reprod Immunol. 2022;151: 103628. https://doi.org/10.1016/j.jri.2022.103628.

Article  CAS  PubMed  Google Scholar 

Witchel SF, Oberfield SE, Peña AS. Polycystic ovary syndrome: pathophysiology, presentation, and treatment with emphasis on adolescent girls. J Endocr Soc. 2019;3(8):1545–73. https://doi.org/10.1210/js.2019-00078.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rocha AL, Oliveira FR, Azevedo RC, Silva VA, Peres TM, Candido AL, Gomes KB, Reis FM. Recent advances in the understanding and management of polycystic ovary syndrome. F1000Res. 2019;8. https://doi.org/10.12688/f1000research.15318.1.

Domecq JP, Prutsky G, Mullan RJ, Sundaresh V, Wang AT, Erwin PJ, Welt C, Ehrmann D, Montori VM, Murad MH. Adverse effects of the common treatments for polycystic ovary syndrome: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2013;98(12):4646–54. https://doi.org/10.1210/jc.2013-2374.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rashid R, Mir SA, Kareem O, Ali T, Ara R, Malik A, Amin F, Bader GN. Polycystic ovarian syndrome-current pharmacotherapy and clinical implications. Taiwan J Obstet Gynecol. 2022;61(1):40–50. https://doi.org/10.1016/j.tjog.2021.11.009.

Article  PubMed  Google Scholar 

Manouchehri A, Abbaszadeh S, Ahmadi M, Nejad FK, Bahmani M, Dastyar N. Polycystic ovaries and herbal remedies: a systematic review. JBRA Assist Reprod. 2023;27(1):85. https://doi.org/10.5935/1518-0557.20220024.

Article  PubMed  PubMed Central  Google Scholar 

Ganapaty S, Vidyadhar KN. Phytoconstituents and biological activities of Vitex-a review. J Nat Rremedies. 2005;75–95. https://doi.org/10.18311/jnr/2005/391.

Vishwanathan AS, Basavaraju R. A review on Vitex negundo L.: a medicinally important plant. Eur J Biol Sci. 2010;3(1):30–42.

Google Scholar 

Zheng CJ, Qin LP. Negundo Chastetree (Vitex negundo) oils. In: Essential oils in Food Preservation, Flavor and Safety. Academic; 2016. p. 601-6.

Kamal N, Mio Asni NS, Rozlan IN, Mohd Azmi MA, Mazlan NW, Mediani A, Baharum SN, Latip J, Assaw S, Edrada-Ebel RA. Traditional Medicinal uses, Phytochemistry, Biological Properties, and Health applications of Vitex Sp. Plants (Basel). 2022;11(15):1944. https://doi.org/10.3390/plants11151944.

Article  CAS  PubMed  Google Scholar 

Zheng CJ, Li HQ, Ren SC, Xu CL, Rahman K, Qin LP, Sun YH. Phytochemical and pharmacological profile of Vitex negundo. Phytother Res. 2015;29(5):633–47. https://doi.org/10.1002/ptr.5303.

Article  PubMed  Google Scholar 

Kakadia N, Patel P, Deshpande S, Shah G. Effect of Vitex negundo L. seeds in letrozole induced polycystic ovarian syndrome. J Tradit Complement Med. 2019;9(4):336–45. https://doi.org/10.1016/j.jtcme.2018.03.001.

Article  PubMed  Google Scholar 

Shetty DK, Patil S. Studying the Testosterone lowering potential of Vitex negundo (Nirgundi) seed extract in hyperandrogenic female rats Induced with Polycystic ovaries. Int J Pharm Sci Rev Res. 2015;33(1):211–6.

Google Scholar 

Saiyed A, Jahan N, Makbul SA, Ansari M, Bano H, Habib SH. Effect of combination of Withania somnifera Dunal and Tribulus terrestris Linn on letrozole induced polycystic ovarian syndrome in rats. Integr Med Res. 2016;5(4):293–300. https://doi.org/10.1016/j.imr.2016.10.002.

Article  PubMed  PubMed Central  Google Scholar 

Glueck CJ, Goldenberg N. Characteristics of obesity in polycystic ovary syndrome: etiology, treatment, and genetics. Metabolism. 2019;92:108–20. https://doi.org/10.1016/j.metabol.2018.11.002.

Article  CAS  PubMed  Google Scholar 

Kiddy DS, Sharp PS, White DM, Scanlon MF, Mason HD, Bray CS, Polson DW, Reed MJ, Franks S. Differences in clinical and endocrine features between obese and non-obese subjects with polycystic ovary syndrome: an analysis of 263 consecutive cases. Clin Endocrinol. 1990;32(2):213–20. https://doi.org/10.1111/j.1365-2265.1990.tb00857.x.

Article  CAS  Google Scholar 

Nath CK, Barman B, Das A, Rajkhowa P, Baruah P, Baruah M, Baruah A. Prolactin and thyroid stimulating hormone affecting the pattern of LH/FSH secretion in patients with polycystic ovary syndrome: a hospital-based study from North East India. J Family Med Prim Care. 2019;8(1):256. https://doi.org/10.4103/jfmpc.jfmpc_281_18.

Article  PubMed  PubMed Central  Google Scholar 

Lakshmi JN, Babu AN, Kiran SM, Nori LP, Hassan N, Ashames A, Bhandare RR, Shaik AB. Herbs as a source for the treatment of polycystic ovarian syndrome: a systematic review. Biotech. 2023;12(1):4. https://doi.org/10.3390/biotech12010004.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brožič P, Kocbek P, Sova M, Kristl J, Martens S, Adamski J, Gobec S, Rižner TL. Flavonoids and cinnamic acid derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 1. Mol Cell Endocrinol. 2009;301(1–2):229–34. https://doi.org/10.1016/j.mce.2008.09.004.

Article  CAS  PubMed  Google Scholar 

Arlt W, Neogi P, Gross C, Miller WL. Cinnamic acid based thiazolidinediones inhibit human P450c17 and 3beta-hydroxysteroid dehydrogenase and improve insulin sensitivity independent of PPARgamma agonist activity. J Mol Endocrinol. 2004;32(2):425–36. https://doi.org/10.1677/jme.0.0320425.

Article  CAS  PubMed  Google Scholar 

Ashraf S, Nabi M, Rashid F, Amin S. Hyperandrogenism in polycystic ovarian syndrome and role of CYP gene variants: a review. Egypt J Med Hum Genet. 2019;20(1):1–0. https://doi.org/10.1186/s43042-019-0031-4.

Article  Google Scholar 

Jakimiuk AJ, Weitsman SR, Yen HW, Bogusiewicz M, Magoffin DA. Estrogen receptor α and β expression in theca and granulosa cells from women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2002;87(12):5532–8. https://doi.org/10.1210/jc.2002-020323.

Article  CAS  PubMed  Google Scholar 

Roberts AJ, skinner MK. Estrogen regulation of thecal cell steroidogenesis and differentiation: thecal cell-granulosa cell interactions. Endocrinology. 1990;127(6):2918–29. https://doi.org/10.1210/endo-127-6-2918.

Article  CAS  PubMed  Google Scholar 

Dey A, Dhadhal S, Maharjan R, Nagar PS, Nampoothiri L. Partially purified non-polar phytocomponents from Aloe barbadensis Mill. Gel restores metabolic and reproductive comorbidities in letrozole-induced polycystic ovary syndrome rodent model-an in-vivo study. J Ethnopharmacol. 2022;291:115161. https://doi.org/10.1016/j.jep.2022.115161.

Article  CAS  PubMed  Google Scholar 

Manneras L, Cajander S, Holmäng A, Seleskovic Z, Lystig T, Lönn M, Stener-Victorin E. A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome. Endocrinology. 2007;148(8):3781–91. https://doi.org/10.1210/en.2007-0168.

Article  CAS  PubMed  Google Scholar 

Davey RA, Grossmann M. Androgen receptor structure, function and biology: from bench to bedside. Clin Biochem Rev. 2016;37(1):3.

PubMed  PubMed Central  Google Scholar 

Pereira de Jésus-Tran K, Côté PL, Cantin L, Blanchet J, Labrie F, Breton R. Comparison of crystal structures of human androgen receptor ligand‐binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity. Protein Sci. 2006;15(5):987–99. https://doi.org/10.1110/ps.051905906.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Unluhizarci K, Karaca Z, Kelestimur F. Role of insulin and insulin resistance in androgen excess disorders. World J Diabetes. 2021;12(5): 616.

Article  PubMed  PubMed Central  Google Scholar 

Adisakwattana S. Cinnamic acid and its derivatives: mechanisms for prevention and management of diabetes and its complications. Nutrients. 2017;9(2): 163. https://doi.org/10.3390/nu9020163.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sunil C, Duraipandiyan V, Agastian P, Ignacimuthu S. Antidiabetic effect of plumbagin isolated from Plumbago zeylanica L. root and its effect on GLUT4 translocation in streptozotocin-induced diabetic rats. Food Chem Toxicol. 2012;50(12):4356–63. https://doi.org/10.1016/j.fct.2012.08.046.

Article  CAS  PubMed  Google Scholar 

Zuo T, Zhu M, Xu W. Roles of oxidative stress in polycystic ovary syndrome and cancers. Oxid Med Cell Longev. 2016;2016:8589318. https://doi.org/10.1155/2016/8589318.

Article  CAS  PubMed  Google Scholar 

Sun Y, Li S, Liu H, Bai H, Hu K, Zhang R, Liu Q, Fan P. Oxidative stress promotes hyperandrogenism by reducing sex hormone-binding globulin in polycystic ovary syndrome. Fertil Steril. 2021;116(6):1641–50.

Article  CAS  PubMed  Google Scholar 

Siemers KM, Klein AK, Baack ML. Mitochondrial dysfunction in PCOS: insights into Reproductive Organ Pathophysiology. Int J Mol Sci. 2023;24(17): 13123. https://doi.org/10.3390/ijms241713123.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jahan S, Munir F, Razak S, Mehboob A, Ain QU, Ullah H, Afsar T, Shaheen G, Almajwal A. Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats. J Ovarian Res. 2016;9:1–9. https://doi.org/10.1186/s13048-016-0295-y.

留言 (0)

沒有登入
gif