Genetic influences and causal pathways shared between cannabis use disorder and other substance use traits

Hasin DS, Kerridge BT, Saha TD, Huang B, Pickering R, Smith SM, et al. Prevalence and correlates of DSM-5 Cannabis Use Disorder, 2012-2013: findings from the national epidemiologic survey on alcohol and related conditions-III. Am J Psychiatry. 2016;173:588–99.

Article  PubMed  PubMed Central  Google Scholar 

McLellan AT. Substance misuse and substance use disorders: why do they matter in healthcare? Trans Am Clin Climatol Assoc. 2017;128:112–30.

PubMed  PubMed Central  Google Scholar 

Gan WQ, Buxton JA, Scheuermeyer FX, Palis H, Zhao B, Desai R, et al. Risk of cardiovascular diseases in relation to substance use disorders. Drug Alcohol Depend. 2021;229:109132.

Article  PubMed  Google Scholar 

Chen M, Lu Y-l, Chen X-f, Wang Z, Ma L. Association of cannabis use disorder with cardiovascular diseases: a two-sample Mendelian randomization study. Front Cardiovasc Med. 2022;9:966707.

Article  PubMed  PubMed Central  Google Scholar 

Yusufov M, Braun IM, Pirl WF. A systematic review of substance use and substance use disorders in patients with cancer. Gen Hospital Psychiatry. 2019;60:128–36.

Article  Google Scholar 

Sheikh Andalibi MS, Rezaei Ardani A, Amiri A, Morovatdar N, Talebi A, Azarpazhooh MR, et al. The association between substance use disorders and long-term outcome of stroke: results from a population-based study of stroke among 450,229 urban citizens. Neuroepidemiology. 2021;55:171–9.

Article  PubMed  Google Scholar 

Thylstrup B, Seid AK, Tjagvad C, Hesse M. Incidence and predictors of drug overdoses among a cohort of >10,000 patients treated for substance use disorder. Drug Alcohol Depend. 2020;206:107714.

Article  CAS  PubMed  Google Scholar 

Jones CM, McCance-Katz EF. Co-occurring substance use and mental disorders among adults with opioid use disorder. Drug Alcohol Depend. 2019;197:78–82.

Article  PubMed  Google Scholar 

Levey DF, Galimberti M, Deak JD, Wendt FR, Bhattacharya A, Koller D, et al. Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications. Nat Genet. 2023;55:2094–103.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Selamoglu A, Langley C, Crean R, Savulich G, Cormack F, Sahakian BJ, et al. Neuropsychological performance in young adults with cannabis use disorder. J Psychopharmacol. 2021;35:1349–55.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Compton WM, Saha TD, Conway KP, Grant BF. The role of cannabis use within a dimensional approach to cannabis use disorders. Drug Alcohol Depend. 2009;100:221–7.

Article  PubMed  Google Scholar 

Connor JP, Stjepanović D, Le Foll B, Hoch E, Budney AJ, Hall WD. Cannabis use and cannabis use disorder. Nat Rev Dis Prim. 2021;7:16.

Article  PubMed  Google Scholar 

Leung J, Chan GCK, Hides L, Hall WD. What is the prevalence and risk of cannabis use disorders among people who use cannabis? a systematic review and meta-analysis. Addic Behav. 2020;109:106479.

Article  Google Scholar 

Roberts E. What impact could the legalisation of recreational cannabis have on the health of the UK? Lessons from the rest of the world. Br J Psychiatry. 2024;224:117–8.

Zellers SM, Ross JM, Saunders GRB, Ellingson JM, Anderson JE, Corley RP, et al. Impacts of recreational cannabis legalization on cannabis use: a longitudinal discordant twin study. Addiction. 2023;118:110–8.

Article  PubMed  Google Scholar 

Zellers S, Alexander J, Ellingson JM, Schaefer JD, Corley RP, Iacono W, et al. Limited psychological and social effects of lifetime cannabis use frequency: Evidence from a 30-year community study of 4,078 twins. J Psychopathol Clin Sci. 2024;133:115–28.

Article  PubMed  Google Scholar 

Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, et al. A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry. 2020;7:1032–45.

Article  PubMed  PubMed Central  Google Scholar 

Zhou H, Kember RL, Deak JD, Xu H, Toikumo S, Yuan K, et al. Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. Nat Med. 2023;29:3184–92.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bulik-Sullivan B, Finucane HK, Anttila V, Gusev A, Day FR, Loh P-R, et al. An atlas of genetic correlations across human diseases and traits. Nat Genet. 2015;47:1236–41.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pasman JA, Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, et al. GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability. Nat Neurosci. 2018;21:1161–70.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deak JD, Zhou H, Galimberti M, Levey DF, Wendt FR, Sanchez-Roige S, et al. Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci. Mol Psychiatry. 2022;27:3970–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Saunders GRB, Wang X, Chen F, Jang S-K, Liu M, Wang C, et al. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature. 2022;612:720–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, et al. Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. Nat Commun. 2020;11:5562.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Werme J, van der Sluis S, Posthuma D, de Leeuw CA. An integrated framework for local genetic correlation analysis. Nat Genet. 2022;54:274–82.

Article  CAS  PubMed  Google Scholar 

Grotzinger AD, Rhemtulla M, de Vlaming R, Ritchie SJ, Mallard TT, Hill WD, et al. Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits. Nat Hum Behav. 2019;3:513–25.

Article  PubMed  PubMed Central  Google Scholar 

Auton A, Abecasis GR, Altshuler DM, Durbin RM, Abecasis GR, Bentley DR, et al. A global reference for human genetic variation. Nature. 2015;526:68–74.

Article  PubMed  Google Scholar 

Mounier N, Kutalik Z. Bias correction for inverse variance weighting Mendelian randomization. Genet Epidemiol. 2023;47:314–31.

Article  CAS  PubMed  Google Scholar 

Gelernter J, Polimanti R. Genetics of substance use disorders in the era of big data. Nat Rev Genet. 2021;22:712–29.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jang S-K, Jiang Y, Liu M, Liu DJ, Saunders G, Vrieze S. Genetic correlation, pleiotropy, and causal associations between substance use and psychiatric disorder. Psychol Med. 2020;52:968–78.

Article  PubMed  PubMed Central  Google Scholar 

Abdellaoui A, Verweij KJH. Dissecting polygenic signals from genome-wide association studies on human behaviour. Nat Hum Behav. 2021;5:686–94.

Article  PubMed  Google Scholar 

Wilson J, Mills K, Freeman TP, Sunderland M, Visontay R, Marel C. Weeding out the truth: a systematic review and meta-analysis on the transition from cannabis use to opioid use and opioid use disorders, abuse or dependence. Addiction. 2022;117:284–98.

Article  PubMed  Google Scholar 

Olfson M, Wall MM, Liu SM, Blanco C. Cannabis use and risk of prescription opioid use disorder in the United States. Am J Psychiatry. 2018;175:47–53.

Article  PubMed  Google Scholar 

Sanchez-Roige S, Palmer AA, Fontanillas P, Elson SL, Adams MJ, Howard DM, et al. Genome-wide association study meta-analysis of the Alcohol Use Disorders Identification Test (AUDIT) in two population-based cohorts. Am J Psychiatry. 2019;176:107–18.

Article  PubMed  Google Scholar 

Metrik J, Gunn RL, Jackson KM, Sokolovsky AW, Borsari B. Daily patterns of marijuana and alcohol co-use among individuals with alcohol and cannabis use disorders. Alcohol: Clin Exp Res. 2018;42:1096–104.

Article  PubMed  Google Scholar 

Weinberger AH, Platt J, Goodwin RD. Is cannabis use associated with an increased risk of onset and persistence of alcohol use disorders? A three-year prospective study among adults in the United States. Drug Alcohol Depend. 2016;161:363–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Agrawal A, Budney AJ, Lynskey MT. The co-occurring use and misuse of cannabis and tobacco: a review. Addiction. 2012;107:1221–33.

Article  PubMed  PubMed Central  Google Scholar 

Weinberger AH, Pacek LR, Wall MM, Gbedemah M, Lee J, Goodwin RD. Cigarette smoking quit ratios among adults in the USA with cannabis use and cannabis use disorders, 2002-16. Tob Control. 2020;29:74–80.

Article  PubMed  Google Scholar 

Millar SR, Mongan D, Smyth BP, Perry IJ, Galvin B. Relationships between age at first substance use and persistence of cannabis use and cannabis use disorder. BMC Public Health. 2021;21:997.

留言 (0)

沒有登入
gif