Global post-mortem tissue donation programmes to accelerate cancer research

Coates, J. T. et al. Parallel genomic alterations of antigen and payload targets mediate polyclonal acquired clinical resistance to sacituzumab govitecan in triple-negative breast cancer. Cancer Discov. 11, 2436–2445 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Garcia-Recio, S. et al. Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis. Nat. Cancer 4, 128–147 (2023).

CAS  PubMed  Google Scholar 

Geukens, T. et al. Intra-patient and inter-metastasis heterogeneity of HER2-low status in metastatic breast cancer. Eur. J. Cancer 188, 152–160 (2023).

Article  CAS  PubMed  Google Scholar 

Hessey, S., Fessas, P., Zaccaria, S., Jamal-Hanjani, M. & Swanton, C. Insights into the metastatic cascade through research autopsies. Trends Cancer 9, 490–502 (2023).

Article  PubMed  Google Scholar 

Cresswell, G. D. et al. Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking. Nat. Commun. 11, 1446 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

De Mattos-Arruda, L. et al. The genomic and immune landscapes of lethal metastatic breast cancer. Cell Rep. 27, 2690–2708 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Al Bakir, M. et al. The evolution of non-small cell lung cancer metastases in TRACERx. Nature 616, 534–542 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Geukens, T. et al. Research autopsy programmes in oncology: shared experience from 14 centres across the world. J. Pathol. https://doi.org/10.1002/path.6271 (2024).

Quinn, G. P. et al. Altruism in terminal cancer patients and rapid tissue donation program: does the theory apply? Med. Health Care Philos. 16, 857–64 (2013).

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif