Adamowicz M, Milkiewicz P, Kempinska-Podhorodecka A (2021) 5-aminosalicylic acid inhibits the expression of oncomiRs and pro-inflammatory microRNAs: an in vitro study. J Physiol Pharmacol 72(4):529–535. https://doi.org/10.26402/jpp.2021.4.04

Article  CAS  Google Scholar 

Bindea G, Mlecnik B, Hackl H et al (2009) ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks. Bioinformatics 25:1091–1093. https://doi.org/10.1093/BIOINFORMATICS/BTP101

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bruderer R, Bernhardt OM, Gandhi T et al (2015) Extending the limits of quantitative proteome profiling with data-independent acquisition and application to acetaminophen-treated three-dimensional liver microtissues. Mol Cell Proteomics 14:1400–1410. https://doi.org/10.1074/MCP.M114.044305

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ciszek-Lenda M, Majka G, Suski M et al (2023) Biofilm-forming strains of P. aeruginosa and S. aureus isolated from cystic fibrosis patients differently affect inflammatory phenotype of macrophages. Inflamm Res 72:1275. https://doi.org/10.1007/S00011-023-01743-X

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deutsch EW, Bandeira N, Perez-Riverol Y et al (2023) The ProteomeXchange consortium at 10 years: 2023 update. Nucleic Acids Res 51:D1539. https://doi.org/10.1093/NAR/GKAC1040

Article  PubMed  Google Scholar 

Fang J, George MG, Gindi RM et al (2015) Use of low-dose aspirin as secondary prevention of atherosclerotic cardiovascular disease in US Adults (from the National Health Interview Survey, 2012). Am J Cardiol 115:895–900. https://doi.org/10.1016/J.AMJCARD.2015.01.014

Article  CAS  PubMed  PubMed Central  Google Scholar 

Farrugia G, Szurszewski JH (2014) Carbon monoxide, hydrogen sulfide, and nitric oxide as signaling molecules in the gastrointestinal tract. Gastroenterology 147:303–313. https://doi.org/10.1053/J.GASTRO.2014.04.041

Article  CAS  PubMed  Google Scholar 

Fornai M, Antonioli L, Colucci R et al (2011) Pathophysiology of gastric ulcer development and healing: molecular mechanisms and novel therapeutic options. Peptic Ulcer Dis. https://doi.org/10.5772/17640

Article  Google Scholar 

Gilbert AK, Pluth MD (2022) Subcellular delivery of hydrogen sulfide using small molecule donors impacts organelle stress. J Am Chem Soc 144:17651–17660. https://doi.org/10.1021/JACS.2C07225

Article  CAS  PubMed  PubMed Central  Google Scholar 

Glowacka U, Magierowska K, Wójcik D et al (2022) Microbiome profile and molecular pathways alterations in gastrointestinal tract by hydrogen sulfide-releasing nonsteroidal anti-inflammatory drug (ATB-352): insight into possible safer polypharmacy. Antioxid Redox Signal 36:189–210. https://doi.org/10.1089/ARS.2020.8240

Article  CAS  PubMed  Google Scholar 

Głowacka U, Magierowski M, Śliwowski Z et al (2023) Hydrogen sulfide-releasing indomethacin-derivative (ATB-344) prevents the development of oxidative gastric mucosal injuries. Antioxidants. 12:1545

Article  PubMed  PubMed Central  Google Scholar 

Halter F, Schmassmann A, Tarnawski A (1995) Healing of experimental gastric ulcers - Interference by gastric acid. Dig Dis Sci 40:2481–2486. https://doi.org/10.1007/BF02063260/METRICS

Article  CAS  PubMed  Google Scholar 

Kolgazi M, Ozdemir-Kumral ZN, Cantali-Ozturk C et al (2017) Anti-inflammatory effects of nesfatin-1 on acetic acid-induced gastric ulcer in rats: involvement of cyclo-oxygenase pathway. J Physiol Pharmacol 68:756–777

Google Scholar 

Kuna L, Jakab J, Smolic R et al (2019) Peptic ulcer disease: a brief review of conventional therapy and herbal treatment options. J Clin Med 8:179. https://doi.org/10.3390/JCM8020179

Article  CAS  PubMed  PubMed Central  Google Scholar 

Magierowska K, Bakalarz D, Wójcik D et al (2019) Time-dependent course of gastric ulcer healing and molecular markers profile modulated by increased gastric mucosal content of carbon monoxide released from its pharmacological donor. Biochem Pharmacol 163:71–83. https://doi.org/10.1016/j.bcp.2019.02.011

Article  CAS  PubMed  Google Scholar 

Magierowska K, Wójcik-Grzybek D, Korbut E et al (2023) The mitochondria-targeted sulfide delivery molecule attenuates drugs-induced gastropathy. Involvement of heme oxygenase pathway. Redox Biol 66:102847. https://doi.org/10.1016/J.REDOX.2023.102847

Article  CAS  PubMed  PubMed Central  Google Scholar 

Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Sliwowski Z, Pajdo R, Ginter G, Kwiecien S, Brzozowski T (2017) Exogenous and endogenous hydrogen sulfide protects gastric mucosa against the formation and time-dependent development of ischemia/reperfusion-induced acute lesions progressing into deeper ulcerations. Molecules 22(2):295. https://doi.org/10.3390/molecules22020295

Article  CAS  PubMed  PubMed Central  Google Scholar 

Magierowski M, Magierowska K, Hubalewska-Mazgaj M et al (2018) Cross-talk between hydrogen sulfide and carbon monoxide in the mechanism of experimental gastric ulcers healing, regulation of gastric blood flow and accompanying inflammation. Biochem Pharmacol 149:131–142. https://doi.org/10.1016/J.BCP.2017.11.020

Article  CAS  PubMed  Google Scholar 

Malik TF, Gnanapandithan K, Singh K (2023) Peptic Ulcer Disease. Sex/Gender-Specific Medicine in the Gastrointestinal Diseases 131–151. Doi: https://doi.org/10.1007/978-981-19-0120-1_9

Opoka W, Adamek D, Plonka M et al (2010) Importance of luminal and mucosal zinc in the mechanism of experimental gastric ulcer healing. J Physiol Pharmacol 61:581–591

CAS  PubMed  Google Scholar 

Pavlovskiy Y, Yashchenko A, Zayachkivska O (2020) H2S donors reverse age-related gastric malfunction impaired due to fructose-induced injury via CBS, CSE, and TST expression. Front Pharmacol 11:558245

Article  Google Scholar 

Pihan G, Majzoubi D, Haudenschild C et al (1986) Early microcirculatory stasis in acute gastric mucosal injury in the rat and prevention by 16,16-dimethyl prostaglandin E2 or sodium thiosulfate. Gastroenterology 91:1415–1426. https://doi.org/10.1016/0016-5085(86)90195-2

Article  CAS  PubMed  Google Scholar 

Shannon P, Markiel A, Ozier O et al (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 13:2498. https://doi.org/10.1101/GR.1239303

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sostres C, Lanas A (2011) Gastrointestinal effects of aspirin. Nat Rev Gastroenterol Hepatol 8(7):385–394. https://doi.org/10.1038/nrgastro.2011.97

Article  CAS  PubMed  Google Scholar 

Storey JD (2002) A direct approach to false discovery rates. J R Stat Soc Series B Stat Methodol 64:479–498. https://doi.org/10.1111/1467-9868.00346

Article  Google Scholar 

Sundararaman N, Go J, Robinson AE et al (2020) PINE: an automation tool to extract and visualize protein-centric functional networks. J Am Soc Mass Spectrom 31:1410–1421. https://doi.org/10.1021/JASMS.0C00032

Article  CAS  PubMed  PubMed Central  Google Scholar 

Szabo C, Ransy C, Módis K et al (2014) Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms. Br J Pharmacol 171:2099–2122. https://doi.org/10.1111/bph.12369

Article  CAS  PubMed  PubMed Central  Google Scholar 

Takagi K, Okabe S, Saziki R (1969) A new method for the production of chronic gastric ulcer in rats and the effect of several drugs on its healing. Jpn J Pharmacol 19:418–426. https://doi.org/10.1254/jjp.19.418

Article  CAS  PubMed  Google Scholar 

Wallace JL, Wang R (2015) Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter. Nat Rev Drug Discov 14(5):329–345. https://doi.org/10.1038/nrd4433

Article  CAS  PubMed  Google Scholar 

Wallace JL, Dicay M, McKnight W, Martin GR (2007) Hydrogen sulfide enhances ulcer healing in rats. FASEB J 21:4070–4076. https://doi.org/10.1096/FJ.07-8669COM

Article  CAS  PubMed  Google Scholar 

Wallace JL, Blackler RW, Chan MV et al (2015) Anti-Inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics. Antioxid Redox Signal 22:398–410. https://doi.org/10.1089/ARS.2014.5901

Article  CAS  PubMed  Google Scholar 

Wallace JL, Vaughan D, Dicay M et al (2018) Hydrogen sulfide-releasing therapeutics: translation to the clinic. Antioxid Redox Signal 28:1533–1540. https://doi.org/10.1089/ARS.2017.7068

Article  CAS  PubMed  Google Scholar 

Wiśniewski JR, Zougman A, Nagaraj N, Mann M (2009) Universal sample preparation method for proteome analysis. Nat Methods 6(5):359–362

Article  PubMed  Google Scholar 

Wisniewski JR, Gaugaz FZ (2015) Fast and sensitive total protein and peptide assays for proteomic analysis. Anal Chem 87:4110–4116. https://doi.org/10.1021/AC504689Z/ASSET/IMAGES/LARGE/AC-2014-04689Z_0006.JPEG

Article  CAS  PubMed  Google Scholar 

Yao M, Li F, Xu L et al (2022) 24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation. Bioengineered 13:155–163. https://doi.org/10.1080/21655979.2021.2011634

Article