Background: Resistance to antibiotics has increased dramatically over the past few years and has now reached a level that places future patients in real danger. Several factors contribute to this problem, some of them are health workers related and others are community related. This study aimed to assess the awareness of doctors in Elobeid hospital, North Kordofan state, Sudan about the problem, its causes, and its possible preventive measures.

Methods: This descriptive, questionnaire-based study was conducted in Elobeid teaching hospital between 2020, February 27 and March 13. The study involved 50 doctors in the internal medicine department.

Results: Out of the 50 doctors involved, 49 (98%) agreed that antibiotics resistance is a big progressive health threat in Sudan; 86% of the participants think that selfmedication is the leading cause of antibiotic resistance; and 98% believe that providing good quality culture and sensitivity service in hospitals and health centers is the most effective preventive measure. Regarding education about antibiotics as a part of academic activities in the unit during the last year, 36% of the participants received zero sessions, 68% received 1–5 sessions, and 12% received more than 5 sessions. The assessment of doctor’s adherence to the Sudan Standard Treatment Guideline revealed that 28/50 participants (56%) did not see it or hear about it, 17/50 participants (34%) know it but don’t comply, and only 5/50 participants (10%) know it and comply with it.

Conclusion: Participants show a good awareness about the significance of antibiotics resistance as a health threat, a good awareness about the main causes and the possible preventive measures, a low to moderate frequency of education on antibiotics, and a very poor adherence to the Sudan Standard Treatment Guidelines.

[1] Franco, B. E., Altagracia Martínez, M., Sánchez Rodríguez, M. A., & Wertheimer, A. I. (2009). The determinants of the antibiotic resistance process. Infection and Drug Resistance, 2, 1–11.

[2] Bennett, J. W., & Chung, K.-T. (2001). Alexander Fleming and the discovery of penicillin. Advances in Applied Microbiology, 49, 163-184. https://doi.org/10.1016/S0065-2164(01)49013-7

[3] Lobanovska, M., & Pilla, G. (2017). Penicillin’s discovery and antibiotic resistance: Lessons for the future? The Yale Journal of Biology and Medicine, 90(1), 135–145.

[4] O’Neill, J. (May 2016). Tackling drug-resistant infections globally. Final Report & Recommendations. The Review on Antimicrobial Resistance. Wellcome Trust.

[5] Carlet, J., Jarlier, V., Harbarth, S., Voss, A., Gossens, H., Pittet, D., & the Participants of the 3rd World Healthcare-Associated Infections Forum. (2012). Ready for a world without antibiotics? The Pensières Antibiotic Resistance Call to Action. Antimicrobial Resistance and Infection Control, 1, 11. https://doi.org/10.1186/2047-2994-1-11

[6] Servitje, L. (2019). Gaming the apocalypse in the time of antibiotic resistance. Osiris, 34(1), 316–337. https://doi.org/10.1086/704048

[7] Oleim, S. H. K., Noor, S. O., Bushara, S., Ahmed, M. H., & Elmadhoun, W. (2019). The irrational use of antibiotics among doctors, pharmacists and the public in river Nile state, Sudan. Sudan Journal of Medical Sciences. Advance online publication. https://doi.org/10.18502/sjms.v14i4.5909

[8] Kheder, S. I. (2012). Physicians’ knowledge and perception of antimicrobial resistance: A survey in Khartoum State Hospital settings. British Journal of Pharmaceutical Research, 3(3), 347–362. https://doi.org/10.9734/BJPR/2013/2117

[9] Elfaki, A. (2009). Assessment of antibiotics prescription in hospitalized patients at Elobeid Hospital, Sudan. Sudan Journal of Medical Sciences, 4(3). Advance online publication. https://doi.org/10.4314/sjms.v4i3.48321

[10] Labi, A.-K., Obeng-Nkrumah, N., Bjerrum, S., Aryee, N. A. A., Ofori-Adjei, Y. A., Yawson, A. E., & Newman, M. J. (2018). Physicians’ knowledge, attitudes, and perceptions concerning antibiotic resistance: A survey in a Ghanaian tertiary care hospital. BMC Health Services Research, 18(1), 126. https://doi.org/10.1186/s12913-018-2899-y

[11] Lindonne, G., Stephanie, F.-L., Owen, G., & Martin, F. (2018). Health care practitioners level of awareness on antimicrobial resistance in Grenada. Journal of Family Medicine and Disease Prevention, 4(4). Advance online publication. https://doi.org/10.23937/2469-5793/1510093

[12] Alzoubi, K., Ayoub, N., Al-Sakaji, S., Al-Azzam, S., Mhaidat, N., & Masadeh, M. (2009). Awareness of bacterial resistance among physicians, pharmacists and nurses. International Journal of Occupational Medicine and Environmental Health, 22(4), 363–372. Advance online publication. https://doi.org/10.2478/v10001-009-0034-3

[13] Balliram, R., Sibanda, W., & Essack, S. Y. (2021). The knowledge, attitudes and practices of doctors, pharmacists and nurses on antimicrobials, antimicrobial resistance and antimicrobial stewardship in South Africa. Southern African Journal of Infectious Diseases, 36(1), 262. Advance online publication. https://doi.org/10.4102/sajid.v36i1.262

[14] Chokshi, A., Sifri, Z., Cennimo, D., & Horng, H. (2019). Global contributors to antibiotic resistance. Journal of Global Infectious Diseases, 11(1), 36–42. https://doi.org/10.4103/jgid.jgid_110_18