Hewitt R, Farne H, Ritchie A, Luke E, Johnston SL, Mallia P. The role of viral infections in exacerbations of chronic obstructive pulmonary disease and asthma. Ther Adv Respir Dis. 2016;10:158–74.
De Serres G, Lampron N, La Forge J, Rouleau I, Bourbeau J, Weiss K, Barret B, Boivin G. Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations. J Clin Virol. 2009;46:129–33.
Article PubMed PubMed Central Google Scholar
Bouquet J, Tabor DE, Silver JS, Nair V, Tovchigrechko A, Griffin MP, Esser MT, Sellman BR, Jin H. Microbial burden and viral exacerbations in a longitudinal multicenter COPD cohort. Respir Res. 2020;21:77.
Article CAS PubMed PubMed Central Google Scholar
Pawełczyk M, Kowalski ML. The role of human parainfluenza virus infections in the immunopathology of the respiratory tract. Curr Allergy Asthma Rep. 2017;17:16.
Article PubMed PubMed Central Google Scholar
Zhang L, Bukreyev A, Thompson CI, Watson B, Peeples ME, Collins PL, Pickles RJ. Infection of ciliated cells by human parainfluenza virus type 3 in an in vitro model of human airway epithelium. J Virol. 2005;79:1113–24.
Article CAS PubMed PubMed Central Google Scholar
Russell CD, Unger SA, Walton M, Schwarze J. The human immune response to respiratory syncytial virus infection. Clin Microbiol Rev. 2017;30:481–502.
Article CAS PubMed PubMed Central Google Scholar
Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for illumina sequence data. Bioinformatics. 2014;30:2114–20.
Article CAS PubMed PubMed Central Google Scholar
Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR. STAR: ultrafast universal RNA-seq aligner. Bioinformatics. 2013;29:15–21.
Article CAS PubMed Google Scholar
Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15:550.
Article PubMed PubMed Central Google Scholar
Voynow JA, Rubin BK. Mucins, mucus, and sputum. Chest. 2009;135:505–12.
Article CAS PubMed Google Scholar
Gohy S, Carlier FM, Fregimilicka C, Detry B, Lecocq M, Ladjemi MZ, Verleden S, Hoton D, Weynand B, Bouzin C, Pilette C. Altered generation of ciliated cells in chronic obstructive pulmonary disease. Sci Rep. 2019;9:17963.
Article PubMed PubMed Central Google Scholar
Roessler FK, Benedikter BJ, Schmeck B, Bar N. Novel computational analysis of large transcriptome datasets identifies sets of genes distinguishing chronic obstructive pulmonary disease from healthy lung samples. Sci Rep. 2021;11:10258.
Article CAS PubMed PubMed Central Google Scholar
Steiling K, van den Berge M, Hijazi K, Florido R, Campbell J, Liu G, Xiao J, Zhang X, Duclos G, Drizik E, Si H, Perdomo C, Dumont C, Coxson HO, Alekseyev YO, Sin D, Pare P, Hogg JC, McWilliams A, Hiemstra PS, Sterk PJ, Timens W, Chang JT, Sebastiani P, O’Connor GT, Bild AH, Postma DS, Lam S, Spira A, Lenburg ME. A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. Am J Respir Crit Care Med. 2013;187:933–42.
Article CAS PubMed PubMed Central Google Scholar
Mostafaei S, Kazemnejad A, Azimzadeh Jamalkandi S, Amirhashchi S, Donnelly SC, Armstrong ME, Doroudian M. Identification of novel genes in human airway epithelial cells associated with chronic obstructive Pulmonary Disease (COPD) using machine-based learning algorithms. Sci Rep. 2018;8:15775.
Article PubMed PubMed Central Google Scholar
Camargo L, do N, Righetti RF, de Almeida FM, Dos Santos TM, Fukuzaki S, Martins NAB, Barbeiro MC, Saraiva-Romanholo BM, Lopes FDTQDS, Leick EA, Prado CM. Tibério I De FLC. Modulating asthma-COPD overlap responses with IL-17 inhibition. Front Immunol. 2023;14:1271342.
Mebratu YA, Tesfaigzi Y. IL-17 plays a role in respiratory syncytial virus-induced lung inflammation and emphysema in elastase and LPS-injured mice. Am J Respir Cell Mol Biol. 2018;58:717–26.
Article CAS PubMed PubMed Central Google Scholar
Ma R, Su H, Jiao K, Liu J. Association between IL-17 and chronic obstructive pulmonary disease: a systematic review and meta-analysis. Int J Chron Obstruct Pulmon Dis. 2023;18:1681–90.
Article CAS PubMed PubMed Central Google Scholar
Yang J, Tian B, Sun H, Garofalo RP, Brasier AR. Epigenetic silencing of IRF1 dysregulates type III interferon responses to respiratory virus infection in epithelial to mesenchymal transition. Nat Microbiol. 2017;2:17086.
Article CAS PubMed PubMed Central Google Scholar
Lukashev D, Klebanov B, Kojima H, Grinberg A, Ohta A, Berenfeld L, Wenger RH, Ohta A, Sitkovsky M. Cutting edge: hypoxia-inducible factor 1alpha and its activation-inducible short isoform I.1 negatively regulate functions of CD4 + and CD8 + T lymphocytes. J Immunol. 2006;177:4962–5.
Article CAS PubMed Google Scholar
Jing Y, Gimenes JA, Mishra R, Pham D, Comstock AT, Yu D, Sajjan U. NOTCH3 contributes to rhinovirus-induced goblet cell hyperplasia in COPD airway epithelial cells. Thorax. 2019;74:18–32.
Garcia GL, Valenzuela A, Manzoni T, Vaughan AE, López CB. Distinct chronic post-viral lung diseases upon infection with influenza or parainfluenza viruses differentially impact superinfection outcome. Am J Pathol. 2020;190:543–53.
Article CAS PubMed PubMed Central Google Scholar
Zhang L, Collins PL, Lamb RA, Pickles RJ. Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus. Virology. 2011;421:67–77.
Article CAS PubMed Google Scholar
Schaap-Nutt A, Liesman R, Bartlett EJ, Scull MA, Collins PL, Pickles RJ, Schmidt AC. Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium. Virology. 2012;433:320–8.
Article CAS PubMed Google Scholar
Kumar RK, Foster PS, Rosenberg HF. Respiratory viral infection, epithelial cytokines, and innate lymphoid cells in asthma exacerbations. J Leukoc Biol. 2014;96:391–6.
Article PubMed PubMed Central Google Scholar
Schneider D, Ganesan S, Comstock AT, Meldrum CA, Mahidhara R, Goldsmith AM, Curtis JL, Martinez FJ, Hershenson MB, Sajjan U. Increased cytokine response of rhinovirus-infected airway epithelial cells in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010;182:332–40.
Article CAS PubMed PubMed Central Google Scholar
Veerati PC, Troy NM, Reid AT, Li NF, Nichol KS, Kaur P, Maltby S, Wark PAB, Knight DA, Bosco A, Grainge CL, Bartlett NW. Airway epithelial cell immunity is delayed during rhinovirus infection in asthma and COPD. Front Immunol. 2020;11:974.
留言 (0)