post-translational modification

SUMO interactive motif

protein–protein interaction

kinase signaling

SUMO mechanism

SUMO isoforms

lysine-site regulation

nutrient signaling

amino acid stimulation

Dulbecco's modified Eagle’s medium

G protein β-subunit–like protein

glutathione-S-transferase

human embryonic kidney 293 cell line

lithium dodecyl sulfate

mouse embryonic fibroblast

mechanistic target of rapamycin

National Institutes of Health

National Institute of Neurological Disorders and Stroke

nickel–nitrilotriacetic acid

regulatory protein associated with mTOR

rapamycin-insensitive companion of mTOR

small ubiquitin–like modifier

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