Rosenfield RL, Ehrmann DA. The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited. Endocr Rev. 2016;37(5):467–520.
Article CAS PubMed PubMed Central Google Scholar
Ganie MA, et al. Epidemiology, pathogenesis, genetics & management of polycystic ovary syndrome in India. Indian J Med Res. 2019;150(4):333–44.
Article CAS PubMed PubMed Central Google Scholar
Skiba MA, et al. Understanding variation in prevalence estimates of polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod Update. 2018;24(6):694–709.
Torres PJ, et al. Gut microbial diversity in women with polycystic ovary syndrome correlates with hyperandrogenism. J Clin Endocrinol Metab. 2018;103(4):1502–11.
Article PubMed PubMed Central Google Scholar
Qi X, et al. Gut microbiota-bile acid-interleukin-22 axis orchestrates polycystic ovary syndrome. Nat Med. 2019;25(8):1225–33.
Article CAS PubMed PubMed Central Google Scholar
Chu W, et al. Metagenomic analysis identified microbiome alterations and pathological association between intestinal microbiota and polycystic ovary syndrome. Fertil Steril. 2020;113(6):1286–98. e4.
Article CAS PubMed Google Scholar
Zhao H, et al. Modified Banxia Xiexin decoction ameliorates polycystic ovarian syndrome with insulin resistance by regulating intestinal microbiota. Front Cell Infect Microbiol. 2022;12:854796.
Article CAS PubMed PubMed Central Google Scholar
Yang YL et al. Intestinal flora is a key factor in insulin resistance and contributes to the development of polycystic ovary syndrome. Endocrinology. 2021;162(10).
Ascani A et al. The role of B cells in immune cell activation in polycystic ovary syndrome. Elife. 2023;12.
Kicinska AM et al. Immunological and metabolic causes of infertility in polycystic ovary syndrome. Biomedicines. 2023;11(6).
Zhang F, et al. Diversity of the gut microbiota in dihydrotestosterone-induced PCOS rats and the pharmacologic effects of Diane-35, probiotics, and berberine. Front Microbiol. 2019;10:175.
Article CAS PubMed PubMed Central Google Scholar
Camara NO, et al. Kidney disease and obesity: epidemiology, mechanisms and treatment. Nat Rev Nephrol. 2017;13(3):181–90.
Azziz R, et al. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016;2:16057.
Dumesic DA, Abbott DH, Chazenbalk GD. An evolutionary model for the ancient origins of polycystic ovary syndrome. J Clin Med. 2023;12(19).
Vink JM, et al. Heritability of polycystic ovary syndrome in a Dutch twin-family study. J Clin Endocrinol Metab. 2006;91(6):2100–4.
Article CAS PubMed Google Scholar
Kahsar-Miller MD, et al. Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS. Fertil Steril. 2001;75(1):53–8.
Article CAS PubMed Google Scholar
Welt CK, et al. Variants in DENND1A are associated with polycystic ovary syndrome in women of European ancestry. J Clin Endocrinol Metab. 2012;97(7):E1342–7.
Article CAS PubMed PubMed Central Google Scholar
Saxena R, et al. Han Chinese polycystic ovary syndrome risk variants in women of European ancestry: relationship to FSH levels and glucose tolerance. Hum Reprod. 2015;30(6):1454–9.
Article CAS PubMed PubMed Central Google Scholar
Jones MR, et al. Systems genetics reveals the functional context of PCOS loci and identifies genetic and molecular mechanisms of disease heterogeneity. PLoS Genet. 2015;11(8):e1005455.
Article PubMed PubMed Central Google Scholar
Shi Y, et al. Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet. 2012;44(9):1020–5.
Article CAS PubMed Google Scholar
Hayes MG, et al. Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. Nat Commun. 2015;6:7502.
Article CAS PubMed Google Scholar
Stavridis K et al. Bisphenol-A and female fertility: an update of existing epidemiological studies. J Clin Med. 2022;11(23).
Jurewicz J, et al. Serum bisphenol a analogues in women diagnosed with the polycystic ovary syndrome - is there an association? Environ Pollut. 2021;272:115962.
Article CAS PubMed Google Scholar
Gu J, et al. Urinary concentration of personal care products and polycystic ovary syndrome: a case-control study. Environ Res. 2019;168:48–53.
Article CAS PubMed Google Scholar
Prabhu NB, et al. Distinct metabolic signatures in blood plasma of bisphenol A-exposed women with polycystic ovarian syndrome. Environ Sci Pollut Res Int. 2023;30(23):64025–35.
Article CAS PubMed PubMed Central Google Scholar
Bellver J, et al. Polycystic ovary syndrome throughout a woman’s life. J Assist Reprod Genet. 2018;35(1):25–39.
Chen ZJ, et al. Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat Genet. 2011;43(1):55–9.
Lund LH, et al. Association of spironolactone use with all-cause mortality in heart failure: a propensity scored cohort study. Circ Heart Fail. 2013;6(2):174–83.
Article CAS PubMed Google Scholar
Lima PDA, et al. Polycystic ovary syndrome: possible involvement of androgen-induced, chemerin-mediated ovarian recruitment of monocytes/macrophages. Biol Reprod. 2018;99(4):838–52.
Article PubMed PubMed Central Google Scholar
Cassar S, et al. Insulin resistance in polycystic ovary syndrome: a systematic review and meta-analysis of euglycaemic-hyperinsulinaemic clamp studies. Hum Reprod. 2016;31(11):2619–31.
Article CAS PubMed Google Scholar
Chen Z et al. Impact of preservation method and 16S rRNA hypervariable region on gut microbiota profiling. mSystems. 2019;4(1).
Zmora N, et al. Personalized gut mucosal colonization resistance to empiric probiotics is associated with unique host and microbiome features. Cell. 2018;174(6):1388–405. e21.
Article CAS PubMed Google Scholar
Zmora N, Suez J, Elinav E. You are what you eat: diet, health and the gut microbiota. Nat Rev Gastroenterol Hepatol. 2019;16(1):35–56.
Article CAS PubMed Google Scholar
Fan Y, Pedersen O. Gut microbiota in human metabolic health and disease. Nat Rev Microbiol. 2021;19(1):55–71.
Article CAS PubMed Google Scholar
Gentile CL, Weir TL. The gut microbiota at the intersection of diet and human health. Science. 2018;362(6416):776–80.
Article CAS PubMed Google Scholar
Gilbert JA, et al. Current understanding of the human microbiome. Nat Med. 2018;24(4):392–400.
Article CAS PubMed PubMed Central Google Scholar
Falony G, et al. The human microbiome in health and disease: hype or hope. Acta Clin Belg. 2019;74(2):53–64.
Tremellen K, Pearce K. Dysbiosis of gut microbiota (DOGMA)--a novel theory for the development of polycystic ovarian syndrome. Med Hypotheses. 2012;79(1):104–12.
Lindheim L, et al. Alterations in gut microbiome composition and barrier function are associated with reproductive and metabolic defects in women with polycystic ovary syndrome (PCOS): a pilot study. PLoS ONE. 2017;12(1):e0168390.
Article PubMed PubMed Central Google Scholar
Furusawa Y, et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature. 2013;504(7480):446–50.
Article CAS PubMed Google Scholar
Qin L, et al. Differential expression profile of immunological cytokines in local ovary in patients with polycystic ovarian syndrome: analysis by flow cytometry. Eur J Obstet Gynecol Reprod Biol. 2016;197:136–41.
Article CAS PubMed Google Scholar
Atarashi K, et al. Treg induction by a rationally selected mixture of clostridia strains from the human microbiota. Nature. 2013;500(7461):232–6.
Article CAS PubMed Google Scholar
Yang Y, et al. The abnormal level of HSP70 is related to Treg/Th17 imbalance in PCOS patients. J Ovarian Res. 2021;14(1):155.
留言 (0)