Inhibition of TLR4/NF-κB pathway and endoplasmic reticulum stress by overexpressed S100A4 ameliorates retinal ischemia-reperfusion injury of mice

Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY (2014) Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 121:2081–2090

Article  PubMed  Google Scholar 

Maggio F (2015) Glaucomas. Top Companion Anim Med 30:86–96

Article  PubMed  Google Scholar 

Osborne NN, Casson RJ, Wood JP, Chidlow G, Graham M, Melena J (2004) Retinal ischemia: mechanisms of damage and potential therapeutic strategies. Prog Retin Eye Res 23:91–147

Article  CAS  PubMed  Google Scholar 

Shosha E, Xu Z, Yokota H et al (2016) Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury. Cell Death Dis 7:e2483

Article  CAS  PubMed  PubMed Central  Google Scholar 

Palmhof M, Frank V, Rappard P et al (2019) From ganglion cell to photoreceptor layer: timeline of deterioration in a rat ischemia/reperfusion model. Front Cell Neurosci 13:174

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hayreh SS, Zimmerman MB, Kimura A, Sanon A (2004) Central retinal artery occlusion. Retinal survival time. Exp Eye Res 78:723–736

Article  CAS  PubMed  Google Scholar 

Tarabykina S, Kriajevska M, Scott DJ et al (2000) Heterocomplex formation between metastasis-related protein S100A4 (Mts1) and S100A1 as revealed by the yeast two-hybrid system. FEBS Lett 475:187–191

Article  CAS  PubMed  Google Scholar 

Donato R (2003) Intracellular and extracellular roles of S100 proteins. Microsc Res Tech 60:540–551

Article  CAS  PubMed  Google Scholar 

Schneider M, Hansen JL, Sheikh SP (2008) S100A4: a common mediator of epithelial-mesenchymal transition, fibrosis and regeneration in diseases? J Mol Med (Berl) 86:507–522

Article  CAS  PubMed  Google Scholar 

Ambartsumian N, Klingelhofer J, Grigorian M et al (2001) The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor. Oncogene 20:4685–4695

Article  CAS  PubMed  Google Scholar 

Gross SR, Sin CG, Barraclough R, Rudland PS (2014) Joining S100 proteins and migration: for better or for worse, in sickness and in health. Cell Mol Life Sci 71:1551–1579

Article  CAS  PubMed  Google Scholar 

Donato R, Cannon BR, Sorci G et al (2013) Functions of S100 proteins. Curr Mol Med 13:24–57

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dmytriyeva O, Pankratova S, Owczarek S et al (2012) The metastasis-promoting S100A4 protein confers neuroprotection in brain injury. Nat Commun 3:1197

Article  PubMed  Google Scholar 

Pedersen MV, Kohler LB, Grigorian M et al (2004) The Mts1/S100A4 protein is a neuroprotectant. J Neurosci Res 77:777–786

Article  CAS  PubMed  Google Scholar 

Abu El-Asrar AM, Nawaz MI, De Hertogh G et al (2014) S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis. Mol Vis 20:1209–1224

CAS  PubMed  PubMed Central  Google Scholar 

Maddala R, Gao J, Mathias RT et al (2021) Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract. Sci Rep 11:2203

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheng G, Tian K, Zhang L, Yang N, Xing Y, He T (2016) S100A4 gene silencing in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via down-regulation of CREB expression. Graefes Arch Clin Exp Ophthalmol 254:97–108

Article  CAS  PubMed  Google Scholar 

Cheng G, He T, Xing Y (2016) Silencing of S100A4, a metastasis-associated protein, inhibits retinal neovascularization via the downregulation of BDNF in oxygen-induced ischaemic retinopathy. Eye (Lond) 30:877–887

Article  CAS  PubMed  Google Scholar 

Yang J, Yang N, Luo J et al (2020) Overexpression of S100A4 protects retinal ganglion cells against retinal ischemia-reperfusion injury in mice. Exp Eye Res 201:108281

Article  CAS  PubMed  Google Scholar 

Sakamoto K, Yonoki Y, Kubota Y et al (2006) Inducible nitric oxide synthase inhibitors abolished histological protection by late ischemic preconditioning in rat retina. Exp Eye Res 82:512–518

Article  CAS  PubMed  Google Scholar 

Stankowska DL, Minton AZ, Rutledge MA et al (2015) Neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma. Invest Ophthalmol Vis Sci 56:893–907

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chiu K, Chang RC, So KF (2007) Intravitreous injection for establishing ocular diseases model. J Vis Exp:313

Liu W, Xia F, Ha Y et al (2019) Neuroprotective effects of HSF1 in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci 60:965–977

Article  CAS  PubMed  PubMed Central  Google Scholar 

Do YJ, Sul JW, Jang KH et al (2017) A novel RIPK1 inhibitor that prevents retinal degeneration in a rat glaucoma model. Exp Cell Res 359:30–38

Article  CAS  PubMed  Google Scholar 

Ha Y, Liu H, Xu Z et al (2015) Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma. Cell Death Dis 6:e1900

Article  CAS  PubMed  PubMed Central  Google Scholar 

Minhas G, Sharma J, Khan N (2016) Cellular stress response and immune signaling in retinal ischemia-reperfusion injury. Front Immunol 7:444

Article  PubMed  PubMed Central  Google Scholar 

Jeon CJ, Strettoi E, Masland RH (1998) The major cell populations of the mouse retina. J Neurosci 18:8936–8946

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang C, Yu WQ, Hoshino A et al (2019) Development of ON and OFF cholinergic amacrine cells in the human fetal retina. J Comp Neurol 527:174–186

Article  CAS  PubMed  Google Scholar 

Chen GY, Nunez G (2010) Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol 10:826–837

Article  CAS  PubMed  PubMed Central  Google Scholar 

Belvin MP, Anderson KV (1996) A conserved signaling pathway: the Drosophila toll-dorsal pathway. Annu Rev Cell Dev Biol 12:393–416

Article  CAS  PubMed  Google Scholar 

Schlueter C, Weber H, Meyer B et al (2005) Angiogenetic signaling through hypoxia: HMGB1: an angiogenetic switch molecule. Am J Pathol 166:1259–1263

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hoshino K, Kaisho T, Iwabe T, Takeuchi O, Akira S (2002) Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation. Int Immunol 14:1225–1231

Article  CAS  PubMed  Google Scholar 

Schneider A, Martin-Villalba A, Weih F, Vogel J, Wirth T, Schwaninger M (1999) NF-kappaB is activated and promotes cell death in focal cerebral ischemia. Nat Med 5:554–559

Article  CAS  PubMed  Google Scholar 

Qi Y, Zhao M, Bai Y et al (2014) Retinal ischemia/reperfusion injury is mediated by Toll-like receptor 4 activation of NLRP3 inflammasomes. Invest Ophthalmol Vis Sci 55:5466–5475

Article  CAS  PubMed  Google Scholar 

Cerezo LA, Remakova M, Tomcik M et al (2014) The metastasis-associated protein S100A4 promotes the inflammatory response of mononuclear cells via the TLR4 signalling pathway in rheumatoid arthritis. Rheumatology (Oxford) 53:1520–1526

Article  CAS  PubMed  Google Scholar 

Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, Yamate J (2016) The kinetics of damage-associated molecular patterns (DAMPs) and toll-like receptors during thioacetamide-induced acute liver injury in rats. Exp Toxicol Pathol 68:471–477

Article  CAS  PubMed  Google Scholar 

Ha Y, Liu W, Liu H et al (2018) AAV2-mediated GRP78 transfer alleviates retinal neuronal injury by downregulating ER stress and Tau oligomer formation. Invest Ophthalmol Vis Sci 59:4670–4682

Article  CAS  PubMed  PubMed Central 

留言 (0)

沒有登入
gif